The only way to improve cancer detection, prevention, and treatment is through research. People participating in research contribute to medical knowledge and have opportunity to receive cutting-edge care.
Search Results: Prevention, Detection & Risk + Pancreatic Cancer (6 results)
People with a BRCA1 or BRCA2 mutation
This study will look at a new vaccine known as INO-5401 used alone or combined with a second vaccine called INO-9012. The study will test if the vaccine is safe (without large side effects) and test a new way of giving vaccines. It will also test whether the vaccine activates the immune system. A goal of this research is to reduce cancer risk in people with a BRCA1 or BRCA2 mutation. Additional studies will be needed to learn if this vaccine approach lowers cancer risk in mutation carriers.
The purpose of this study is to try to find markers of early pancreatic cancer for screening for individuals at higher-than-average risk, expedite the diagnosis in individuals with symptoms, and substantially improve an individual's chance of surviving the disease.
Preliminary Evaluation of Screening for Pancreatic Cancer in Patients with an Inherited Genetic Risk Due to a BRCA1, BRCA2, PALB2 or ATM Mutation
Improved screening for pancreatic cancer in high-risk groups, such as people with an inherited BRCA1, BRCA2, ATM, or PALB2 mutation, may help find cancer early and improve survival rates. People enrolled in this study will undergo screening using endoscopic ultrasound or MRI of the abdomen.
The Ohio State University and FORCE want to understand if a family communication guide for people with BRCA mutations is helpful and if it’s also useful to have a video that you can text or email to family members that explains your BRCA mutation. We are currently looking for people between the ages of 18-80 who have mutation in BRCA1 or BRCA2, have an active email address, and an internet capable device like a computer, tablet, or smartphone. Participants will be asked to complete a total of 3 surveys. Participants will be randomly assigned to either receive just the communication guide or the guide plus the sharable. Each survey will take 10-15 minutes (the study could take up to 1.5 hours to complete depending on how much time you spend reviewing the study materials).
You can get more information or ask to participate in the study by sending an email to: email@example.com.
The purpose of this study is to screen and detect pancreatic cancer and precancer in people with either a strong family history of pancreatic cancer, or an inherited mutation associated with pancreatic cancer risk.
Magnetic Resonance Imaging (MRI) will be used to screen for early stage pancreatic cancer. Participants will also be asked to donate a blood sample at specific intervals for the creation of a blood bank necessary for the development of a blood-based screening test for pancreatic cancer.
Additional Results on Clinicaltrials.gov Prevention, Detection & Risk + Pancreatic Cancer
|Clinical Trial||Official Title|
|NCT03250078||A Pancreatic Cancer Screening Study in Hereditary High Risk Individuals|
|NCT02478892||Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk|
|NCT03937453||A Pancreatic Cancer Screening Study in Individuals With New-Onset Diabetes Mellitus|
|NCT04662879||Early Detection Initiative for Pancreatic Cancer|
|NCT04844970||Anamorelin Study for Advanced Pancreatic Cancer|
|NCT03568630||Blood Markers of Early Pancreas Cancer|
|NCT02206360||Pancreatic Cancer Early Detection Program|
|NCT04825834||DNA Evaluation of Fragments for Early Interception - Lung Cancer Training Study (DELFI-L101 Study)|
Research Search Tool Sponsored By:
This resource was made possible through an independent grant from Merck & Co., Inc.