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Our Featured Research Page lists cancer prevention, treatment and quality of life studies enrolling people with or at high risk for hereditary cancers. You can do a quick search to filter our featured studies by cancer type, study type or key word, or a more in-depth search through clinicaltrials.gov.

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Search Results: Prevention, Detection & Risk + Colorectal Cancer (7 results)

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Cancer Prevention Vaccine (Nous-209) for People with Lynch Syndrome

Prevention
Prevention study for people with Lynch syndrome

Cancer Prevention Vaccine (Nous-209) for People with Lynch Syndrome

This study is testing a vaccine, known as the Nous-209 vaccine, which is intended to decrease the chances that people with Lynch syndrome will develop polyps that can turn into cancer.

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Testing the Safety And Action of the Investigational Drug REC-4881 in People With Familial Adenomatous Polyposis (FAP)

Prevention
Prevention study for people with an APC mutation and FAP who have had colectomy surgery

Testing the Safety And Action of the Investigational Drug REC-4881 in People With Familial Adenomatous Polyposis (FAP) (TUPELO Study)

This study is looking at how safe and effective the research drug REC-4881 is for treating polyps in people with Familial Adenomatous Polyposis (FAP). Participants will receive the oral drug REC-4881. A participant's dose will depend on when they join the study. 

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Early Detection of Colorectal Cancer for People with Lynch Syndrome

Prevention
People with Lynch Syndrome at risk for colon cancer

Collecting Blood and Stool Samples to Detect Colorectal Cancer or Precancerous Polyps in Lynch Syndrome Patients, CORAL Study

This study will colect blood and stool samples to detect colorectal cancer or precancerous polyps in people with Lynch syndrome.

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My Best GI Eating Study

Prevention
Diet and weight loss study for people who are overweight and at increased risk of colorectal cancer

My Best GI Eating Study

This study will test three different diets in people who are overweight and who have an increased risk of colorectal cancer. The study will look at whether these diets improve eating and possibly lead to weight loss. 

 

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Studying the Use of Naproxen and Aspirin for Cancer Prevention in People with Lynch Syndrome

Prevention
Prevention study for people with Lynch syndrome

A Study Comparing Two Anti-inflammatory Medications Naproxen or Aspirin for Cancer Prevention in Lynch Syndrome

The trial is enrolling people with Lynch syndrome. On average, the length of this study will last one year from the start of enrollment to completion. The study will measure  the effect of naproxen or aspirin on the immune cells in the gastrointestinal tract of people with Lynch syndrome. The trial will also evaluate any symptoms from the medications and any other changes of the colon and rectum.

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Helping People With a Genetic Mutation in BRCA1, BRCA2 or Lynch Syndrome Talk to Their Family Members About Their Risk for Cancer and Find the Best Way to Get Family Members Tested

Prevention
People with a genetic mutation in BRCA1, BRCA2 or Lynch syndrome who have relatives who have not been tested

IGNITE-TX - Identifying Individuals for Genetic Testing for Familial Cancer

The IGNITE-TX study is all about helping people with a genetic mutation in BRCA1, BRCA2 or Lynch syndrome talk to their family members about their risk for cancer and find the best way to get family members tested.

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Atorvastatin ± Aspirin for Colorectal Cancer Prevention for People with Lynch Syndrome

Prevention

Atorvastatin ± Aspirin for Colorectal Cancer Prevention for People with Lynch Syndrome

This study will look at how well atorvastatin (a cholesterol lowering agent) works with or without aspirin in preventing colorectal cancer in people with Lynch syndrome. Atorvastatin may lower the risk of developing cancers in the colon and rectum. Aspirin may reduce the risk of colon polyps and colon cancers. Giving atorvastatin and aspirin may work better at reducing the risk of colorectal cancer (CRC) in high-risk individuals with Lynch syndrome.

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Additional Results on Clinicaltrials.gov Prevention, Detection & Risk + Colorectal Cancer
36 results
Clinical Trial Official Title
NCT05929820 Impact of Protect Your Colon™ on CRC Screening
NCT05980182 Engaging Black Men in Colorectal Cancer Screening
NCT04336397 Stool DNA to Improve Colorectal Cancer Screening Among Alaska Native People
NCT04427527 Accelerating Colorectal Cancer Screening Through Implementation Science in Appalachia
NCT05785780 Aim 3, Optimizing CRC Screening in Patients With Diabetes in Safety-net Primary Care Settings
NCT04890054 Screening More Patients for Colorectal Cancer Through Adapting and Refining Targeted Evidence-Based Interventions in Rural Settings, SMARTER CRC
NCT04192071 Virtual Human Delivered Nutrition Module for Colorectal Cancer Prevention
NCT04748380 Shared Decision-making and Colorectal Cancer Screening
NCT04313114 The PRIME-CRC Trial to Promote CRC Screening in Rural Communities
NCT03407417 A Patient-centered Intervention Using Technology to Reduce Colorectal Cancer Disparities in Primary Care
NCT05765214 Impact of Colorectal Cancer and Nutrition Education Program Among Minority Patients With Type 2 Diabetes
NCT05631873 Colonoscopy Screening: Setting Epic Follow-up Times
NCT03640208 Educate, Assess Risk and Overcoming Barriers to Colorectal Screening Among African Americans
NCT05419531 The Purpose of This Study is to Determine the Frequency of Colorectal Cancer in Male and Female Endurance Athletes Between the Ages of 35 and 50
NCT05447923 Addressing Disparities in Colorectal Cancer Screening in Black and Underserved Phoenix Communities
NCT05694559 Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics
NCT05524428 Eliminating Barriers to Colorectal Cancer Screening Using Rapid Cycle Testing: A Pilot Study
NCT04582500 Virtual Colonoscopy Using Omnipaque as a Contrast Agent
NCT04705363 A Sociolinguistic-enabled Web Application to Develop Precision Health Intervention for African Americans
NCT05903885 A Cross-sectional Partnership to Improve Prevention
NCT06117241 Reducing Metabolic Dysregulation in Dyads
NCT06059963 A Prospective, Multi-center, Observational Study for Signal-C Test Evaluation
NCT05362344 Colorectal Cancer Screening in Cystic Fibrosis
NCT05396846 My Best GI Eating Study
NCT05246839 Informed Choice - Compass
NCT05410977 Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients, CORAL Study
NCT06022887 Time-Restricted Eating and Mindfulness-Based Stress Reduction to Reduce the Risk of Early-Onset Colorectal Cancer
NCT00843375 Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas
NCT04331535 The Genomic Medicine at VA Study
NCT04792684 Collection of Samples USOPTIVAL Study
NCT04825834 DNA Evaluation of Fragments for Early Interception - Lung Cancer Training Study (DELFI-L101 Study)
NCT05793593 A Study of Using Social Networks to Encourage Three Peers to Complete Screening for Colorectal Cancer
NCT05732623 Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer
NCT04973007 Comparison of Contrast Agents in Liver MR for the Detection of Hepatic Metastases
NCT01060371 Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias
NCT03789162 Blood and Stool Sample Collection in Subjects With a Diagnosis of Colorectal Cancer or Colorectal Lesion: Act Fast

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