Read about different genes that are linked to hereditary cancer, their associated risks and guidelines for screening, preventing and treating cancers in people with inherited mutations in these genes.
General information for people with inherited mutations
Both men and women can carry an inherited mutation in the gene.
People with an inherited mutation in have increased risk for certain cancers. See the Cancer Risk section for more information. There are guidelines for screening and prevention for certain cancers in people with a mutation. There also may be clinical trials available for people who test positive for a mutation. See our Risk Management section for more information about screening options in people with mutations.
People diagnosed with a mutation who have been diagnosed with cancer may qualify for specific treatment or clinical trials. Visit the Cancer Treatment section for more information about clinical trials for people with a mutation
The name stands for Checkpoint Kinase 2." The gene is located on chromosome 22. helps control how cells divide.
find-support
FORCE offers many peer support programs for people with inherited mutations.
- Our Message Boards allow people to connect with others who share their situation. Once you register, you can post on the Diagnosed With Cancer board to connect with other people who have been diagnosed.
- Our Peer Navigation Program will match you with a volunteer who shares your mutation and situation.
- Our moderated, private Facebook group allows you to connect with other community members 24/7.
- Check out our virtual and in-person support meeting calendar.
- Join one of our Zoom community group meeting:
- Caregivers
- LGBTQIA
- Men
- Meetings in American Sign Language
- Meetings in Spanish
- People of Color
- Previvors
- Young Previvors
- Survivors
- Young Survivors
updated: 03/12/2022
related-resources
The following resources focus on mutations.
- FORCE resources:
- Information: gene mutations
- Blog: Breast Cancer and a Mutation AT 28
- Blog: Thyroid Cancer and a Genetic Mutation
- Blog: Male Breast Cancer and a Mutation
- Blogs:
- XRAY category:
- Video: Get to Know FORCE's Community
- Video: Cancer Risks, Screening & Prevention for People w/ , , & Other Genes
- Resources from other organizations:
- Genetics Home Reference is a site from the U.S. Library of Medicine that provides consumer-friendly information about the effects of an mutation on people's health.
updated: 03/16/2022