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Hereditary Cancer and Genetic Testing

General information for people with inherited  mutations

Both men and women can carry a mutation in the gene.  

People with an inherited mutation in have an increased risk for certain cancers.  See our Cancer Risk section for more information. There are guidelines for screening and prevention for certain cancers in people with a mutation. Clinical trials may also be available for people who test positive for a mutation. See our Risk Management section for more information for screening and prevention recommendations for people with mutations. 

People diagnosed with a mutation who have been diagnosed with cancer may qualify for specific treatment or clinical trials. Visit the Cancer Treatment section for more information about clinical trials for people with a mutation.

There is a very rare and serious disorder called blepharocheilodontic (BCD) syndrome that has been infrequently associated with mutations.  See our Other Considerations section for more information about this disorder.

The name stands for "Cadherin 1." The gene is located on chromosome 16.  helps cells stick to one another to form tissues and organs. 

Last updated September 19, 2022

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Get Support

FORCE offers many peer support programs for people with inherited mutations. 

updated: 08/06/2022