CDH1: Options for Cancer Treatment
Cancer Treatment Options for People with Inherited CDH1 Mutations
Surgical decisions for women diagnosed with breast cancer
Because of the risk for a second breast cancer diagnosis, women who are diagnosed with breast cancer who test positive for an inherited mutation in CDH1 may choose bilateral mastectomy rather than lumpectomy and radiation. Mutation carriers who undergo mastectomy are less likely to develop a second breast cancer.
Women diagnosed with cancer who have not had a bilateral mastectomy should continue breast cancer screening as recommended by the guidelines.
Targeted therapies and other treatment options
Treatment options for people with a mutation depend on the type and of cancer. Currently there are no FDA-approved targeted therapies or guidelines developed specifically for treating cancer in people with a mutation. To learn more about standard of care treatment options for specific types of cancer, visit our section on Cancer Treatment by Cancer Type. People with cancer should talk with their doctor about testing to look for changes in the cancer which may affect their treatment options.
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