Read about different genes that are linked to hereditary cancer, their associated risks and guidelines for screening, preventing and treating cancers in people with inherited mutations in these genes.
General information for people with inherited mutations
Both men and women can carry a mutation in the gene.
Women who inherit a mutation have an increased risk of breast cancer. Research on whether inherited mutations increase the risk for other cancers has been inconsistent. See our Cancer Risk section for more information.
Currently, there is not enough evidence on how best to manage cancer risk in people with a mutation. See our Risk Management section for more information.
People with a mutation who have been diagnosed with cancer may qualify for specific treatments or clinical trials. Visit our Cancer Treatment section for more information about treatment options for people with a mutation.
The name stands for " Associated Ring Domain 1." is located on chromosome 2. The gene works with to repair damaged . Although the two genes work together, the effects of a mutation are different; people with a mutation do not have the same cancer risk as people with a mutation.
find-support
FORCE offers many peer support programs for people with inherited mutations.
- Our Message Boards allow people to connect with others who share their situation. Once registered, you can post on the Diagnosed With Cancer board to connect with other people who have been diagnosed.
- Our Peer Navigation Program will match you with a volunteer who shares your mutation and situation.
- Our moderated, private Facebook group allows you to connect with other community members 24/7.
- Check out our virtual and in-person support meeting calendar.
- Join one of our Zoom community group meetings:
- Caregivers
- LGBTQIA
- Men
- Meetings in American Sign Language
- Meetings in Spanish
- People of Color
- Previvors
- Young Previvors
- Survivors
- Young Survivors
updated: 08/06/2022