Relevant for: People with triple negative breast cancer, In portal: Breast Cancer


Relevance: Medium-High
Most relevant for: Women diagnosed with breast cancer at a young age
Study: Improving outcomes for young women with breast cancer: fertility and childbearing issues
Fertility issues and family planning decisions are prominent concerns for young women with breast cancer. This XRAYS looks at Dr. Ann Partridge’s presentation at the 2018 San Antonio Breast Cancer symposium. Her talk, “Breast cancer in young women: Understanding differences to improve outcomes," focused on initial findings from the Young Women's Breast Cancer Study. Dr. Partridge’s research continues in the currently enrolling POSITIVE trial which tests whether women can safely interrupt adjuvant endocrine therapy in order to get pregnant. (1/7/19)
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Relevance: Medium-High
Most relevant for: Nigerian women or women of Nigerian descent who have breast cancer
Study: Inherited breast cancer in Nigerian women
A new study shows that among Nigerian women, one in eight cases of breast cancer is due to an inherited mutation in BRCA1, BRCA2, PALB2 or TP53. (12/5/18)
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Relevance: High
Most relevant for: People who are a member of a racial or ethnic minority group
Article: The importance of racial diversity in clinical trials
This article by journalists Caroline Chen and Riley Wong looks at racial disparities between participation in clinical trials and the population of people with cancer. (11/6/18)
Este artículo está disponible en español.
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Relevance: High
Most relevant for: Young women diagnosed with breast cancer who have not yet had genetic testing
Study: Surgeon attitude impacts rate of genetic testing after a breast cancer diagnosis
A study in JAMA Surgery this year examined the factors that impact genetic testing after a breast cancer diagnosis. This study suggests that the attitudes of attending surgeons about genetic testing have the most impact on whether patients receive testing. (10/6/18)
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Relevance: Medium-High
Most relevant for: People diagnosed with breast cancer who would benefit from increased activity and from eating more vegetables
Study: Gardening improves health outcomes for breast cancer patients
Research has shown that adopting a healthier lifestyle may improve overall health and outcomes for cancer survivors. This study looked at a 1-year home-based gardening intervention to increase activity and wellbeing among breast cancer survivors. (08/31/18)
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Relevance: Medium-High
Most relevant for: People diagnosed with triple-negative breast cancer
Study: Study identifies genes associated with risk of triple-negative breast cancer
Panel testing can identify women who are at increased risk for breast cancer. However, those at risk for triple-negative breast cancer cannot easily be identified because other than BRCA1, genes that increase the risk for triple-negative breast cancer are unknown. A new study uses panel testing to identify which genes increase the risk for triple-negative breast cancer. (8/23/18)
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Relevance: Medium-High
Most relevant for: People with advanced cancers
Study: Immunotherapy may lead to long-term remission of metastatic breast cancer
Metastatic breast cancer is often difficult to treat. In a new approach, called adoptive cell therapy (ACT), a patient’s own T-cells (a type of cancer-fighting immune cells) are collected, multiplied in a lab, and then returned to the patient. The goal is to enhance the patient’s immune system with many more T-cells that recognize and attack metastasized tumor cells. This study reports on a single patient whose metastatic breast cancer is still in remission (no evidence of disease) after more than 22 months following ACT. (8/16/18)
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Relevance: High
Most relevant for: People diagnosed with breast cancer
Article: High health insurance deductibles can interfere with breast cancer treatment decisions
A New York Times article published on May 4, 2018 examines the impact of high insurance deductibles on breast cancer treatment. (7/12/18)
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Relevance: High
Most relevant for: Women who have had or are considering mastectomy without reconstruction
Personal Story: Juliet's story: No reconstruction is a post-mastectomy option
In a March 2018 article from breastcancercare.org, Juliet conveys her personal experience with a breast cancer diagnosis and her decision to not have her breasts reconstructed after her mastectomy. She details the emotional complexity of her thought process and the empowerment she felt in her decisions. (5/24/18)
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Relevance: Medium
Most relevant for: Cancer patients who will be, or have recently undergone surgery
Study: Metastasis is affected by wound healing and inflammation in study on mice
This study in mice looked at how wound healing after surgery affects metastasis. Researchers found that wound healing caused changes in the mouse immune system that allowed some cancer cells to grow, but that treatment with a non-steroidal anti-inflammatory drug (NSAID) reduced inflammation and frequency of metastases. While this research is promising, it remains to be seen if similar effects occur in humans. (5/17/18)
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