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Search Results: Prevention, Detection & Risk (4 results)

1 through 4 of 4
Prostate Cancer Genetic Risk Evaluation and Screening Study (PROGRESS)

Prevention
People at high risk for prostate cancer due to an inherited mutation

Prostate Cancer Genetic Risk Evaluation and Screening Study (PROGRESS)

This study will look at how enhanced prostate cancer screening using MRI will improve early detection rates and further understanding of how inherited mutations can lead to development of prostate cancer.

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Men at High Genetic Risk for Prostate Cancer

Prevention

Men at High Genetic Risk for Prostate Cancer

The National Cancer Institute has opened a clinical trial for prostate cancer screening in men who are at high risk for prostate cancer due to an inherited mutation. This is trial is for men without prostate cancer, ages 30 to 75, who have tested positive for Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) or BRCA1, BRCA2, HOXB13, NBN, TP53, CHEK2, PALB2, RAD51C RAD51D, BRIP1, FANCA or ATM mutation. The trial involves screening MRI of the prostate every two years and biopsy of the prostate if the MRI is abnormal. There is no cost for travel or study-related tests.

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Blood Markers of Early Pancreas Cancer

Prevention

Blood Markers of Early Pancreas Cancer

The purpose of this study is to try to find markers of early pancreatic cancer for screening for individuals at higher-than-average risk, expedite the diagnosis in individuals with symptoms, and substantially improve an individual's chance of surviving the disease.

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Screening for Pancreatic Cancer in Patients with an Inherited BRCA1, BRCA2, PALB2 or ATM Mutation

Prevention

Preliminary Evaluation of Screening for Pancreatic Cancer in Patients with an Inherited Genetic Risk Due to a BRCA1, BRCA2, PALB2 or ATM Mutation

Improved screening for pancreatic cancer in high-risk groups, such as people with an inherited BRCA1, BRCA2, ATM, or PALB2 mutation, may help find cancer early and improve survival rates. People enrolled in this study will undergo screening using endoscopic ultrasound or MRI of the abdomen.

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Additional Results on Clinicaltrials.gov Prevention, Detection & Risk + PALB2
2 results
Clinical Trial Official Title
NCT02478892 Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk
NCT03568630 Blood Markers of Early Pancreas Cancer

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