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A New Drug, DT2216, Combined With Paclitaxel for Recurrent Platinum-Resistant Ovarian Cancer

Clinicaltrials.gov identifier:
NCT06964009

Treatment
Treatment study for people with recurrent platinum-resistant ovarian cancer

Phase 1

Multi-Cancer Detection Blood Tests in Adults Without Cancer: Vanguard Study

Clinicaltrials.gov identifier:
NCT06995898

Prevention
A study testing two multi-cancer detection blood tests in people who do not have cancer

A Study of the Drug Romosozumab in People With Metastatic Breast Cancer and Osteoporosis

Clinicaltrials.gov identifier:
NCT07776613

Quality of Life
Study for people with metastatic breast cancer and osteoporosis

Phase 2

VIRTUAL

Family Study for People with Certain Rare BRCA1 or BRCA2 Variants

Surveys, Registries, Interviews
Family study for adults with a known rare BRCA1 or BRCA2 variant in themselves or a relative

Psilocybin Therapy in Advanced Cancer

Clinicaltrials.gov identifier:
NCT05398484

Quality of Life
Study for people with advanced cancer

Phase 2

Comparing Treatment with Sacituzumab Govitecan and Bevacizumab to Chemotherapy and Bevacizumab for Recurrent Ovarian Cancer After PARP Inhibitor Maintenance Therapy

Clinicaltrials.gov identifier:
NCT07504588

Treatment
Study for platinum-sensitive ovarian cancer that has progressed after PARP inhibitor

Phase 2

VIRTUAL

A 5-minute Patient and Caregiver survey to share experiences with immunotherapy and any short-term or long-term side effects

Surveys, Registries, Interviews
This 5-minute survey allows cancer patients on immunotherapy (currently or in the past) and their caregivers to share their experiences, including their side effects and whether they were resolved or not.

Study of Dostarlimab Immunotherapy in People with Mismatch Repair-Deficient Endometrial Cancer Who Wish to Preserve Fertility

Clinicaltrials.gov identifier:
NCT04165772

Treatment
Treatment study for people with MSI-H or dMMR early-stage endometrial cancer.

Phase 2

VIRTUAL

The FYI on MRI: A Decision Support Intervention for Screening Breast MRI for Black and Latina Women

Clinicaltrials.gov identifier:
NCT06892275

Surveys, Registries, Interviews
Feedback survey on materials about breast MRI

A Study to Learn About the Study Medicine Called PF-07248144 in Combination with Fulvestrant in People with HR-positive, HER2-negative Advanced or Metastatic Breast Cancer who Progressed After a Prior Line of Treatment

Clinicaltrials.gov identifier:
NCT07062965

Treatment
Study for adults with advanced/metastatic HR-positive, HER2-negative breast cancer who have progressed from prior treatment

Phase 3

Comparing Shorter vs. Standard Radiation for High-Risk Prostate Cancer (High Five)

Clinicaltrials.gov identifier:
NCT05946213

Treatment
Treatment study for high-risk prostate cancer

Phase 3

VIRTUAL

PREVAIL Study: A Genetic Education and Genetic Testing Study for African American Men with Prostate Cancer or with a Strong Family History of Cancer

Prevention
Genetic testing for African American men with prostate cancer or cancer in the family

Testing the Drug CX-5461 for Treating Metastatic Solid Tumors

Clinicaltrials.gov identifier:
NCT06606990

Treatment
Phase 1 study for treatment of advanced solid tumors

Phase 1

VIRTUAL

Virtual ACT and Compassion-Based Group Therapy for Cancer-Related Well-Being

Clinicaltrials.gov identifier:
NCT06246955

Quality of Life
Adults with solid tumors or blood cancers who are receiving care at Mayo Clinic in AZ and experiencing stress or challenges related to cancer

Using the Drug Daraxonrasib in Surgically Removed Pancreatic Cancer (RASolute 304)

Clinicaltrials.gov identifier:
NCT07252232

Treatment
Study for pancreatic cancer treatment after surgery and chemotherapy

Phase 3

Comparing Daraxonrasib With or Without Chemotherapy to Chemotherapy Alone for First-Line Treatment of Metastatic Pancreatic Cancer (Rasolute 303)

Clinicaltrials.gov identifier:
NCT07491445

Treatment
Study for First-Line Treatment of Metastatic Pancreatic Cancer

Phase 3

Testing a Targeted Therapy ETX-19477 to Treat Advanced Solid Tumors in People with a BRCA2 Mutation (ERADIC8)

Clinicaltrials.gov identifier:
NCT06395519

Treatment
Treatment study for people with advanced breast, colorectal, endometrial, ovarian or pancreatic cancer

Phase 1/2

Evaluating the Safety of Nipple Sparing Mastectomy in Women With a High Risk for Breast Cancer

Clinicaltrials.gov identifier:
NCT06888388

Prevention
Study for people considering double mastectomy to reduce breast cancer risk