Featured Studies Results
An Early Detection and Prevention Study for People with an Increased Risk of Cancer (InAdvance)
https://www.facingourrisk.org/research-clinical-trials/study/385 /an-early-detection-and-prevention-study-for-people-with-an-increased-risk-of-cancer-inadvance
Clinicaltrials.gov identifier:
NCT05463796 (https://clinicaltrials.gov/show/NCT05463796)
Prevention
Study for people at risk of cancer, including previvors, survivors and family members
Genetic Testing for Cancer Risk for Black Families in Texas
https://www.facingourrisk.org/research-clinical-trials/study/396 /genetic-testing-for-cancer-risk-for-black-families-in-texas
Clinicaltrials.gov identifier:
NCT05694559 (https://clinicaltrials.gov/show/NCT05694559)
Prevention
Study to improve genetic counseling and testing to Black families in Texas
Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction
https://www.facingourrisk.org/research-clinical-trials/study/395 /low-dose-tamoxifen-with-or-without-omega-3-fatty-acids-for-breast-cancer-risk-reduction
Clinicaltrials.gov identifier:
NCT06195306 (https://clinicaltrials.gov/show/NCT06195306)
Prevention
Phase 2 study for overweight postmenopausal women at increased risk for breast cancer
Comparing an Experimental Drug Puxi-Sam to Standard Chemotherapy for Metastatic Endometrial Cancer (Bluestar‑Endometrial01)
https://www.facingourrisk.org/research-clinical-trials/study/370 /comparing-an-experimental-drug-puxi-sam-with-standard-chemotherapy-for-metastatic-endometrial-cancer-bluestarendometrial01
Clinicaltrials.gov identifier:
NCT07044336 (https://clinicaltrials.gov/show/NCT07044336)
Treatment
Phase 3 treatment study for metastatic endometrial cancer
Comparing a New Drug, Palazestrant, to Standard Treatment for Advanced Breast Cancer
https://www.facingourrisk.org/research-clinical-trials/study/387 /comparing-a-new-drug-palazestrant-to-standard-treatment-for-advanced-breast-cancer
Clinicaltrials.gov identifier:
NCT06016738 (https://clinicaltrials.gov/show/NCT06016738)
Treatment
Phase 3 study for ER-positive, HER2-negative advanced or metastatic breast cancer
Perceptions of Gastric Cancer Risk and Attitudes Toward Endoscopic Surveillance in People with CDH1 or CTNNA1 Mutations
https://www.facingourrisk.org/research-clinical-trials/study/390 /perceptions-of-gastric-cancer-risk-and-attitudes-toward-endoscopic-surveillance-in-people-with-cdh1-or-ctnna1-mutations
Surveys, Registries, Interviews
Online survey about gastric cancer risk and medical decision-making for people with an inherited CDH1 or CTNNA1 pathogenic variant
Testing a KRAS Vaccine with Immunotherapy for Advanced Pancreatic and Colorectal Cancers with MMR‑Proficient (MMR‑p) Tumors
https://www.facingourrisk.org/research-clinical-trials/study/384 /testing-a-kras-vaccine-with-immunotherapy-for-advanced-pancreatic-and-colorectal-cancer
Clinicaltrials.gov identifier:
NCT06411691 (https://clinicaltrials.gov/show/NCT06411691)
Treatment
Phase 1b treatment study for previously-treated pancreatic or colorectal cancer with a KRAS mutation
A Study of Fallopian Tube Removal with Delayed Ovary Removal to Lower Ovarian Cancer Risk (TUBA-WISP-II)
https://www.facingourrisk.org/research-clinical-trials/study/404 /
Clinicaltrials.gov identifier:
NCT04294927 (https://clinicaltrials.gov/show/NCT04294927)
Prevention
Prevention study for women at high risk for ovarian cancer
Testing a Combination of Immunotherapy and a Vaccine in People With Advanced Pancreatic or Lung Cancer
https://www.facingourrisk.org/research-clinical-trials/study/373 /testing-a-combination-treatment-with-an-anti-cd38-antibody-kras-vaccine-and-anti-pd-1-antibody-in-people-with-advanced-pancreatic-or-lung-cancer
Clinicaltrials.gov identifier:
NCT06015724 (https://clinicaltrials.gov/show/NCT06015724)
Treatment
Phase 2 treatment study for advanced pancreatic and lung cancer
Investigating Factors Impacting Time to Diagnosis Among Ovarian Cancer Patients Before and After Seeking Healthcare
https://www.facingourrisk.org/research-clinical-trials/study/391 /investigating-factors-impacting-time-to-diagnosis-among-ovarian-cancer-patients-prior-to-and-after-seeking-healthcare
Surveys, Registries, Interviews
Online survey for people diagnosed with ovarian cancer
Comparing Hormone Therapy With and Without Chemotherapy for Premenopausal Breast Cancer (OFSET)
https://www.facingourrisk.org/research-clinical-trials/study/388 /comparing-hormone-therapy-with-and-without-chemotherapy-for-premenopausal-breast-cancer-ofset
Clinicaltrials.gov identifier:
NCT05879926 (https://clinicaltrials.gov/show/NCT05879926)
Treatment
Phase 3 study for premenopausal, early-stage, ER positive, HER2-negative breast cancer
Treating Recurrent dMMR or MSI-High Endometrial Cancer with the Immunotherapy Drug, Nivolumab with or without the Immunotherapy Drug, Ipilimumab
https://www.facingourrisk.org/research-clinical-trials/study/362 /testing-an-immunotherapy-drug-nivolumab-with-or-without-the-immunotherapy-drug-ipilimumab-for-recurrent-dmmr-endometrial-cancer
Clinicaltrials.gov identifier:
NCT05112601 (https://clinicaltrials.gov/show/NCT05112601)
Treatment
Phase 2 treatment study for recurrent endometrial cancer with dMMR or MSI-High biomarker
Using a Shorter Type of MRI as a Screening Tool for People at High Risk for Prostate Cancer
https://www.facingourrisk.org/research-clinical-trials/study/353 /using-biparametric-magnetic-resonance-imaging-mri-as-a-screening-tool-for-those-at-high-risk-for-prostate-cancer
Clinicaltrials.gov identifier:
NCT05384535 (https://clinicaltrials.gov/show/NCT05384535)
Prevention
Screening for people at high risk for prostate cancer
The Prostate Cancer, Genetic Risk, and Equitable Screening Study (ProGRESS)
https://www.facingourrisk.org/research-clinical-trials/study/360 /the-prostate-cancer-genetic-risk-and-equitable-screening-study-progress
Clinicaltrials.gov identifier:
NCT05926102 (https://clinicaltrials.gov/show/NCT05926102)
Prevention
Prostate cancer screening study for male US veterans age 55–69
Understanding Access to Genetic Services for Latina Women with Breast Cancer
https://www.facingourrisk.org/research-clinical-trials/study/367 /understanding-access-to-genetic-services-for-latina-women-with-breast-cancer
Surveys, Registries, Interviews
A phone survey for Latina breast cancer survivors diagnosed within the past five years in California
Treating Advanced Breast Cancer or Other Solid Cancers Using a Combination of a New Targeted Therapy, ZEN003694, With The Targeted Therapy Abemaciclib (Verzenio)
https://www.facingourrisk.org/research-clinical-trials/study/363 /testing-a-new-drug-zen003694-with-chemotherapy-abemaciclib-for-people-with-advanced-or-inoperable-breast-cancer-and-other-solid-tumors
Clinicaltrials.gov identifier:
NCT05372640 (https://clinicaltrials.gov/show/NCT05372640)
Treatment
Phase 1 treatment study for advanced breast cancer and other solid tumors
Study of a New Drug, Sacituzumab Tirumotecan, Given Alone or in Combination with an Immunotherapy for Metastatic, Triple-Negative Breast Cancer (TroFuse-011)
https://www.facingourrisk.org/research-clinical-trials/study/359 /study-of-a-new-drug-sacituzumab-tirumotecan-given-alone-or-in-combination-with-an-immunotherapy-for-people-with-triple-negative-breast-cancer
Clinicaltrials.gov identifier:
NCT06841354 (https://clinicaltrials.gov/show/NCT06841354)
Treatment
Phase 3 treatment study for people with metastatic, triple-negative breast cancer
Study of a New Investigational Inhibitor to Treat People with Advanced Solid Tumors
https://www.facingourrisk.org/research-clinical-trials/study/300 /study-of-a-new-investigationai-inhibitor-to-treat-people-with-advanced-solid-tumors
Clinicaltrials.gov identifier:
NCT05932862 (https://clinicaltrials.gov/show/NCT05932862)
Treatment
Treatment study for people with advanced solid tumors
About FORCE
FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.