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APC: Other Considerations
Learn about other health implications for people with FAP or AFAP due to an APC mutation. Stay up to date by signing up for our community newsletter.
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APC: The Basics
APC: Gene Mutations and Cancer Risks
APC: Options for Managing Cancer Risk
APC: Options for Cancer Treatment
APC: Other Considerations
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Other Considerations for People with FAP and AFAP
Because of the high lifetime risk and early onset of medical issues, people of reproductive age with FAP may wish to speak with a genetics expert to discuss fertility options. There are options using assisted reproduction technology and preimplantation genetic diagnosis to select embryos that are free of an in the gene.
About 30% of people who test positive for an mutation did not inherit the mutation from either parent. These are known as de novo mutations. A person with a de novo mutation in the gene can pass the mutation on to their children.
Last updated March 26, 2025