Other Considerations for People with FAP and AFAP
Because of the high lifetime risk and early onset of medical issues, people of reproductive age with FAP may wish to speak with a genetics expert to discuss fertility options. There are options using assisted reproduction technology and preimplantation genetic diagnosis to select embryos that are free of an in the APC gene.
About 30% of people who test positive for an APC mutation did not inherit the mutation from either parent. These are known as de novo mutations. A person with a de novo mutation in the APC gene can pass the mutation on to their children.