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FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
Showing 1 through 10 out of 42

Relevance: High

Most relevant for: People with metastatic castration-resistant prostate cancer

Study: Combination treatment for metastatic castration-resistant prostate cancer may be especially effective for people with BRCA1 or BRCA2 mutations

This review summarizes the results of the TALAPRO2 study. It looked at how well the PARP inhibitor Talzenna (talazoparib) works for treating metastatic castration-resistant prostate cancer (mCRPC). Talzenna appears to be most effective for people with BRCA1 or BRCA2 mutations but is also effective for people with certain other mutations. (posted 9/30/25)

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Relevance: Medium-High

Most relevant for: People newly diagnosed with early-stage breast cancer who have BRCA1 or BRCA2 mutations

Study: Breast cancer treatment combination and dose improves survival in people with inherited BRCA1 and BRCA2 mutations

Treatment before surgery with a combination of targeted therapy and chemotherapy resulted in longer survival for people with an inherited BRCA1 or BRCA2 mutation who have early-stage breast cancer. The study evaluated a new dosing strategy that made it possible to safely combine Lynparza (olaparib) and chemotherapy (carboplatin). (Posted 8/31/25)

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Relevance: High

Most relevant for: People with unresectable or metastatic colorectal cancer that is MSI-High or dMMR

Study: Two immunotherapy drugs are better than one for some metastatic colorectal cancers

Combining two immunotherapy drugs is a more effective treatment for certain metastatic colorectal cancers than using either treatment drug alone. Used together, Opdivo (nivolumab) plus Yervoy (ipilimumab) slowed cancer growth in MSI-High metastatic colorectal cancers, a type of colorectal cancer often found in Lynch syndrome. The FDA approved this combined treatment for MSI-High metastatic colorectal cancer after progression with chemotherapy. (Posted 4/30/25)

Este artículo está disponible en español

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Relevance: Medium-High

Most relevant for: Young women with breast cancer concerned about survivorship issues

Topic: Addressing the needs of young adults with breast cancer

This update addresses common concerns faced by young adults with breast cancer, particularly fertility and childbearing, psychosocial health and treatment-related side effects. (Posted 2/28/25)

Este artículo está disponible en español.

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Relevance: Medium-High

Most relevant for: People with cancer interested in using cannabis to help manage symptoms.

Study: Use of cannabis for cancer symptom management

Among people with cancer, interest in the use of cannabis to manage cancer symptoms and treatment side effects is high. The world's leading professional organization of oncologists has published strategies to help adults with cancer and their healthcare providers have open, nonjudgmental discussions about the use of cannabis to manage cancer symptoms. (Posted 9/27/24)

Este artículo está disponible en español.

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Relevance: Medium-High

Most relevant for: People with advanced endometrial cancer

Study: Managing the side effects of advanced endometrial cancer treatment

Immunotherapy plus targeted therapy is a treatment option for advanced endometrial cancer that has progressed after prior treatment. People who start the two-drug combination are more likely to have a positive experience if they learn about the possible side effects and when they might occur. The most common side effects and how to manage them are discussed in this review. (Posted 9/25/24)

Este artículo está disponible en español.

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Relevance: Medium

Most relevant for: People with prostate cancer

Update: News from the FDA: First-line treatment and biosimilars for prostate cancer

The FDA recently approved a first-line treatment for non-metastatic, castration-sensitive prostate cancer. Approval was also given to two new drugs known as biosimilars that can be used in place of two already approved biologics to prevent bone weakening, pain or fractures that may occur from certain hormone therapies or from cancer that has spread to the bone. (Posted 9/10/24)

Este artículo está disponible en español.

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Relevance: High

Most relevant for: People diagnosed with cancer

Topic: Acupressure for cancer symptom relief

Acupressure is a safe treatment that can be used to relieve some symptoms of cancer and side effects of treatment. Light pressure applied to key points on the body may help with fatigue, sleep, nausea and possibly other symptoms as well. (Posted 8/1/24)

Este artículo está disponible en español.

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Relevance: Medium-High

Most relevant for: Cancer patients

Topic: Experts call for early palliative care for cancer patients

People with cancer need support and care not only at the end of life but from the time of diagnosis. At the 2024 American Society of Clinical Oncology (ASCO) annual meeting, the organization’s president urged cancer healthcare professionals to make palliative care central to cancer treatment. (Posted 7/17/24)

Este artículo está disponible en español.

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Relevance: Medium-High

Most relevant for: Gay and bisexual men diagnosed with prostate cancer

Topic: Sexual health concerns of gay and bisexual men with prostate cancer

Prostate cancer therapy can affect gay and bisexual men differently than heterosexual men. Many urologists do not routinely address these unique concerns. Selecting providers who understand the concerns that are unique to gay and bisexual patients and asking questions about sexual health concerns may improve these patients' healthcare experiences. (Posted 9/21/23)

Este artículo está disponible en español.

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