FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you.
XRAY is a reliable source of hereditary cancer research-related news and information.
Learn more about the XRAY program
Breast Cancer
Relevance: Medium-Low
Strength of Science: Medium-High
Research Timeline: Lab Research
Study : Hot chili pepper component slows growth and kills laboratory-grown breast cancer cells
Relevance: Medium-Low
Strength of Science: Medium-High
Research Timeline: Lab Research
Most relevant for: This research is not relevant to people yet
Finding new treatments that target triple-negative breast cancer is an area of great interest. An early step in developing these treatments is learning more about the biology of tumor in the laboratory. This study looked at how capsaicin, the spicy component of chili peppers, might work with a protein found in many cancers, including triple-negative breast cancer, to stop cancer cell growth. This is the first step in a long process towards developing new treatments for triple-negative breast cancer. (2/14/17)
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Relevance: Medium-High
Strength of Science: Medium-High
Research Timeline: Post Approval
Study : A step in the development of a new breast cancer risk assessment tool for Hispanic women
Relevance: Medium-High
Strength of Science: Medium-High
Research Timeline: Post Approval
Most relevant for: Hispanic women
Current tools used to calculate breast cancer risk make their estimations based on data from non-Hispanic white women and may not accurately predict breast cancer risk in women of other races and ethnicities. With further testing, a new risk assessment tool developed specifically for Hispanic women could more accurately predict breast cancer risk in women who do not have mutations in BRCA or other genes associated with hereditary breast cancer. (02/07/17)
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Study : “Chemobrain” seen in breast cancer patients up to six months after treatment
Most relevant for: People diagnosed with breast cancer who have or will be treated with chemotherapy
Many people report memory or concentration problems, commonly known as “chemobrain,” during and after cancer treatment. New research shows that for some breast cancer patients these issues continue 6 months after treatment. Documentation of this well-known effect is a crucial first step in developing ways to limit and treat it. (02/02/17)
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Relevance: Medium-High
Strength of Science: Medium
Research Timeline: Human Research
Study : Does prior antidepressant use affect the treatment breast cancer patients receive?
Relevance: Medium-High
Strength of Science: Medium
Research Timeline: Human Research
Most relevant for: Women diagnosed with breast cancer who have received antidepressants
Previous research found an association between depression and survival in breast cancer patients, but the reasons for this association are unclear. Researchers in this study found that women who had been previously prescribed antidepressants were less likely to receive breast cancer treatment that followed national guidelines than those who had not. Although the difference was small, it underscores the need for patients to discuss any history of depression with their health care providers. (1/24/17)
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Relevance: Medium-High
Strength of Science: Medium
Study : Women with breast cancer symptoms but no lump may wait longer to seek medical care
Relevance: Medium-High
Strength of Science: Medium
Most relevant for: People with breast cancer symptoms
Some patients take longer than others before getting a potential breast cancer checked by their health care provider. Believing that women who have breast cancer symptoms but have no lump may wait longer, researchers in this study used data from women who were diagnosed with breast cancer in 2009 and 2010 to identify possible explanations. (1/18/17)
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Relevance: Medium-High
Strength of Science: Medium
Research Timeline: Human Research
Study : High vitamin D levels at breast cancer diagnosis may be associated with a better prognosis
Relevance: Medium-High
Strength of Science: Medium
Research Timeline: Human Research
Most relevant for: Women at average risk for breast cancer and newly diagnosed women
Vitamin D is most known for its role in maintaining bone health but vitamin D has additional roles in keeping us healthy. In this study, researchers found that breast cancer patients who had the highest amounts of vitamin D in their blood (slightly over the recommended levels) had better health outcomes, including overall survival, than women with lower amounts of vitamin D. This finding adds to the growing evidence for the role of vitamin D in cancer, but it does not change how breast cancer is prevented or treated. (1/10/17)
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Study : Angelina Jolie spoke out on BRCA testing: Did genetic testing increase?
Most relevant for: People interested in genetic testing for an inherited mutation
Angelina Jolie published an editorial in the New York Times in 2013 about her choice to have a double mastectomy after finding out she was positive for a BRCA1 mutation. Researchers from a recent study claim that her celebrity endorsement of BRCA testing may have missed its target audience (previvors), due to the increase in BRCA testing following publication of the editorial but a decrease in the number of mastectomies performed. However, the study failed to take into account that many women without breast cancer do not pursue mastectomy in the months following genetic testing. (1/4/17)
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Article : After mastectomy: reconstruct or not?
Most relevant for: Woman who are facing mastectomy
Today, more women know they can have breast reconstruction after removing their breasts for cancer treatment or risk reduction. But what about choosing not to undergo reconstruction? Roni Caryn Rabin writes about the experiences of women who decide against reconstruction in her New York Times piece “‘Going Flat’ After Breast Cancer.” (12/14/16)
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Relevance: Medium
Quality of Writing: Medium-Low
Article : Headlines claim drug combination destroys tumor in 11 days—is this too good to be true?
Relevance: Medium
Quality of Writing: Medium-Low
Most relevant for: People with Her2-positive breast cancer
A recent IFLScience headline proclaimed "Remarkable Breast Cancer Trial Destroys Tumors in Just 11 Days." This sounds amazing but it leaves out key facts. First, the finding applies only to HER2-positive breast cancer, not all breast cancers. More importantly, the results are from a conference presentation and have not yet appeared in a peer-reviewed scientific journal. What does that mean for breast cancer patients? (12/6/16)
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Relevance: Medium-High
Quality of Writing: Medium
Personal Story : Men get breast cancer too
Relevance: Medium-High
Quality of Writing: Medium
Most relevant for: Men diagnosed with breast cancer
Cathy Free's piece for People, “Men Have Breasts Too: New York Man Who Survived Stage 2 Breast Cancer Spreads Message,” tells the stories of two men whose experiences with breast cancer inspired them to speak openly about breast cancer awareness for men. (11/29/16)
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