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Treatment

A Study to Learn About the Study Medicine Called PF-07248144 in Combination with Fulvestrant in People with HR-positive, HER2-negative Advanced or Metastatic Breast Cancer who Progressed After a Prior Line of Treatment

Clinicaltrials.gov identifier:
NCT07062965

Treatment
Phase 3 study for adults with advanced/metastatic HR-positive, HER2-negative breast cancer who have progressed from prior treatment

Comparing Daraxonrasib With or Without Chemotherapy to Chemotherapy Alone for First-Line Treatment of Metastatic Pancreatic Cancer (Rasolute 303)

Clinicaltrials.gov identifier:
NCT07491445

Treatment
Phase 3 Study for First-Line Treatment of Metastatic Pancreatic Cancer

Treating Advanced MSI-High or dMMR Cancers Using the Targeted Therapy MOMA-341 Given Alone or In Combination with Standard Therapies

Clinicaltrials.gov identifier:
NCT06974110

Treatment
Treatment study for people with advanced or metastatic cancers

Comparing Shorter vs. Standard Radiation for High-Risk Prostate Cancer (High Five)

Clinicaltrials.gov identifier:
NCT05946213

Treatment
Phase 3 treatment study for high-risk prostate cancer

Using the Drug Daraxonrasib in Surgically Removed Pancreatic Cancer (RASolute 304)

Clinicaltrials.gov identifier:
NCT07252232

Treatment
Phase 3 study for pancreatic cancer treatment after surgery and chemotherapy

Study of a New Oral Medication, Daraxonrasib After Surgery to Help Prevent Pancreatic Cancer from Returning

Clinicaltrials.gov identifier:
NCT07252232

Treatment
Phase 3 treatment trial for pancreatic cancer that was removed by surgery

Comparing Two Vaccine Treatments With Immunotherapy for Pancreatic Cancer Before and After Surgery

Clinicaltrials.gov identifier:
NCT06782932

Treatment
Phase 1b/2 treatment study for newly diagnosed pancreatic cancer that can be removed with surgery and who have not yet received treatment

Treating Advanced Endometrial Cancer with Targeted Therapies (ComboMATCH)

Clinicaltrials.gov identifier:
NCT05554328

Treatment
Phase 2 treatment study for recurrent endometrial cancer

NePtune: Using PARP Inhibitors Before Surgery in Localized Prostate Cancer

Clinicaltrials.gov identifier:
NCT05498272

Treatment
Treatment study for people with intermediate- or high-risk prostate cancer with certain tumor mutations

Using a Blood Test to Detect Early Cancer Recurrence After Treatment (ORACLE)

Clinicaltrials.gov identifier:
NCT05059444

Treatment
Post-treatment study to monitor for recurrence

Comparing an Experimental Drug Puxi-Sam with Standard Chemotherapy for Metastatic Endometrial Cancer (Bluestar‑Endometrial01)

Clinicaltrials.gov identifier:
NCT07044336

Treatment
Phase 3 treatment study for metastatic endometrial cancer

Treating Advanced Solid Tumors with Targeted Therapies Called RAS(ON) Inhibitors Combined With the Targeted Immunotherapy Ivonescimab

Clinicaltrials.gov identifier:
NCT07397338

Treatment
Phase 1/2 treatment study for solid tumors with a RAS mutation

Comparing a New Drug, Palazestrant, to Standard Treatment for Advanced Breast Cancer

Clinicaltrials.gov identifier:
NCT06016738

Treatment
Phase 3 study for ER-positive, HER2-negative advanced or metastatic breast cancer

Treating Advanced Solid Tumors with a KRAS G12C Mutation Using Targeted Therapies Called RAS(ON) Inhibitors

Clinicaltrials.gov identifier:
NCT06128551

Treatment
Phase 1/2 treatment study for advanced colorectal, pancreatic or lung cancer with a KRAS G12C mutation

Testing a KRAS Vaccine with Immunotherapy for Advanced Pancreatic and Colorectal Cancers with MMR‑Proficient (MMR‑p) Tumors

Clinicaltrials.gov identifier:
NCT06411691

Treatment
Phase 1b treatment study for previously-treated pancreatic or colorectal cancer with a KRAS mutation

Comparing Hormone Therapy With and Without Chemotherapy for Premenopausal Breast Cancer (OFSET)

Clinicaltrials.gov identifier:
NCT05879926

Treatment
Phase 3 study for premenopausal, early-stage, ER positive, HER2-negative breast cancer