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Treatment

A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone or Darolutamide (TALENT)

Clinicaltrials.gov identifier:
NCT06844383

Treatment
Phase 2 study for metastatic castration-resistant prostate cancer with an HRR mutation

A Study to Learn About the Study Medicine Called PF-07248144 in Combination with Fulvestrant in People with HR-positive, HER2-negative Advanced or Metastatic Breast Cancer who Progressed After a Prior Line of Treatment

Clinicaltrials.gov identifier:
NCT07062965

Treatment
Phase 3 study for adults with advanced/metastatic HR-positive, HER2-negative breast cancer who have progressed from prior treatment

A New Drug, DT2216, Combined With Paclitaxel for Recurrent Platinum-Resistant Ovarian Cancer

Clinicaltrials.gov identifier:
NCT06964009

Treatment
Phase 1b study for people with recurrent platinum-resistant ovarian, fallopian tube, or primary peritoneal cancer

Treating Advanced MSI-High or dMMR Cancers Using the Targeted Therapy MOMA-341 Given Alone or In Combination with Standard Therapies

Clinicaltrials.gov identifier:
NCT06974110

Treatment
Treatment study for people with advanced or metastatic cancers

A Phase 2 Study of Dostarlimab Immunotherapy in People with Mismatch Repair-Deficient Endometrial Cancer Who Wish to Preserve Fertility

Clinicaltrials.gov identifier:
NCT04165772

Treatment
Phase 2 treatment study for people with MSI-H or dMMR early-stage endometrial cancer.

Comparing Shorter vs. Standard Radiation for High-Risk Prostate Cancer (High Five)

Clinicaltrials.gov identifier:
NCT05946213

Treatment
Phase 3 treatment study for high-risk prostate cancer

Testing the Drug CX-5461 for Treating Metastatic Solid Tumors

Clinicaltrials.gov identifier:
NCT06606990

Treatment
Phase 1 study for treatment of advanced solid tumors

Using the Drug Daraxonrasib in Surgically Removed Pancreatic Cancer (RASolute 304)

Clinicaltrials.gov identifier:
NCT07252232

Treatment
Phase 3 study for pancreatic cancer treatment after surgery and chemotherapy

Comparing Daraxonrasib With or Without Chemotherapy to Chemotherapy Alone for First-Line Treatment of Metastatic Pancreatic Cancer (Rasolute 303)

Clinicaltrials.gov identifier:
NCT07491445

Treatment
Phase 3 Study for First-Line Treatment of Metastatic Pancreatic Cancer

Testing a Targeted Therapy ETX-19477 to Treat Advanced Solid Tumors in People with a BRCA2 Mutation (ERADIC8)

Clinicaltrials.gov identifier:
NCT06395519

Treatment
Phase 1/2 treatment study for people with advanced breast, colorectal, endometrial, ovarian or pancreatic cancer

Study of a New Oral Medication, Daraxonrasib After Surgery to Help Prevent Pancreatic Cancer from Returning

Clinicaltrials.gov identifier:
NCT07252232

Treatment
Phase 3 treatment trial for pancreatic cancer that was removed by surgery

Comparing Two Vaccine Treatments With Immunotherapy for Pancreatic Cancer Before and After Surgery

Clinicaltrials.gov identifier:
NCT06782932

Treatment
Phase 1b/2 treatment study for newly diagnosed pancreatic cancer that can be removed with surgery and who have not yet received treatment

Using a Blood Test to Detect Early Cancer Recurrence After Treatment (ORACLE)

Clinicaltrials.gov identifier:
NCT05059444

Treatment
Post-treatment study to monitor for recurrence

Comparing an Experimental Drug Puxi-Sam with Standard Chemotherapy for Metastatic Endometrial Cancer (Bluestar‑Endometrial01)

Clinicaltrials.gov identifier:
NCT07044336

Treatment
Phase 3 treatment study for metastatic endometrial cancer

Treating Advanced Solid Tumors with Targeted Therapies Called RAS(ON) Inhibitors Combined With the Targeted Immunotherapy Ivonescimab

Clinicaltrials.gov identifier:
NCT07397338

Treatment
Phase 1/2 treatment study for solid tumors with a RAS mutation

Study of a New Targeted Therapy Given Alone or in Combination with an Immunotherapy for Metastatic, Triple-Negative Breast Cancer

Clinicaltrials.gov identifier:
NCT06841354

Treatment
Phase 3 treatment study for people with metastatic, triple-negative breast cancer