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Categories Cancer Risk

FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
Showing 1 through 10 out of 144

Relevance: Medium-High

Most relevant for: People who have had or are considering liquid biopsy testing

Topic: What Patients Need to Know About Liquid Biopsies in Cancer Care

Liquid biopsies are tests that look for signs of cancer in blood or other body fluids. These signs can include cancer cells that have broken away from a tumor, pieces of cancer cell DNA and proteins or other biomarkers found in cancer cells. Liquid biopsies can be used to screen for cancer before a cancer diagnosis or guide treatment after a diagnosis. (posted 2/6/26)

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Relevance: High

Most relevant for: Men and women diagnosed with breast cancer who have a BRCA1 or BRCA2 mutation

Study: Understanding the risks of a second cancer after a breast cancer diagnosis in people with BRCA1 and BRCA2 mutations

After breast cancer, people who have a BRCA1 or BRCA2 mutation face a greater risk of a second cancer compared to individuals without a BRCA mutation. This study helps to better understand this risk so that breast cancer survivors with mutations can receive informed, personalized plans for surveillance and follow-up care. (Posted 12/11/25)

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Relevance: Medium

Most relevant for: People concerned about their risk of pancreatic cancer

Study: Bacteria and fungi in the mouth may help identify those at risk for pancreatic cancer

Pancreatic cancer often grows quickly and is usually discovered at a later stage. A better understanding of risk factors, like changes in bacteria found in the mouth, could provide doctors with early warning signs needed to help them diagnose and treat cancer sooner. The results of this study suggest that changes in bacteria and fungi in your mouth may help identify people who are at higher risk of pancreatic cancer. (Posted 11/24/25)

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Relevance: Medium-High

Most relevant for: Women with a BRCA1 or BRCA2 mutation who have a uterus.

Study: Study: Endometrial cancer risk for people with BRCA1 and BRCA2 mutations

This study looked at how often endometrial cancer occurred in people with BRCA1 or BRCA2 mutations to better understand how BRCA mutations affect the risk of endometrial cancer. The researchers also asked whether known risk factors for endometrial cancer impact the frequency of endometrial cancer in people with BRCA1 or BRCA2 mutations. Findings from the study highlight the importance of shared conversations between patients and providers regarding risk monitoring and preventive options. (posted 10/7/25)

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Relevance: High

Most relevant for: Families with a known MLH1 mutation

Study: Cancer may occur at earlier ages in later generations of families with Lynch syndrome

In families with Lynch syndrome mutations, cancer may occur at an earlier age with each generation. This study looked at the effect called anticipation in families with MLH1-associated Lynch syndrome. (Posted 10/3/25)

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Relevance: Medium-High

Most relevant for: People with breast cancer or at high-risk of breast cancer

Update: FDA in the News: FDA approvals and health information on breast cancer

This XRAY review reports new treatments approved by the FDA for early and metastatic breast cancer and educational resources about women's health. (Posted 8/4/25)

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Relevance: Medium-High

Most relevant for: People with BRCA mutation who have textured breast implants

Study: Possible link between BRCA1 and BRCA2 mutations and rare breast implant-associated lymphoma

The causes of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), a rare cancer that develops near implants, are unknown. Results from this study suggest that people with an inherited mutation in BRCA1 or BRCA2 may be at increased risk for BIA-ALCL. However, because very few cases of BIA-ALCL occurred among participants, more research is needed to confirm or refute this finding. (Posted 7/14/2025)

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Relevance: Medium-High

Most relevant for: People of Hispanic ancestry who have pancreatic cancer or have a family history of cancer

Study: Hereditary pancreatic cancer among people of Hispanic ancestry in Mexico

This study looks at people of Mexican ancestry who have pancreatic cancer to identify mutations linked to hereditary cancer. Knowledge of a hereditary cancer mutation can inform patients and their family members about the need for additional surveillance or different treatment options. Access to genetic testing in Mexico is more limited than in the United States. This study emphasizes the importance of genetic testing for inherited cancer risk in pancreatic cancer patients in Mexico. (posted 6/25/25)

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Relevance: High

Most relevant for: People with hereditary pancreatic cancer risk or strong family history of pancreatic cancer

Study: Impact of mental healthcare among those with increased pancreatic cancer risk

Pancreatic cancer is often aggressive and diagnosed at a late stage, which can lead to uncertainty and fear. For those at risk due to a genetic mutation or family history, access to surveillance and mental health support is essential to help manage the emotional impact.  (Posted 5/12/25)

Este artículo está disponible en español 

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Relevance: Medium

Most relevant for: People with multiple myeloma or who have families with multiple myeloma

Study: Hereditary cancer mutations among people with multiple myeloma

People with multiple myeloma who have inherited gene mutations are more likely to have had another cancer previously and may respond better to certain treatments than people with multiple myeloma who do not have inherited mutations. Individuals with an inherited BRCA1 and BRCA2 mutation may have a slightly increased risk for multiple myeloma, but more research is needed to confirm this. (Posted 4/23/25)

Este artículo está disponible en español 

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