All XRAYs
Relevance: Medium-High
Most relevant for: People with ER-positive, HER2-negative advanced breast cancer with ESR1 mutations
Study: Treating advanced breast cancer with ESR1 mutations shows promise
Treatment with the new hormonal drug camizestrant benefited people with certain advanced breast cancers with a biomarker called an ESR1 mutation. People who participated in the SERENA6 study experienced a longer time before their cancer worsened and had a better quality of life than those who received the standard treatment. This study used a blood test to track changes in the cancer to clarify whether treatment worked before symptoms developed. (posted 2/19/26)
READ MORE ›
Relevance: High
Most relevant for: People with metastatic prostate cancer
Update: News from the FDA: Updates on metastatic prostate cancer treatment
This update highlights recent FDA approvals and expanded uses for three drugs related to metastatic prostate cancer treatment. These updates affect how prostate cancer may be found and treated, including new options that may allow some men with advanced prostate cancer to delay or avoid chemotherapy. Overall, these updates may provide more choices for people with metastatic castration-resistant prostate cancer (mCRPC) and metastatic castration-sensitive prostate cancer (mCSPC). (posted 2/13/26)
READ MORE ›
Relevance: High
Most relevant for: People diagnosed with cancer who require 5-FU or capecitabine treatment
Guideline: FDA recommends testing to prevent serious side effects from 5-FU and capecitabine chemotherapy
A small number of people treated with the chemotherapy drugs 5-FU (5-fluorouracil) or capecitabine (Xeloda) can have serious or even life-threatening side effects because their body breaks down the drug more slowly than is typical. A genetic test called DPYD testing can help identify people at higher risk for serious side effects before treatment starts. (posted 2/11/26)
READ MORE ›
Relevance: Medium-High
Most relevant for: People who have had or are considering liquid biopsy testing
Topic: What Patients Need to Know About Liquid Biopsies in Cancer Care
Liquid biopsies are tests that look for signs of cancer in blood or other body fluids. These signs can include cancer cells that have broken away from a tumor, pieces of cancer cell DNA and proteins or other biomarkers found in cancer cells. Liquid biopsies can be used to screen for cancer before a cancer diagnosis or guide treatment after a diagnosis. (posted 2/6/26)
READ MORE ›
Relevance: Medium-High
Most relevant for: People who have early-stage triple-negative breast cancer and an inherited mutation in BRCA1 or BRCA2
Study: Treating triple-negative breast cancer in people with inherited BRCA1 or BRCA2 mutations
This review summarizes two studies highlighted during the 2025 San Antonio Breast Cancer Symposium. Both studies focus on targeted therapy and immunotherapy given before surgery to treat early-stage triple-negative breast cancer in people with inherited BRCA1 or BRCA2 mutations. One study evaluated pre-surgery treatment with Zejula and Jemperli; the other study evaluated Lynparza and Imfinzi. (posted 2/3/26)
READ MORE ›
Relevance: High
Most relevant for: Men and women diagnosed with breast cancer who have a BRCA1 or BRCA2 mutation
Study: Understanding the risks of a second cancer after a breast cancer diagnosis in people with BRCA1 and BRCA2 mutations
After breast cancer, people who have a BRCA1 or BRCA2 mutation face a greater risk of a second cancer compared to individuals without a BRCA mutation. This study helps to better understand this risk so that breast cancer survivors with mutations can receive informed, personalized plans for surveillance and follow-up care. (Posted 12/11/25)
READ MORE ›
Relevance: Medium-High
Most relevant for: People with a high risk for pancreatic or colon cancer
Study: Early trial of new vaccine shows promise for treating KRAS-mutated pancreatic and colon cancers
A vaccine for treating pancreatic and colon cancers with a biomarker known as a KRAS mutation produced a strong immune response in people at high risk of recurrence in an early clinical trial. This promising vaccine is now being studied in a larger clinical trial. (Posted 12/9/25)
READ MORE ›
Relevance: Medium
Most relevant for: People concerned about their risk of pancreatic cancer
Study: Bacteria and fungi in the mouth may help identify those at risk for pancreatic cancer
Pancreatic cancer often grows quickly and is usually discovered at a later stage. A better understanding of risk factors, like changes in bacteria found in the mouth, could provide doctors with early warning signs needed to help them diagnose and treat cancer sooner. The results of this study suggest that changes in bacteria and fungi in your mouth may help identify people who are at higher risk of pancreatic cancer. (Posted 11/24/25)
READ MORE ›
Relevance: High
Most relevant for: People with an inherited mutation in ATM, BRCA1, BRCA2, CHEK2, PALB2 or a Lynch syndrome gene who have been diagnosed with breast, colorectal or pancreatic cancer
Study: Cancer patients with certain inherited mutations have cancer outcomes similar to those without inherited mutations
People with an inherited mutation in certain genes, including ATM, CHEK2, PALB2, BRCA or Lynch syndrome genes, have an increased risk of cancer. In this study, researchers wanted to know whether cancer patients with inherited mutations had a different chance of survival than patients without an inherited mutation in these genes. These results showed that, although the risk of cancer is increased, there is no difference in survival after a diagnosis of breast, pancreatic or colorectal cancer with or without these genetic changes. (posted 11/20/25)
READ MORE ›
Relevance: High
Most relevant for: People diagnosed with early colon cancer
Study: Exercise may delay the return of colon cancer and help people live longer
People who participated in a structured exercise program following completed treatment for colon cancer experienced more time without cancer growth and lived longer than those who did not. This study suggests that regular, moderate-intensity exercise can benefit the long-term health of people with early-stage colon cancer. (Posted 11/05/25)
READ MORE ›