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Categories Cancer Treatment

FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
Showing 1 through 10 out of 138

Relevance: Medium-High

Most relevant for: People with breast cancer or at high-risk of breast cancer

Update: FDA in the News: FDA approvals and health information on breast cancer

This XRAY review reports new treatments approved by the FDA for early and metastatic breast cancer and educational resources about women's health. (Posted 8/4/25)

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Relevance: Medium-High

Most relevant for: People with advanced, unresectable, or metastatic pancreatic cancer or NSCLC

Study: FDA approves new targeted therapy for advanced pancreatic cancer

A new treatment called Bizengri has been approved by the FDA for patients with advanced or metastatic pancreatic cancer. This treatment targets pancreatic cancer or non-small cell lung cancers that have a rare tumor mutation called an NRG1 fusion. (Posted 7/24/25)

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Relevance: High

Most relevant for: People with advanced or metastatic breast cancer with a PIK3CA tumor mutation.

Study: New FDA approval of Itovebi, a drug that may improve treatment for certain advanced or metastatic breast cancers

About one-third of hormone receptor-positive (HR-positive), HER2-negative metastatic breast cancers have a PIK3CA tumor mutation that can increase cancer growth and lead to treatment resistance. A new targeted therapy, Itovebi (inavolisib), improved patient outcomes when combined with standard treatment. This led to the recent FDA approval of the drug. (Posted 7/3/25)

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Relevance: High

Most relevant for: People with HR-positive metastatic breast cancer

Study: Enhertu shows promising results for HER2-low and HER2-ultralow metastatic breast cancer

Recent study results show that a new targeted treatment works better than standard chemotherapy for people with metastatic hormone receptor-positive breast cancers with low or ultralow HER2 status. (Posted 5/15/25)

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Relevance: High

Most relevant for: People with unresectable or metastatic colorectal cancer that is MSI-High or dMMR

Study: Two immunotherapy drugs are better than one for some metastatic colorectal cancers

Combining two immunotherapy drugs is a more effective treatment for certain metastatic colorectal cancers than using either treatment drug alone. Used together, Opdivo (nivolumab) plus Yervoy (ipilimumab) slowed cancer growth in MSI-High metastatic colorectal cancers, a type of colorectal cancer often found in Lynch syndrome. The FDA approved this combined treatment for MSI-High metastatic colorectal cancer after progression with chemotherapy. (Posted 4/30/25)

Este artículo está disponible en español

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Relevance: Medium-High

Most relevant for: People with colorectal cancer or at risk of colorectal cancer

Update: News from the FDA: Colorectal cancer screening and treatment

This XRAY review is a summary of FDA colorectal cancer (CRC) updates in the last year, including education regarding CRC screening, three treatment drugs targeting different types of CRC and two colorectal screening tests. (Posted 4/16/25)

Este artículo está disponible en español

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Relevance: Medium-High

Most relevant for: Premenopausal women before or during early breast cancer treatment

Update: Ovarian suppression may reduce breast cancer recurrence

Ovarian suppression—blocking estrogen production in the ovaries—can improve breast cancer outcomes in premenopausal women. This review provides information about ovarian suppression and describes who might benefit. (Posted 3/6/25)


Este artículo está disponible en español.

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Relevance: Medium-High

Most relevant for: Young women with breast cancer concerned about survivorship issues

Topic: Addressing the needs of young adults with breast cancer

This update addresses common concerns faced by young adults with breast cancer, particularly fertility and childbearing, psychosocial health and treatment-related side effects. (Posted 2/28/25)

Este artículo está disponible en español.

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Relevance: Medium

Most relevant for: People with an inherited mutation in CDKN2A

Article: Life with a high-risk pancreatic and melanoma cancer mutation

One woman seeks genetic testing after her sister died of pancreatic cancer. Despite how her family’s mutation in the CDKN2A gene resulted in multiple cancer diagnoses and deaths and a suspicious finding during her own pancreatic cancer screening, Amarensia Spruitenburg shares a message of hope and gratitude. By telling her story, Amarensia highlights the impact that hereditary cancer can have on families.  (Posted 11/22/24)

Este artículo está disponible en español.

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Relevance: Medium-High

Most relevant for: People with endometrial cancer

Update: News from the FDA: New endometrial cancer approvals

The FDA recently approved three new immunotherapy treatments (Jemperli, Imfinzi and Keytruda) for advanced endometrial cancer. (Posted 11/7/24)

Este artículo está disponible en español.

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