Education > XRAY > Endometrial Cancer

FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
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Relevance: High

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Strength of Science: Medium-High

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Research Timeline: Post Approval

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Study : Genetic testing for inherited mutations may be helpful for all people with advanced or metastatic cancer

Most relevant for: People with metastatic or recurrent cancer

In a study of nearly 12,000 cancer patients with a variety of cancers, eight percent of participants with metastatic cancer had an inherited mutation in a cancer gene that qualified them for a targeted treatment approved by the FDA or for participation in a clinical trial. The majority of people with metastatic cancer were unaware that they had an inherited mutation, and had not receive gene-directed treatment to which their tumor may have responded. The study authors suggest that genetic testing for inherited mutations may be warranted for all patients with advanced or metastatic cancer. (posted 9/30/21)

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Genetic testing for inherited mutations may be helpful for all people with advanced or metastatic cancer

Relevance: Medium-Low

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Research Timeline: Human Research

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Update : Liquid biopsies for cancer screening, monitoring and treatment

Most relevant for: People considering a liquid biopsy to screen for cancer

Could a simple blood test change cancer detection, treatment and monitoring? Several companies are offering a type of blood test known as a liquid biopsy to detect multiple cancers at their earliest stages, monitor response to treatment and help choose the best treatment. Although progress has been made using liquid biopsies to treat cancer, these tests have not yet been shown to detect cancer early enough to save lives. (posted 9/29/21)

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Liquid biopsies for cancer screening, monitoring and treatment

Relevance: Medium-High

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Quality of Writing: High

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Article : Transgender peoples' perspectives of being diagnosed with gender-associated cancer

Most relevant for: transgender people

An ABC News article provides viewpoints and data that conveys the added stress experienced by transgender and gender-nonconforming people when they are diagnosed with gender-associated cancer (e.g., ovarian or prostate cancer) that does not match their gender identity. (posted 9/13/21)

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Transgender peoples' perspectives of being diagnosed with gender-associated cancer

Relevance: High

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Strength of Science: High

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Research Timeline: Post Approval

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Study : Birth control pills may offer long-term protection against endometrial and ovarian cancer

Most relevant for: People concerned about endometrial, ovarian or breast cancer risk

A large study showed that birth control pills may protect against endometrial and ovarian cancers, even years after use was discontinued. (posted 6/1/21)

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Birth control pills may offer long-term protection against endometrial and ovarian cancer

Relevance: High

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Strength of Science: Medium-High

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Research Timeline: Post Approval

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Update : Immunotherapy dostarlimab gains FDA approval for treatment of recurrent and advanced endometrial cancer

Most relevant for: People with recurrent or advanced endometrial cancer

The FDA has given accelerated approval for the immunotherapy agent dostarlimab (Jemperli) to treat recurrent and advanced endometrial cancer that has a biomarker called mismatch repair deficiency (dMMR). This adds a new treatment option for people with recurrent or advanced endometrial cancer. (posted 5/18/21)

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Immunotherapy dostarlimab gains FDA approval for treatment of recurrent and advanced endometrial cancer

Relevance: High

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Strength of Science: High

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Research Timeline: Post Approval

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Study : Daily high-dose aspirin taken for at least 2 years reduces the risk of colorectal cancer but not other cancers in people with Lynch syndrome

Most relevant for: People with Lynch syndrome

Research has shown that daily aspirin use can reduce the risk of colon and other cancers. The Cancer Prevention Program 2 (CaPP2) study looked at the effect of daily aspirin in patients with Lynch syndrome. After 10 years of follow-up, the results showed that taking daily aspirin for two years reduced the frequency of colon cancer in patients with Lynch syndrome, and importantly, did not result in an increase in side-effects or complications. No benefit was seen for other Lynch syndrome-related cancers, including endometrial cancer. (5/17/21)

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Daily high-dose aspirin taken for at least 2 years reduces the risk of colorectal cancer but not other cancers in people with Lynch syndrome

Relevance: Medium-High

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Strength of Science: Medium-High

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Research Timeline: Post Approval

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Study : Body Mass Index (BMI) may affect how well aspirin use protects against colorectal and ovarian cancer

Most relevant for: People concerned about their risk of colorectal or ovarian cancer.

This study looked at the impact of daily aspirin use for lowering the risk for multiple types of cancers and whether this risk reduction can be modified by cancer risk factors such as obesity, smoking, physical inactivity or a family history of cancer. (3/19/21)

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Body Mass Index (BMI) may affect how well aspirin use protects against colorectal and ovarian cancer

Relevance: Medium-High

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Research Timeline: Post Approval

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Guideline : COVID vaccines for people with cancer

Most relevant for: Cancer patients, their family and caregivers

Should cancer patients get a COVID vaccine? The National Comprehensive Cancer Network (NCCN) and the American Society of Clinical Oncology (ASCO) provide guidance for people with cancer. These experts recommend that most cancer patients get vaccinated as soon as the vaccine is offered (unless they are allergic to a vaccine component). Cancer patients who have had recent surgery may delay vaccination a few days after surgery. Those with a suppressed immune system are advised to delay getting the vaccine until they’re healthy enough to do so. (2/1/21)

Este artículo está disponible en español.

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COVID vaccines for people with cancer

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