Education > XRAY > Colorectal Cancer

FORCE's eXaming the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
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Relevance: High

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Strength of Science: High

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Research Timeline: Post Approval

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Study : Immunotherapy drug Keytruda received FDA approval and showed benefit for treatment of colorectal cancer

Most relevant for: People with advanced colorectal cancer and a type of biomarker called MSI-High (MSI-H)

In June 2020, the FDA approved Keytruda (pembrolizumab) as an initial therapy for advanced colorectal cancer. This approval was based on the results from the KEYNOTE-177 study. In this study, Keytruda was more successful than chemotherapy in delaying progression of certain types of colorectal cancers. (11/25/20)

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Immunotherapy drug Keytruda received FDA approval and showed benefit for treatment of colorectal cancer

Topic : COVID-19 and Cancer

Most relevant for: People in treatment for cancer, or people scheduled for surgery

The current COVID-19 pandemic has led to many changes in our communities. In this XRAY review we focus on the intersection between COVID-19 and cancer: who may be immunosuppressed, coping with changes in surveillance or treatment, and evaluating and dealing with media. (4/13/20)

Este artículo está disponible en español.

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COVID-19 and Cancer

Relevance: Medium-High

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Strength of Science: Medium-High

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Research Timeline: Human Research

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Study : Cancer risk associated with inherited mutations in Lynch syndrome genes

Most relevant for: People with Lynch syndrome mutations

Lynch syndrome is the most common inherited cause of cancer affecting about 1 in 300 people. People with Lynch syndrome have an increased risk of colorectal endometrial and other cancers. A large study followed people with mutations in the Lynch syndrome genes MLH1, MSH2, MSH6 and PMS2 to determine the risk of other types of cancer. (2/21/20)

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Cancer risk associated with inherited mutations in Lynch syndrome genes

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