Testing the Drug Obeticholic Acid for Familial Adenomatous Polyposis

https://www.facingourrisk.org/research-clinical-trials/study/289/testing-the-drug-obeticholic-acid-for-familial-adenomatous-polyposis

Clinicaltrials.gov identifier:
NCT05223036 (https://clinicaltrials.gov/show/NCT05223036)

Prevention study for people with an APC mutation and FAP or AFAP who have polyps in remaining tissue after colectomy surgery

This study is no longer enrolling patients.

What the Study Involves

Participants will be divided into two groups:

Group 1 will receive OCA for 6 months
Group 2 will receive a placebo for 6 months

All participants will undergo GI endoscopy with biopsy and collection of blood samples at screening and on study.

After completion of the study treatment, patients are followed within 14-21 days.

This Study is Open To:

This study is no longer enrolling patients.

This Study is Not Open To:

This study is no longer enrolling patients.

About FORCE

FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.