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Awareness of Fertility Preservation Options in Patients Affected by Cancer


Online anonymous survey for adults treated in the US for cancer

Exploring Awareness of Fertility Preservation Options in Patients at Risk of Iatrogenic Infertility. Role of Genetic Counselors

To explore patients' awareness of how medical treatments may affect fertility and identify helpful resources for future patients through a 10-15 minutes anonymous online survey. Enrollment ends on February 28,2025. Eligibility: Adults treated in the US for cancer, thalassemia, or sickle cell disease.

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PATROL Study: Prostate Cancer Screening for People AT Genetic Risk FOr Aggressive Disease

Prevention
Screening study for people with a mutation linked to prostate cancer risk

PATROL Study: Prostate Cancer Screening for People AT Genetic Risk FOr Aggressive Disease

The PATROL (Prostate Cancer Screening for People AT Genetic Risk FOr Aggressive Disease) study is for people at risk for prostate cancer because they carry one or more genes that are known or suspected to increase prostate cancer risk: BRCA2, HOXB13, ATM, BRCA1, MLH1, MSH2, MSH6, PALB2, PMS2, CHEK2, RAD51D, or TP53.

Clinicaltrials.gov identifier: NCT04472338
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Vaccines for Pancreatic Cancer  After Chemotherapy


Treatment study for people with pancreatic cancer

Vaccines for Pancreatic Cancer After Chemotherapy

This study is looking at the safety of, and the immune system response to a vaccine in people diagnosed with pancreatic cancer. The vaccine will  be administered after chemotherapy. The vaccine will incorporate proteins that can trigger an immune response and will be given along with a drug called poly-ICLC which can also activate immune cells.

Clinicaltrials.gov identifier: NCT05111353
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Denosumab for Breast Cancer Risk Reduction in Women With an Inherited BRCA1 Mutation (The Breast Cancer Prevention Study)


Prevention study enrolling women ages 25-55 with a BRCA1 mutation

Denosumab for Breast Cancer Risk Reduction in Women With an Inherited BRCA1 Mutation (The Breast Cancer Prevention Study)

This is a study to test the effectiveness of a drug (denosumab) on preventing the development of breast cancer in women with an inherited BRCA1 mutation.

Denosumab is a drug that is currently used to treat bone loss in order to reduce the risk of broken bones in healthy people, and is also used to reduce new bone growths in cancer patients whose cancer has spread to their bones. Research has shown that denosumab may also reduce the risk of developing breast cancer in women with an inherited BRCA1 mutation.

Clinicaltrials.gov identifier: NCT04711109
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Social Support and Coping Strategies Among LGBTQIA+ Cancer Patients

Surveys, Registries, Interviews
This study explores how different levels of support systems influence coping strategies among LGBTQIA+ cancer patients

Social Support and Coping Strategies Among LGBTQIA+ Cancer Patients

This study explores how different levels of support systems influence coping strategies among LGBTQIA+ cancer patients, specifically patients who are over the age of 18, actively diagnosed with cancer, and reside in the United States.

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Understanding the Cancer Journey: A Survey of Patient Experiences and Emotional Impact

Surveys, Registries, Interviews
Online survey for people diagnosed with breast, colorectal, gastric or prostate cancer within the past twenty years

Understanding the Cancer Journey: A Survey of Patient Experiences and Emotional Impact

Researchers are conducting a survey of cancer patients who were diagnosed with breast, colorectal, gastric or prostate cancer within the past twenty years. The aim is to gather information about their diagnosis, treatment, and personal experiences of battling cancer. The survey will collect data on the type of cancer, diagnosis, treatment plan, medications used, and personal stories throughout the journey to help gain a better understanding of the emotional and psychological impact of cancer on patients.

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Immunotherapy and PARP Inhibitor for Advanced or Metastatic Breast, Ovarian or Pancreatic Cancer with a BRCA Mutation


Treatment study for people with advanced breast, ovarian or pancreatic cancer and an inherited or tumor BRCA mutation

Combining the Immunotherapy Dostarlimab and PARP Inhibitor Niraparib for Advanced or Metastatic Breast, Ovarian or Pancreatic Cancer with an Inherited or Tumor BRCA Mutation

This study is looking at the effectiveness of combining a PARP inhibitor called niraparib and an immunotherapy called dostarlimab for treating people with an inherited BRCA mutation (found with genetic testing) or a tumor mutation (found through tumor testing) who have breast, pancreatic, ovarian, fallopian tube or primary peritoneal cancer that is metastatic or advanced and cannot be removed by surgery (unresectable).

Clinicaltrials.gov identifier: NCT04673448
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The DETECT Study: Detecting Endometrial Cancer in Tampons

Prevention
Early detection of endometrial cancer in women over 45 years of age who are undergoing hysterectomy surgery at the University of Alabama

The DETECT Study: Detecting Endometrial Cancer in Tampons

This study will test whether endometrial samples from tampons can be used for early detection of endometrial cancer and is open to women over 45 years of age who are undergoing hysterectomy surgery (surgery to remove the uterus)

Clinicaltrials.gov identifier: NCT03538665
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Effectiveness of Lymph Node Mapping to Reduce the Risk of Swelling in the Legs in Patients with Stage I Endometrial Cancer

Treatment
People with stage I endometrial cancer who are having a hysterectomy

Effectiveness of Lymph Node Mapping to Reduce the Risk of Swelling in the Legs in Patients with Stage I Endometrial Cancer

This study compares the effect of sentinel lymph node mapping to standard lymph node dissection in reducing the risk of swelling in the legs (lymphedema) in patients undergoing a hysterectomy for stage I endometrial cancer.

Clinicaltrials.gov identifier: NCT05646316
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Ethical Challenges and Best Practices in End-of-Life Care


Interview of palliative care patients and/or their adult family members who have been offered and involved in genetic testing or counseling

Ethical Challenges in Genetic Testing for Terminally Ill People and their Families

This study will interview palliative care patients and/or their adult family members (spouse, parents, children, siblings) who have been offered and involved in genetic testing or counseling related to the condition for which the patients are receiving palliative care.

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The LiFT UP Li-Fraumeni & TP53: Understanding & Progress Study

Surveys, Registries, Interviews
Study looking at cancer risk for people with Li-Fraumeni syndrome

The LiFT UP Li-Fraumeni & TP53: Understanding & Progress Study

The LiFT UP Study is a research project for individuals and families from around the world. The goal is to learn more about adults and children who have a change in the TP53 gene in their blood to better predict their specific cancer risks. 

Clinicaltrials.gov identifier: NCT04541654
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Registry to Discover New Treatments and Developmental Processes of Colorectal and Endometrial Cancer in Patients with Hereditary Cancer

Surveys, Registries, Interviews
Study to collect and save data, cancer samples, and cancer family health histories from people who screen for colorectal endometrial cancer

Registry to Discover New Treatments and Developmental Processes of Colorectal and Endometrial Cancer in Patients with Hereditary Cancer

This research registry will collect and save data, cancer samples and family health history information to discover new ways cancer develops. It will look to find new genes that could be used for treatments and preventing cancer for people with hereditary cancer.

Clinicaltrials.gov identifier: NCT06096688
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Roadmap to Parenthood: A Study about Fertility and Family-Building After Cancer


A survey for people aged 18-45, assigned female at birth, and history of a cancer diagnosis

Roadmap to Parenthood: A Study about Fertility and Family-Building After Cancer

Roadmap to Parenthood is a remote, survey-based study. Eligible participants must be aged 18-45, assigned female at birth, and history of a cancer diagnosis. this study to evaluate an online tool developed to educate and provide support to women and people assigned female at birth who are interested in family building after cancer. This study involves the completion of four online surveys. All study procedures are done remotely.

Clinicaltrials.gov identifier: NCT06050135
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New Treatment  in People with Triple Negative Breast Cancer or Advanced Solid Tumors

Treatment
Treatment study for people with triple negative breast cancer, advanced solid tumors or lymphomas

Study of a New Treatment Called ONM-501 Alone and in Combination with Immunotherapy for Triple Negative Breast Cancer, Advanced Solid Tumors and Lymphomas

Study of a new drug called ONM-501 for people with triple negative breast cancer, advanced solid tumors or lymphomas

Clinicaltrials.gov identifier: NCT06022029
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The Phoenix Trial: Cemiplimab for Patients with Localized dMMR Colon Cancer

Treatment
This study will examine how well Cemiplimab works for patients with localized colon cancer who have dMMR

The Phoenix Trial: Cemiplimab for Patients with Localized dMMR Colon Cancer

This study will examine the effectiveness and safety of cemiplimab, a treatment given prior to surgery. Participants will undergo endoscopy after the therapy and take CT scans to assess the effects of the therapy. The study also will compare genes of pretreatment cancer samples between patients who responded well to the therapy and patients who did not.

Clinicaltrials.gov identifier: NCT05961709
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Mastectomy Decision Support Study


Individual interviews with women who had or are considering a bilateral mastectomy to receive feedback on materials that inform about the emotional implications of the surgery

Mastectomy Decision Support Study

The purpose of this study is to get participants’ opinions on the content, format, and design of educational materials that inform about the emotional consequences of undergoing a bilateral mastectomy.

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ShareForCures®: Susan G. Komen's People-Powered, Data-Driven Breast Cancer Research Registry

Surveys, Registries, Interviews
Registry for anyone diagnosed with breast cancer

ShareForCures®: Susan G. Komen's People-Powered, Data-Driven Breast Cancer Research Registry

Today, researchers are learning about breast cancer from a small subset of patients, who are not representative of all breast cancer patients. ShareForCures® is an online registry that offers people who have been diagnosed with breast cancer a way to participate in research by connecting information about themselves with their breast cancer diagnosis, medical records, genomics. Participation is open to anyone adult, living in the United States, and who has been diagnosed with breast cancer.

Clinicaltrials.gov identifier: NCT05654246
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The Risk Factor Analysis of Hereditary Breast and Ovarian Cancer In Women with BRCA1, BRCA2 or PALB2 Mutations

Surveys, Registries, Interviews
Study for people who have a BRCA1, BRCA2, or PALB2 genetic mutation

The Risk Factor Analysis of Hereditary Breast and Ovarian Cancer In Women with BRCA1, BRCA2 or PALB2 Mutations

Those who carry the BRCA1, BRCA2 or PALB2 gene mutations experience a higher lifetime risk of developing breast and ovarian cancer, but we need to know more about the other genetic and non-genetic factors that may also influence risk. This study follows women with these gene mutations over time, striving to build the evidence we need to help them and others make better decisions to protect their health.

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Study of the Drug Sovilnesib in People with Ovarian Cancer

Treatment
Treatment study for people with platinum-resistant ovarian cancer

Study of the Drug Sovilnesib in People with Ovarian Cancer

This study will test the safety and effectiveness of the drug sovilnesib in patients with ovarian cancer.

Clinicaltrials.gov identifier: NCT06084416
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Treatment Studies for People with ER-Positive, HER2-Negative Advanced or Metastatic Breast Cancer (TACTIVE-U)


Treatment for ER-positive, HER2-negative metastatic breast cancer

Studies for People with ER-Positive, HER2-Negative Advanced or Metastatic Breast Cancer (TACTIVE-U)

Researchers at Pfizer and Arvinas are conducting the TACTIVE-U studies for people with ER-positive, HER2-negative advanced or metastatic breast cancer who have received at least one prior round of treatment and no more than two prior rounds of treatments for advanced or metastatic disease. One of these rounds of treatment must have included a CDK4/6 inhibitor (e.g., Kisqali, Verzenio, Ibrance). The TACTIVE-U studies are looking at the safety of an oral study medicine, ARV-471 (also known as vepdegestrant), and how well it works when combined with other breast cancer medicines.

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High Dose Testosterone Treatment for People with Metastatic Prostate Cancer and an ATM, CDK12 or CHEK2 Mutation

Treatment
People who have metastatic castration-resistant prostate cancer with an ATM, CDK12, or CHEK2 mutation

High Dose Testosterone Treatment for People with Metastatic Prostate Cancer and an ATM, CDK12 or CHEK2 Mutation

This study will examine how well an increased dose of testosterone treatment works for people with metastatic castration-resistant prostate cancer (mCRPC) with an ATM, CDK12, or CHEK2 genetic mutation. Participants will continue to receive the medication as long as their cancer doesn’t get worse and they do not experience severe side effects.

Clinicaltrials.gov identifier: NCT05011383
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Testing a Vaccine for Treating or Preventing Triple-Negative Breast Cancer


Treatment study for people with stage 2 or 3 triple-negative breast cancer at high risk for recurrence

Testing a Vaccine for Treating or Preventing Triple-Negative Breast Cancer

Researchers are studying the affects of this breast cancer vaccine on the immune system in two groups of people:

  • For people diagnosed with stage 2 or stage 3 triple-negative breast cancer at high risk for recurrence.
  • People with an inherited mutation in BRCA1, BRCA2, or PALB2 who are planning to undergo a risk-reducing mastectomy.
Clinicaltrials.gov identifier: NCT04674306
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UPLIFT: Cancer Caregivers Study


Survey for cancer caregivers of an LGBTQIA+ family member or friend

UPLIFT: Cancer Caregivers Study

Survey for cancer caregivers of an LGBTQIA+ family member or friend to understand the impact of caregiving on the mental, physical, and financial well-being of LGBTQ+ people providing unpaid care

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Screening Study for Men at High Genetic Risk for Prostate Cancer

Prevention
Prostate screening with MRI for men with Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) or a BRCA1, BRCA2, HOXB13, ATM, NBN, TP53, BRIP1, CHEK2, PALB2, RAD51C, RAD51D, or other mutation

Screening Study for Men at High Genetic Risk for Prostate Cancer

The National Institutes of Health has a clinical trial for men at high genetic risk for prostate cancer. This is trial is for men without prostate cancer, ages 30 to 75, who have tested positive for Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) or BRCA1, BRCA2, HOXB13, ATM, NBN, TP53, BRIP1, CHEK2, PALB2, RAD51C, RAD51D, or FANC (FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, and FANCM). The trial involves screening MRI of the prostate every two years and biopsy of the prostate if the MRI is abnormal. There is no cost for travel or study-related tests. 

Clinicaltrials.gov identifier: NCT03805919
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Young, Empowered & Strong: Web-Based Symptom Monitoring and Self-Management for Young Adult Breast Cancer Survivors


Women diagnosed with breast cancer between the ages of 15-39

Young, Empowered & Strong: Web-Based Symptom Monitoring and Self-Management for Young Adult Breast Cancer Survivors (YES Study)

The goal of this study is to measure whether a web-based patient-reported symptom monitoring and self management portal, Young, Empowered & Strong (YES), improves the quality of life of young breast cancer survivors when compared to standard of care symptom management. 

Clinicaltrials.gov identifier: NCT04906200
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Carboplatin Chemotherapy before Surgery for Patients with High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

Treatment
Treatment before surgery for people with high-risk prostate cancer and an inherited BRCA1 or BRCA2 gene mutation

Carboplatin Chemotherapy before Surgery for Patients with High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

This study tests how well carboplatin before surgery works in treating patients with high-risk prostate cancer who have inherited BRCA1 or BRCA2 gene mutations. The purpose of the study is to treat men with BRCA1 or BRCA2 mutations who are at higher risk of prostate cancer after surgery (removal of the prostate) compared to patients without these mutations.

Clinicaltrials.gov identifier: NCT05806515
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FORCE Survey for People at Increased Risk for Colorectal, Pancreatic or Prostate Cancer


Survey for people at high risk for Colorectal, Pancreatic or Prostate Cancer

FORCE Survey for People at Increased Risk for Colorectal, Pancreatic or Prostate Cancer

FORCE is conducting a short survey to better understand the unmet needs of people who are at high risk for colorectal, pancreatic or prostate cancer. You can take the survey here

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Using ctDNA for Earlier Detection and Treatment  of Recurrence or Spread after Treatment for Stage 3 Colon Cancer

Treatment
Monitoring and treatment study for people who completed treatment for stage 3 colon cancer

Using ctDNA Blood Test for Earlier Detection and Treatment of Recurrence or Spread after Treatment for Stage 3 Colon Cancer

The usual care after a person with stage 3 colon cancer has had surgery and chemotherapy is to begin active surveillance. This is a time when no additional treatment is given, but instead patients have frequent imaging scans to see if their cancer has come back.

This study is looking at whether a blood test known as circulating tumor DNA (ctDNA) can find signs of remaining cancer or recurrence after treatment earlier than standard active surveillance. People in the study who have evidence of cancer in their ctDNA test may receive additional treatment based on their test results. The goal of this study is to learn if using ctDNA and additional treatment improves outcomes in people after treatment for stage 3 colon cancer. Currently, testing with ctDNA is not part of standard of care to determine if colon cancer treatment was successful or if there is a recurrence. 

Clinicaltrials.gov identifier: NCT03803553
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Treatment of HER2-positive Colorectal Cancer as First Line Treatment in the Metastatic Setting

Treatment
People with HER2-positive colorectal cancer who have not yet received treatment in the metastatic setting

Comparing a Combination of Drugs for Treatment of HER2-positive Colorectal Cancer as First Line Treatment in the Metastatic Setting

This study is being done to decide if the drug Tukysa (Tucatinib) combined with other cancer drugs works better than the standard of care, which is chemotherapy treatment for people with a specific type of colorectal cancer called HER2 positive colorectal cancer. The study also aims to understand the side effects of the combination of these drugs in treatment. The combination of drugs being used are Tukysa (Tucatinib), Herceptin (Trastuzumab), and mFOLFOX6, which is a combination of Oxaliplatin, Leucovorin, Levoleucovorin, and Fluorouracil.

Clinicaltrials.gov identifier: NCT05253651
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Study of Colorectal Cancer and Genetics in Hispanic and Latino People (ENLACE Study)

Treatment
Hispanic and Latino people diagnosed with colorectal cancer

Study of Colorectal Cancer and Genetics in Hispanic and Latino People (ENLACE Study)

The ENLACE study will learn more about colorectal cancer in Hispanic people so that treatment can be improved. Results may help your doctor choose your treatment and help you find out if you are eligible for a clinical trial. Your results may also help family members understand their cancer risks. People will have blood drawn and complete a questionnaire to join the study. Genetic testing will be done on your blood and the tissue from your tumor biopsy or surgery to test the genes that you inherited. You do not have to pay for the genetic testing. You will receive the results of your test from your oncologist and genetic counseling may be recommended. Two weeks and one year after talking with your doctor about your test results, you will complete follow-up questionnaires either in person or over the phone. 

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Additional Results on Clinicaltrials.gov
1000 results
Clinical Trial Official Title
NCT05464082 Functional Precision Oncology to Predict, Prevent, and Treat Early Metastatic Recurrence of TNBC
NCT03161431 SX-682 Treatment in Subjects With Metastatic Melanoma Concurrently Treated With Pembrolizumab
NCT05806931 Sequential TAS-OX Alternating With TAS-IRI Plus Bevacizumab for Late-Line Metastatic Colorectal Cancer
NCT04771520 Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors
NCT05903131 A Behavioral Intervention to Promote Primary Prevention and Uterine Preservation in Premenopausal Women With Obesity and Endometrial Hyperplasia
NCT04886531 Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers
NCT03127631 A RAndomizeD Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients
NCT05961982 Evaluation of Endoscopic Ultrasound-Guided Radiofrequency Ablation for the Management of Pancreatic Tumors, ERASE Study
NCT06106282 Breast Cancer Survivors Who Experience Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS)
NCT05994482 Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study
NCT05825482 Breast Margin Study: Routine Cavity Shave Margins Vs. Selective Margins Using Savi Scout®
NCT06428682 Role of TXA in Patients Undergoing Breast Free Flap Reconstruction
NCT02451982 Platform Study of Neoadjuvant and Adjuvant Immunotherapy for Patients With Resectable Adenocarcinoma of the Pancreas
NCT06545331 Study of XB010 in Subjects With Solid Tumors
NCT05803382 Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers
NCT05669482 Study of Avutometinib (VS-6766) +Defactinib With Gemcitabine and Nab-paclitaxel in Patients With Pancreatic Cancer
NCT06636682 FK-PC101 as Adjuvant Therapy for Men With High-Risk Prostate Cancer
NCT04339374 Ultrasound and Photoacoustic Imaging for Enhanced Differential Diagnosis of Rectal Cancer
NCT06721065 A Study of Language Interpretation Solutions for People With Breast Cancer
NCT06904365 Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women
NCT06488365 In Vivo Liquid Biopsy of Melanoma (Cytophone)
NCT05585320 A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors
NCT04567420 DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)
NCT04471974 ZEN-3694, Enzalutamide, and Pembrolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer
NCT06610474 Evaluation of an Online Prostate Cancer Screening Decision Aid
NCT05933265 Study of LP-184 in Patients With Advanced Solid Tumors
NCT06297265 Manual Lymphatic Drainage Breast Massage in Breast Cancer Patients After Breast Conserving Surgery
NCT06295965 Clonal Hematopoiesis and Therapy-Emergent Myeloid Neoplasms in Patients With Cancers, CHANCES Study
NCT06639074 Folate Receptor Alpha Dendritic Cells (FRαDCs) or Placebo for the Treatment of Patients With Stage III or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer, FAROUT Trial
NCT06549465 Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer (CRPC)
NCT04074720 Prospective Breast Cancer Biospecimen Collection
NCT05764720 Stereotactic Adaptive Radiation Therapy of Borderline Resectable Pancreatic Cancer an Individualized Approach
NCT05902520 Adoptive Cell Therapy Using Cancer Specific CD8+ Tumor Infiltrating Lymphocytes in Adult Patients With Solid Tumors
NCT05931874 Optimizing a mHealth Physical Activity Intervention With Mindful Awareness Lessons in Breast Cancer Survivors
NCT03572374 Talking to Employers and Medical Staff About Breast Cancer Treatment and Your Job
NCT05579366 Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
NCT05800665 A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer
NCT04503265 A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies
NCT05592626 A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
NCT03769766 Trial of Curcumin to Prevent Progression of Low-risk Prostate Cancer Under Active Surveillance
NCT04198766 Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)
NCT06465966 UFPTI 2403-PR12: Real-Time Volumetric Ionizing Radiation Acoustic Imaging for In-vivo Proton Treatment Monitoring in Pencil-Beam Scanning
NCT05267626 Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer
NCT06376565 Improving Colonoscopy Surveillance for Patients with High Risk Colon Polyps
NCT06744465 NearWave Optical Molecular Monitoring
NCT03866382 Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
NCT06441474 Understanding and Addressing Rejection of Personalized Breast Cancer Risk Information in Women
NCT04756765 Talazoparib Monotherapy in PALB2 Mutation Associated Advanced Breast Cancer
NCT02749474 Maternal Cancer Diagnosis and Treatment During Pregnancy:a Database for Maternal, Fetal, and Neonatal Outcomes
NCT04959474 Pre-operative SABR With and Without Caloric Restriction for Early Stage Breast Cancer
NCT05305365 Study Assessing QBS72S For Treating Brain Metastases
NCT00756665 Prostate Active Surveillance Study
NCT05268666 A Study of Orally Administered JBI-802, an LSD1/HDAC6 Inhibitor, in Patients With Advanced Solid Tumors
NCT06268665 Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy
NCT05879926 Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
NCT06590857 Trial of 225Ac-DOTATATE (RYZ101) in Subjects with ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.
NCT05952557 An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)
NCT03558048 The Effect of IBD Flares on Serum PSA
NCT04904757 Contrast-enhanced Spectral Mammography (CESM) Breast Cancer Screening
NCT06402357 High Intensity Focused Ultrasound in Prostate Cancer
NCT05968157 MIRAI-MRI: Comparing Screening MRI for Patients at High Risk for Breast Cancer Identified by Mirai and Tyrer-Cuzick
NCT06130826 Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer
NCT06633926 Integrative Approaches for Cancer Survivorship (IACS3)
NCT03863457 [18F] F-GLN by PET/CT in Breast Cancer
NCT05990426 Alternate Day Fasting After Surgery for Patients Undergoing Chemotherapy
NCT06518057 Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer
NCT05183126 Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With Cancer
NCT02595957 Genomic Services Research Program
NCT06817226 BREAST Choice Decision Tool R21
NCT00830557 Collecting Medical Information and Tissue Samples From Patients With Pancreatic Cancer or Other Pancreatic Disorders
NCT05693766 Gene Signatures to Guide HR+MBC Therapy in a Diverse Cohort
NCT05868226 PRE-I-SPY Phase I/Ib Oncology Platform Program
NCT05047926 Prehabilitation for Stage IIIC-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients
NCT03452774 SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
NCT02207465 A Phase I Dual Dose Escalation Study of Radiation and Nab-Paclitaxel in Patients With Unresectable and Borderline Resectable Pancreatic Cancer
NCT05691465 Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells
NCT04329065 Concurrent WOKVAC Vaccination, Chemotherapy, and HER2-Targeted Monoclonal Antibody Therapy Before Surgery for the Treatment of Patients With Breast Cancer
NCT06833866 Phase I Trial of 5-Fluorouracil (5FU) -Based Therapy in Combination With Hydroxytyrosol (HT) in Patients With Advanced or Metastatic Colorectal Cancer
NCT06090266 A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents
NCT05327465 Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy
NCT06799065 First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer
NCT04812366 Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer
NCT06253520 Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer
NCT05458674 Tucatinib+Trastuzumab+Eribulin in HER2+ MBC
NCT05941520 Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer
NCT05485974 A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation
NCT04449874 A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation
NCT03090165 Ribociclib and Bicalutamide in AR+ TNBC
NCT04824027 Breast Elasticity Imaging During Neoadjuvant Chemotherapy
NCT04294927 TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention
NCT04796220 Focused Ultrasound and Gemcitabine in Breast Cancer
NCT06100874 A Single-arm Phase II Trial of SAcituzumab Govitecan and Trastuzumab for HER2+ Metastatic Breast Cancer After Trastuzumab dEruxtEcaN (SATEEN)
NCT05020574 Microbiome and Association With Implant Infections
NCT06217874 Collection of Specimens and Clinical Data for Patients With Recurrent or Metastatic Breast Cancer or Male Breast Cancer
NCT02918474 Decision Making Tool in Supporting Decision Making in Contralateral Prophylactic Mastectomy in Patients With Newly Diagnosed Breast Cancer
NCT05361174 A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer
NCT03538665 The DETECT Study: Discovery and Evaluation of Testing for Endometrial and Ovarian Cancer in Tampons
NCT06625320 Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)
NCT05111574 Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery
NCT05799274 Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer
NCT05679674 Stereotactic Body Radiation and Tumor Treating Fields for Locally Advanced Pancreas Cancer
NCT06068257 Tumor-Derived FGF19
NCT03972657 A Trial to Find Out if REGN5678 is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors
NCT05227326 AOH1996 for the Treatment of Refractory Solid Tumors
NCT04275557 Using Radiogenomics to Predict Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas
NCT05948826 First in Human Study of TORL-3-600 in Participants With Advanced Cancer
NCT07033026 An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.
NCT05563220 Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Patients With Metastatic Breast Cancer
NCT06146920 Use of Serial Plasma NGS as a New Efficacy Metric to Guide Immunotherapy Treatment Discontinuation
NCT06926920 A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer
NCT04998682 Prospective Evaluation of Targeted Axillary Dissection (TAD)
NCT06393374 Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
NCT05115474 Study of Screening Brain MRIs in Stage IV Breast Cancer
NCT05107674 A Study of NX-1607 in Adults With Advanced Malignancies
NCT06437574 Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer
NCT05958082 Utilization of Educational Interventions in Completion of Genetic Testing in Black Patients with High-Risk Prostate Cancer
NCT03995082 Breast Cancer Patient Engagement With Patient Reported Outcome Measure Survey
NCT06229392 A Study to Evaluate the Intratumoral Influenza Vaccine Administration in Patients With Breast Cancer
NCT06566092 Study of Autologous Tumor-Infiltrating Lymphocytes in Pediatric, Adolescent, and Young Adult Participants
NCT02478892 Preliminary Evaluation of Screening for Pancreatic Cancer in Patients with Inherited Genetic Risk
NCT04703244 Development of Patient Derived Xenografts (PDX) in Patients With Breast Cancer
NCT06614192 A Randomized Trial Assessing Adverse Events and Disease Activity When Comparing Intravenously (IV) Infused ABBV-400 to Trifluridine and Tipiracil (LONSURF) Oral Tablets Plus IV Infused Bevacizumab in Adult Participants With c-Met Over-Expressed Refractory Metastatic Colorectal Cancer
NCT05376592 Assoc. of Genomic Polymorphisms With Cancer Cachexia in Subjects With Panc Adenocarcinoma
NCT06562192 Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
NCT02402244 Project: Every Child for Younger Patients With Cancer
NCT05218044 Cryoablation as a Minimally Invasive Alternative to Surgery for Managing Ductal Carcinoma In Situ
NCT06083844 Phase II Investigation of Pembrolizumab in Combination With Bevacizumab and Oral Cyclophosphamide in Patients With High Grade Ovarian Cancer and Surgically Documented Minimal Residual Disease After Frontline Therapy
NCT04879940 Phase II Study to Evaluate the Safety and Efficacy of Prostatic Artery Embolization
NCT05795101 TRUDI: TDXD+Durva in HER2+/low IBC
NCT03228667 QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors
NCT06388967 Pancreatic Cancer Detection Consortium
NCT05684367 Exercise to ReGain Stamina and Energy (The EXERGISE Study)
NCT05691491 Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness
NCT06173362 Abiraterone and Prednisone or Darolutamide for the Treatment of Advanced Prostate Cancer
NCT06411691 KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer
NCT05272462 Oral Minoxidil for the Treatment of Recurrent Platinum Resistant Epithelial Ovarian Cancer
NCT06445062 Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
NCT04588662 A Prospective Natural History Study in Uveal Melanoma
NCT06568562 XL092 in Patients With Metastatic Castration-Resistant Prostate Cancer
NCT04282044 Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies
NCT02870244 Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes
NCT06315491 A Study of CBX 12 in Subjects With Platinum Resistant or Refractory Ovarian Cancer
NCT05959291 Discontinuation of Maintenance HER-2 Directed Therapy in Long-Term Survivors of Metastatic HER-2 Positive Breast Cancer
NCT06922591 Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients
NCT06646627 Clinical Trial of Autologous B7-H3 CAR T Cells in Reoccurent Platinum-resistant Ovarian Tumors
NCT06318273 A Study to Assess Adverse Events, and How Intravenously (IV) Infused ABBV-969 Moves Through the Bodies of Adult Participants With Metastatic Castration-Resistant Prostate Cancer
NCT05497531 Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers
NCT06402331 FPI-2265 (225Ac-PSMA-I&T) for Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC)
NCT04569773 Choosing Ovarian Preservation or Removal Before Surgery for Endometrial Cancer
NCT05912231 Ultrahypofractionation and Normal Tissue Toxicity
NCT06073431 An Observational Research Study to Uncover Subtypes of Cancer Cachexia
NCT06593431 Extending Outcomes for Pancreas Cancer Patients With Nominal Oligometastatic Disease (EXPAND): A Randomized Phase III Trial
NCT05123482 A Phase I/IIa Study of AZD8205 Given Alone or in Combination With Anticancer Drugs, in Participants With Advanced or Metastatic Solid Malignancies
NCT06141031 Phase I/IB Trial of Radiotherapy in Combination With TTI-101 in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma
NCT05797831 Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer
NCT05006131 Pancreatic Cancer Screening for At-risk Individuals
NCT03909282 Surgical Excision vs Neoadjuvant Radiotherapy+Delayed Surgical Excision of Ductal Carcinoma
NCT04808427 Pilot Study to Investigate Magnetic Resonance (MR) Image Guided Focal Therapy in Prostate Cancer
NCT05092373 Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax
NCT04175431 Prostate Specific Membrane Antigen (PSMA) or (FACBC) PET/CT Site-Directed Therapy for Treatment of Prostate Cancer, Flu-BLAST-PC Study
NCT05319873 Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer
NCT01638676 A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients
NCT06339827 ASk Questions in GYnecologic Oncology (ASQ-GYO)
NCT05546827 PRISAM: Pre-Operative Radiotherapy and Immunotherapy for Sinonasal and Anorectal Melanoma
NCT06294873 Stool Sample Collection Study
NCT03746431 A Phase 1/2 Study of [225Ac]-FPI-1434 Injection
NCT04471727 A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/HPN328-4001)
NCT06471673 A Study of BRIA-OTS Cellular Immunotherapy in Metastatic Recurrent Breast Cancer
NCT05611931 Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma
NCT05206331 CEM to Reduce Biopsy Rates for Less Than Highly Suspicious Breast Abnormalities: a Prospective Study
NCT05484973 Study to Assess the Ability of the Portable Scalp Cooling System (PSCS) to Prevent Hair Loss
NCT03562273 GammaPod Registry and Quality of Life Nomogram
NCT04573231 Evaluation of PSMA in HER2- AR+ Metastatic Breast Cancer
NCT05770531 Circulating Tumor DNA to Guide Changes in Standard of Care Chemotherapy
NCT05653882 A Study Evaluating AB248 Alone or in Combination with Pembrolizumab in Adult Patients with Solid Tumors
NCT05869682 Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy
NCT06671782 A Study of a Pelvic Floor Muscle Exercise Program Before and After Radical Prostatectomy
NCT07023731 A Study to Evaluate ARV-806 in Adults With Advanced Cancer That Has the KRAS G12D Mutation
NCT06270082 Study of IK-595 in RAS- or RAF-altered Advanced Tumors
NCT05746182 Genetic Predisposition Testing Program for Pancreatic Neuroendocrine Neoplasms
NCT04406831 The Role of MicroRNA in the Diagnosis, Prognosis and Response to Treatment in Pancreatic Cancer
NCT06545682 Phase Ib Study of AlpeliSib With PEmbroLizumab in Patients With mEtastatic Breast caNcer or melanomA (SELENA)
NCT06253494 Pembrolizumab, Lenvatinib and IL-15 Superagonist N-803 in Combination With HER2 Targeting Autologous Dendritic Cell (AdHER2DC) Vaccine in Participants With Advanced or Metastatic Endometrial Cancer
NCT05269160 Topical Dermaprazole for Radiation Dermatitis in Breast Cancer Patients (TOPAZ)
NCT05608694 MRI Screening in Men at High Risk of Developing Prostate Cancer
NCT05535894 Endoscopic Radiofrequency Ablation of Celiac Ganglion for Pain Management and Improvement of Quality of Life in Patients With Unresectable Pancreatic Cancer
NCT04134260 Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer, INNOVATE Trial
NCT06179160 A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
NCT03876860 An Enhanced Vaginal Dilator to Reduce Radiation-Induced Vaginal Stenosis
NCT05633160 64Cu-SAR-BBN and 67CU SAR-BBN for Identification and Treatment of Gastrin Releasing Peptide Receptor (GRPR)-Expressing Metastatic Castrate Resistant Prostate Cancer in Patients Who Are Ineligible for Therapy With 177Lu-PSMA-617 (COMBAT)
NCT04550494 Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations
NCT05304962 FIH Study of RGT-419B Alone and With Endocrine Therapy in HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancer
NCT03971591 Men Moving Forward: A Lifestyle Program for African-American Prostate Cancer Survivors
NCT02861573 Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)
NCT06450873 Turkey Tail Mushroom for Treating Post-Menopausal Women With HER2-Negative ER-Positive Breast Cancer Undergoing Surgery
NCT06727773 Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer
NCT06608927 Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma
NCT05812027 A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors
NCT05586360 T-reg Function Changes: a Novel Immune Regulatory Effect Underlying Benefit of Statin Use on Lethal Prostate Cancer
NCT06023576 A Study of Blood Pressure Control During Cancer Treatment
NCT04157127 Th-1 Dendritic Cell Immunotherapy Plus Standard Chemotherapy for Pancreatic Adenocarcinoma
NCT05477576 Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy
NCT05698576 TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer
NCT04967976 Breast Mesh Used in Two-staged Breast Reconstruction
NCT04701476 TATE and Pembrolizumab (MK3475) in mCRC and NSCLC
NCT05983276 Decitabine and Selinexor in Combination to Reverse Drug Resistance With Standard Chemotherapy in Ovarian Cancer
NCT06312176 A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
NCT06432660 Eye Plaque Brachytherapy for Ocular Melanoma
NCT05604560 A Neoadjuvant Study of Tislelizumab and SX-682 for Resectable Pancreas Cancer
NCT05408260 A Study to Compare the Effectiveness of Two Types of Ultrasound Technologies in Women Who Have Had Breast Cancer
NCT04147494 Experimental PET Imaging Scans Before Cancer Surgery to Study the Amount of PET Tracer Accumulated in Normal and Cancer Tissues
NCT03495427 PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men w/ High Decipher Test Scores
NCT05665660 Developing and Evaluating Culturally Relevant Interventions to Improve Breast Cancer Screening
NCT04666727 Role of Diet on the Microbiome of the Digestive System
NCT04815876 PReclude Infection EVEnts With No Prophylaxis Transperineal Biopsy 2
NCT06399276 4:3 Intermittent Fasting Intervention in Adults With Breast Cancer and Overweight or Obesity
NCT04697576 Intralesional Influenza Vaccine for the Treatment of Stage I-IV Melanoma
NCT04709276 A Study of Chemoimmunotherapy for the Treatment of Men With Neuroendocrine or Aggressive Variant Metastatic Prostate Cancer
NCT05721976 With Love, Grandma ("Con Cariño, Abuelita") Pilot Study
NCT06172127 PHESGO Maintenance After T-DXd Short Induction for HER2+ Unresectable Locally Recurrent or Metastatic Breast Cancer
NCT06594991 A Study of Fianlimab, Cemiplimab, and Ipilimumab in People With Melanoma
NCT06239194 Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
NCT05627960 First in Human Phase 1 Study of AG01 Anti-Progranulin/GP88 Antibody in Advanced Solid Tumor Malignancies
NCT05910294 A Study to Prevent and Improve Sexual Health Concerns for People With Breast Cancer
NCT04878094 A Study of Intra-operative Imaging in Women With Ovarian Cancer
NCT05417594 Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
NCT05076760 MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors
NCT02064673 Adjuvant Curcumin to Assess Recurrence Free Survival in Patients Who Have Had a Radical Prostatectomy
NCT06524973 Telehealth Self-Management Coaching Sessions to Improve Quality of Life in Pancreatic Cancer Survivors and Their Family Care Givers
NCT05856773 Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy
NCT05034627 Calaspargase Pegol-Mnkl and Cobimetinib for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer
NCT06620627 Prospective Collection of Samples to Enable the Development of Natera Screening Assay for Early Cancer Detection
NCT01530373 Solifenacin Compared to Clonidine for Reducing Hot Flashes Among Breast Cancer Patients
NCT04903873 A Study to Evaluate Safety, Efficacy, and Pharmacokinetics in Participants With Advanced Solid Tumors
NCT06081127 Breast Cancer Pre-habilitation and Prospective Surveillance to Prevent, Detect, and Optimize Physical and Function
NCT05556473 F-Tryptophan PET/CT in Human Cancers
NCT04787744 Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer
NCT04106492 Phase 1/2a Study of SQ3370 in Patients With Advanced Solid Tumors
NCT05086692 A Beta-only IL-2 ImmunoTherapY Study
NCT04609592 Study of PRRT in Metastatic, World Health Organization (WHO) Grade 1 or 2, SSTR Positive, GEP-NET Who Are Candidates for Cytoreductive Surgery
NCT06568692 A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer
NCT06478589 Patient Priorities for Survivorship Care in Older Breast Cancer Survivors
NCT03804944 Converting HR+ Breast Cancer Into an Individualized Vaccine
NCT04631744 Cabozantinib in Patients With Metastatic Castrate Resistant Prostate Cancer (mCRPC)
NCT06627244 Study of Tebentafusp and Radioembolization in the Treatment of Metastatic Uveal Melanoma
NCT05535192 TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients
NCT06157892 A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors
NCT06965192 Designing Visual Tools to Enhance Cancer Surgeon Decision-making
NCT06538389 High Cannabidiol Plant Extract (BRC-001) to Improve Aromatase Inhibitor-Induced Arthralgia in Women With Breast Cancer
NCT05912244 A Study of IO102/IO103, Nivolumab, and Relatlimab in People With Melanoma
NCT04512144 Mindfulness in Endometrial and Cervical Cancer
NCT06548789 Neoadjuvant Immune Checkpoint Blockade + a Prebiotic Food-enriched Dietary Intervention to Optimize Immune Response in Melanoma: NEO-PreFED
NCT05705492 Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer
NCT05498792 Study of CBL0137 in Combination With Ipilimumab and Nivolumab Therapy in Melanoma
NCT05537740 A First-in-human Study to Learn How Safe the Study Drug BAY3375968, an Anti-CCR8 Antibody, is, When Given Alone or in Combination With Pembrolizumab, How it Affects the Body, How it Moves Into, Through, and Out of the Body, and to Find the Best Dose in Participants With Advanced Solid Tumors
NCT05242744 FTT PET/CT in Metastatic Prostate Cancer
NCT06865768 An Investigational Scan (18F-rhPSMA-7.3 PET-mpMRI) for Targeted Prostate Biopsy Using TRUS-MR Fusion Technique
NCT06027268 Phase II Trial of Trilaciclib, Pembrolizumab, Gemcitabine and Carboplatin in Metastatic Triple-Negative Breast Cancer
NCT06728072 Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer
NCT05649072 Identifying Underserved Individuals inTexas With Hereditary Cancer Risk Using Mobile Mammography Units and Telegenetics.
NCT05352672 Clinical Study of Fianlimab in Combination With Cemiplimab Versus Pembrolizumab in Adolescent and Adult Patients With Previously Untreated Unresectable Locally Advanced or Metastatic Melanoma
NCT04668872 Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation
NCT02332668 A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)
NCT06182072 ProAgio in Pancreatic Ductal Adenocarcinoma (PDAC)
NCT06663072 Study to Test the Combination of Fulvestrant With Lu-DOTATATE for Advanced Pancreatic Neuroendocrine Tumors
NCT06696768 Clinical Trial of an Anti-cancer Drug, CA-4948 (Emavusertib), in Combination With Chemotherapy Treatment (FOLFOX Plus Bevacizumab) in Metastatic Colorectal Cancer
NCT04891068 BRE-04: Window of Opportunity Trial of Preoperative Low Dose Azacitidine in High-Risk Early Stage Breast Cancer
NCT01950572 Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma
NCT04657068 A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
NCT05415072 A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas
NCT06347068 Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells
NCT06465368 A Study to Learn About the Study Medicine PF-07220060 Together With Letrozole Compared to Letrozole Alone in Women Post Menopause
NCT06789172 A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors
NCT05132504 Neoadjuvant Folfirinox Combined With Pembrolizumab Followed by Surgery for Patients With Resectable Pancreatic Cancer
NCT06952504 A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
NCT05490472 JAB-2485 Activity in Adult Patients With Advanced Solid Tumors
NCT05094804 A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents
NCT05691504 Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial Cancers
NCT06877572 Weight Loss Management in Endometrial Cancer Survivors
NCT03270072 The Differential Impact of Proton Beam Irradiation Versus Conventional Radiation on Organs-at-risk in Stage II-III Breast Cancer Patients
NCT02863172 Molecular Basis for Variations in Hereditary Colorectal Cancer Syndromes
NCT05452681 Piloting Y-AMBIENT: A Quality of Life Intervention for Young African American Breast Cancer Survivors
NCT04589468 Researching the Effect of Exercise on Cancer
NCT05498272 Study of Neoadjuvant PARP Inhibition Followed by Radical Prostatectomy in Patients With Unfavorable Intermediate-Risk or High-Risk Prostate Cancer With Select HRR Gene Alterations
NCT07047872 A 3D-Printed External Breast Prosthesis for the Improvement of Patient-reported Outcomes Among Breast Cancer Patients That Underwent a Mastectomy Without Reconstruction
NCT06817668 Evaluating Tolerability of ePUHRT With Brachytherapy Boost
NCT05868668 Efficacy of Low-intensity Shockwave vs Radial Wave for Treatment of Erectile Dysfunction and Pelvic Pain
NCT04739072 Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study
NCT06001268 Support Through Remote Observation and Nutrition Guidance Program (STRONG-PCS)
NCT06408168 Phase II Study of REPotrectinib With or Without Fulvestrant in Patients With Hormone Receptor-positive Human Epidermal Growth Factor 2-negative Metastatic Invasive LObular Carcinoma Who Received a Prior Endocrine Therapy in Combination With Cyclin-dependent Kinase 4 and 6 Inhibitor (REPLOT Trial)
NCT05396872 Patient Decision-making About Precision Oncology in Veterans With Advanced Prostate Cancer
NCT05838768 Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.
NCT06915168 CIPN Decision Aid for the Improvement of Chemotherapy Decision Making in Patients With Breast Cancer
NCT05892068 A Study of Tucatinib Given Before Surgery to People With HER2+ Cancers That Have Spread to the Brain
NCT02526368 Pilot Study of (MR) Imaging with Pyruvate (13C) to Detect High Grade Prostate Cancer
NCT01102569 Pancreatic Cancer Genetics
NCT05554367 Palbociclib and Binimetinib in RAS-Mutant Cancers, A ComboMATCH Treatment Trial
NCT05355701 A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.
NCT04580667 Prospective Observational Exploratory Clinical Study to Determine the Assay Cut-Off for the RadTox Test in Prostate Cancer Patients to Predict Gastrointestinal Radiation Toxicity Using Circulating Cell Free DNA Directly From Plasma
NCT05736367 Investigating the Metabolic Pathways in Hormone Receptor Positive/HER2 Negative Breast Cancer
NCT04994067 Intra-Operative Radiation Registry
NCT03606967 Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer
NCT05130801 A Study of Multiparametric MRI and pHLIP® ICG in Breast Cancer Imaging During Surgery
NCT05046301 Contrast-Enhanced Mammography for the Evaluation of Mammographic Microcalcifications
NCT02772367 Generation of Heart Muscle Cells From Blood or Skin Cells of Breast Cancer Patients
NCT05464667 Preoperative Irradiation for Stage I Breast Cancer
NCT06666192 The Ohio State University (OSU) SCREEN Community Program
NCT02584244 Feasibility of the LUM Imaging System for Detection of Gastrointestinal Cancers
NCT03671044 A Study to Evaluate the Efficacy and Safety of Nanosomal Docetaxel Lipid Suspension in Triple Negative Breast Cancer Patients
NCT03823144 Intravital Microscopy in Human Solid Tumors
NCT03919292 Neratinib + Valproate in Advanced Solid Tumors, w/Expansion Cohort in Ras-Mutated Ca
NCT05472792 Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy
NCT05819892 Phase I Trial Testing the Safety and Tolerability of Chemoradiation Followed by Chemotherapy + Dostarlimab for Stage IIIC, Node Positive, Endometrial Cancer
NCT04722692 Delayed Sentinel Lymph Node Biopsy in Ductal Cancer in Situ
NCT06849544 Phase II Trial to Investigate the Safety and Efficacy of Four Dosing Regimens of OTL78 Injection
NCT04731844 Curcumin and Piperine in Patients on Surveillance for Monoclonal Gammopathy, Smoldering Myeloma or Prostate Cancer
NCT05726292 A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer
NCT05458544 [Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application
NCT06400472 A Study of LY4170156 in Participants With Selected Advanced Solid Tumors
NCT04854304 Abbreviate or FAST Breast MRI for Supplemental Breast Cancer Screening for Black Women at Average Risk and Dense Breasts
NCT06086704 Study of 18F-FFNP Breast PET/MRI
NCT01050504 Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer
NCT02279004 A Prospective Study of Plasma Genotyping as a Noninvasive Biomarker for Genotype-directed Cancer Care
NCT05501704 ETHAN - ET for Male BC
NCT06745804 Study of 68Ga-R10602
NCT06545604 Comprehensive Yoga Therapy Based Lifestyle Prehabilitation Program for Women With Ovarian Cancer
NCT06418204 Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
NCT06244004 FDG-PET-Guided Metastasis Directed Radiation Therapy for the Treatment of Metastatic Hormone Sensitive Prostate Cancer, The PRTY Trial
NCT04868604 64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE)
NCT05727904 Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.
NCT04265872 Bortezomib Followed by Pembrolizumab and Cisplatin in metTNBC
NCT06605404 Pan-tumor MRD Study
NCT06067269 Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients with Prostate Cancer, HEATWAVE Trial
NCT04365569 Evaluating the Effectiveness of an Individualized Nutrition and Physical Activity Counseling Program
NCT05703269 Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy
NCT06042569 Dose-Reduced Docetaxel With Cyclophosphamide for the Treatment of Vulnerable Older Women With Stage I-III HER2 Negative Breast Cancer, the DOROTHY Trial
NCT05334069 Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
NCT06444269 Precision Medicine in Action: Phase II Trial of Response Adaptive Ablative Pre-operative SPBI (RAPS) and Non-operative Sentinel Lymph Node Biopsy in Patients With Early-stage ER+ Breast Cancer: RAPS Trial
NCT04167969 The Use of Nanoparticles to Guide the Surgical Treatment of Prostate Cancer
NCT06907446 Comparison of New SUREcore Biopsy of Needle to Standard of Care During Transperineal Prostate Biopsies
NCT06698146 Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection
NCT03050268 Familial Investigations of Childhood Cancer Predisposition
NCT06835569 A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations
NCT05929768 Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
NCT06171269 Using MRI to Identify Areas to Receive Lower Doses of Radiation Treatment in Men With Prostate Cancerdose Mapping to Preserve Quality of Life
NCT04644068 Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies
NCT02977468 Effects of MK-3475 (Pembrolizumab) on the Breast Tumor Microenvironment in Triple Negative Breast Cancer
NCT05797168 Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors
NCT06844669 HER2HEART-US: Prevention of Cardiotoxicity in Breast Cancer Patients Receiving HER2-directed Therapy
NCT04611568 War on Melanoma™ Public Health & Education Campaign
NCT06371768 Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors
NCT05789069 A Study of HFB200603 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors
NCT05546268 Study of Oral MRT-2359 in Selected Cancer Patients
NCT03460769 Evaluation of a Mixed Meal Test for Diagnosis and Characterization and Type 3c Diabetes Mellitus Secondary to Pancreatic Cancer and Chronic Pancreatitis (DETECT)
NCT06103669 Locally AblatiVe TherApy in OLigO-pRogressive SOlid TUmorS (VALOROUS)
NCT06246968 A Study of Pembrolizumab and Cryoablation in People With Breast Cancer
NCT05712668 Telemedicine Use in Preoperative Counseling for Endometrial Cancer Survivors
NCT05113368 Regorafenib Combined With Fulvestrant in Recurrent Low-Grade Serous Ovarian Cancer
NCT03611868 A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors
NCT06228768 Acupressure for Aromatase Inhibitor-Associated Musculoskeletal Symptoms in Patients With Breast Cancer
NCT05751668 Finding an Effective Dose of GM1 to Reduce or Prevent Neuropathy (Numbness or Weakness) Due to Treatment With Paclitaxel (Phase II)
NCT06215469 Portable Scalp Cooling System (PSCS) to Prevent Hair Loss for Breast Cancer Patients (Cooler Heads)
NCT05318469 Ivermectin and Balstilimab for the Treatment of Metastatic Triple Negative Breast Cancer
NCT04349501 Biomarker Monitoring of Prostate Cancer Patients With RSI MRI (ProsRSI)
NCT06697301 Safety and Efficacy of EIK1001-006 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.
NCT06346067 A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)
NCT05417867 Evaluating the Association Between Changes in the Gut Microbiome, Fatigue, and Chemotherapy-Induced Nausea in Early Stage Breast Cancer
NCT04457596 T-DM1 and Tucatinib Compared with T-DM1 Alone in Preventing Relapses in People with High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial
NCT05232916 Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
NCT05590624 Metabolic Impact of Prospective Controlled Mediterranean Type Diets on Prostate Cancer
NCT05989724 A First-in-Human Study of SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors
NCT06205316 SBRT Versus Hypofractionated Radiotherapy for Biochemically Recurrent or Oligometastatic Prostate Adenocarcinoma
NCT04794816 What Women Want: Real Time Results During Screening Mammography in the Era of Patient-Experience Driven Care
NCT06584396 Evaluating Mechanical Properties of Post-Mastectomy Skin Flaps to Estimate Reconstruction Risks, the EMPOWER Study
NCT03819296 Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer
NCT06898996 FITting Non-invasive Tests in Lynch Syndrome Surveillance
NCT05646316 Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer
NCT05914116 A Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors
NCT04677816 Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients
NCT05013216 Mutant KRAS -Targeted Long Peptide Vaccine for Patients at High Risk of Developing Pancreatic Cancer
NCT04568616 Phase II Study of Neoadjuvant ArOMatase Inhibitor Therapy for ER+ Breast Cancer (NAOMI)
NCT05125016 A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With Cemiplimab or REGN5678 for Adult Participants With Advanced Prostate Cancer
NCT02960022 A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study
NCT05400122 Natural Killer (NK) Cells in Combination with Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer
NCT06084416 A Study of Sovilnesib in Subjects with Ovarian Cancer
NCT06566716 A Diagnostic Test to Evaluate Cancer Risk Before Surgery in Women with an Ovarian Mass
NCT06551116 QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer
NCT04022616 Myeloid-Derived Suppressor Cell Function in Breast Cancer Patients
NCT06364696 A Study to Find a Suitable Dose of ASP4396 in Adults With Solid Tumors
NCT06326216 Determination of Baseline Levels for Prostate Cancer-Derived Extracellular Vesicles Following Local Treatment of Prostate Cancer
NCT05716516 STUDY02001740;22SCH740: Estradiol For ER+ Advanced Breast Cancer (ESTHER)
NCT06307548 Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer
NCT06710548 REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors
NCT06202820 CV CARE: CardioVascular Care in PC Patients
NCT05929820 Impact of Protect Your Colon™ on CRC Screening
NCT06188520 A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors
NCT04545957 Jump: MR Simulation For Radiation Therapy Master Protocol
NCT06557148 A Study Comparing Cancer Imaging Approaches in People With Lobular Breast Cancer
NCT01042548 Proteomics and Radiomics Research of Breast Cancer Markers in Tissue, Interstitial Fluid and Serum
NCT06399757 A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors
NCT06026657 Gemcitabine and Ex Vivo Expanded Allogenic Universal Donor, TGFβi Natural Killer (NK) Cells With or Without Naxitamab (Danyelza) for the Treatment of Patients With Metastatic, GD2 Expressing, HER2 Negative Breast Cancer
NCT06743126 SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma
NCT06542757 Evaluation of Tumor Control Based on Serial Multiparametric MRI and Post-Treatment Biopsies For Patients Treated With Dose Intensification to the Dominant Intra-Prostatic Lesion (DIL) Using Ultra-Hypofractionated, MR-Guided Radiotherapy
NCT06557057 Impact of Aromatase Inhibitor Therapy on Glucose Homeostasis and Diabetes Risk
NCT04523857 ABemacicliB or Abemaciclib and HydroxYchloroquine to Target Minimal Residual Disease in Breast Cancer
NCT04616248 In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors
NCT05721248 STOP-HER2: Stopping Trastuzumab in HER2+ MBC
NCT05948657 Evaluation of Prostate Specific Membrane Antigen Positron Emission Tomography-Computed Tomography in Active Surveillance for Prostate CancEr
NCT06878248 A Study to Assess CLBR001+ABBV-461 in Subjects With Locally Advanced or Metastatic Breast Cancer
NCT06249048 Phase 1/2 Study of Intratumoral Injection of STX-001 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab
NCT06059963 A Prospective, Multi-center, Observational Study for Signal-C Test Evaluation
NCT05918263 Exercise for Tumor Suppressive Impact in Black Men With Prostate Cancer on Active Surveillance: The REMOVE Trial
NCT03987386 Conventional or Hypofractionated Radiation Therapy in Treating Patients With Prostate Cancer
NCT06100263 Breast Cancer Resiliency Through Exercise Program (B-REP)
NCT04158635 Gemcitabine, Nab-Paclitaxel, and Bosentan for the Treatment of Unresectable Pancreatic Cancer
NCT04789486 Nano-SMART: Nanoparticles With MR Guided SBRT in Centrally Located Lung Tumors and Pancreatic Cancer
NCT02896335 Palbociclib and Pembrolizumab In Central Nervous System Metastases
NCT04799535 Quantitative Microvasculature Imaging for Breast Cancer Detection and Monitoring
NCT03526835 A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
NCT06756035 CT-95 in Advanced Cancers Associated With Mesothelin Expression
NCT05496686 Targeted Alpha Particle Radiotherapy for Metastatic Uveal Melanoma
NCT03420963 Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors
NCT03620786 HIFU for Focal Ablation of Prostate Tissue: An Observational Study
NCT06778863 A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
NCT04115163 Biologically Optimized Infusion Schedule of Gemcitabine and Nab-Paclitaxel for the Treatment of Metastatic Pancreatic Cancer
NCT06595160 Association of Plant-based Diet and Gut Microbiome Signature with Response to Neoadjuvant Therapy in Pancreatic Ductal Adenocarcinoma
NCT06780176 A Study of Breast Cancer Risk Factors and Outcomes of People in Florida
NCT05467891 Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer
NCT05766891 Opioid-Sparing Effects of Nurse-Delivered Hypnosis During Breast Cancer Surgery
NCT05422794 Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer
NCT06750094 A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
NCT05040360 Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors
NCT06731894 Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors
NCT05969860 At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
NCT05000294 Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types
NCT04104776 A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
NCT05478694 Outcomes of Focal Ablation for Prostate Cancer
NCT05020860 Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer
NCT04234386 GammaPod Dose Escalation Radiation for Early Stage Breast Cancer
NCT06915025 Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant Chemotherapy in Newly Diagnosed Patients w/ Advanced EOC, Fallopian Tube or Primary Peritoneal Cancer
NCT06449222 Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast Cancer, When Given in Combination With Chemotherapy
NCT06171139 Tumor Genomic Pre-test Counseling Tool for Black or African-American Men With Prostate Cancer
NCT06666439 Longitudinal Tumor Burden Quantification Using Circulating Tumor DNA in Metastatic Lobular Breast Cancer
NCT06236139 Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer
NCT06774963 A Phase 1 Study of LNCB74 in Advanced Solid Tumors
NCT04871139 An Imaging Technology, Contrast-Enhanced Mammography, in Predicting Breast Cancer
NCT05900986 LS301-IT in Partial Mastectomy and Sentinel Lymph Node Biopsy (SLNB) for DCIS or Stage I-II Primary Invasive Breast Cancer
NCT06389786 Accuracy of 18F-rhPSMA-7.3 PET/ MRI for Prediction of Lymph Node Metastasis in Localized High-Risk Prostate Cancer
NCT05336786 Prostate Cancer Diagnosis by Multiparametric Ultrasound (Wholemount)
NCT06158139 Autologous CAR-T Cells Targeting B7-H3 in PDAC
NCT02189486 Prostate Cancer Upgrading Reference Set
NCT06037863 Evaluation of the Impact of Empty Versus Full Bladder in Patients with Prostate Cancer, RELIEF Trial
NCT04706663 Precision-Based Genomics in Prostate Cancer
NCT06300463 Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases
NCT06115486 EXERT-BCH Exercise Regimen to Improve Muscle Mass After Treatment of Breast Cancer
NCT04792463 Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome
NCT04751435 Developing New Educational Materials About Genetic Testing for a Diverse Group of Cancer Patients
NCT05840263 Couple-Based Mindfulness Intervention for Metastatic Colorectal Cancer
NCT06691035 Immunologic Targeting of ESR1 Receptor for Hormone Receptor Expressing Metastatic Breast Cancer
NCT06421935 M9466 Alone or in Combination in Advanced Solid Tumors (DDriver 501)
NCT06162663 Double-blind Randomized Controlled Trial Comparing Suvorexant 20 mg to Placebo for Treatment of Insomnia in Cancer Survivors
NCT04188535 Serial MRI Scans During Radiation Therapy
NCT03439735 Determinants of Resistance to Endocrine Therapy and a Cyclin-dependent Kinases 4 and 6 (CDK4/6) Inhibitor for HR+ MBC
NCT04887935 Neoadjuvant SGLT2 Inhibition in High-Risk Localized Prostate Cancer
NCT06617858 Trial of AMB-05X for Patients With ctDNA(+) Colorectal Cancer After Curative-intent Treatment
NCT05428735 The DRAGON 2 Trial
NCT03454035 Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors
NCT03382158 International PPB/DICER1 Registry
NCT06250335 Impact of a Prebiotic Food-enriched Diet (PreFED) in Combination With Ipilimumab/Nivolumab Combination Immune Checkpoint Blockade (ICB) in ICB-refractory Melanoma Patients
NCT05998135 Repurposing Atovaquone for the Treatment of Platinum-Resistant Ovarian Cancer
NCT04074135 Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors
NCT05524935 Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma
NCT05628363 Adaptive Stereotactic Body Radiation Therapy to the Prostate and Pelvic Nodes With Simultaneous Integrated Boost to the MR-detected Nodule for Patients With High-risk and Unfavorable Intermediate-risk Prostate Cancer
NCT05438563 MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Intermediate Grade Prostate Cancer
NCT06623396 A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer
NCT05054296 Modifying Metabolic Syndrome and Cardiovascular Risk for Prostate Cancer Patients on ADT Using a Risk Factor Modification Program and Continuous Fitbit Monitoring
NCT04130516 Study Assessing MTD, Safety, Tolerability, PK and Anti-tumor Effects of LNS8801alone and with Pembrolizumab
NCT06492616 A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
NCT04575935 Minimally Invasive Surgery After Neoadjuvant Chemotherapy for the Treatment of Stage IIIC-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer, LANCE Trial
NCT05384496 Axitinib and Nivolumab for the Treatment of Mucosal Melanoma
NCT05462496 Modulation of the Gut Microbiome With Pembrolizumab Following Chemotherapy in Resectable Pancreatic Cancer
NCT05930496 Evaluating the Effects of an Exercise Intervention on the Gut Microbiota in Stage II-III Colorectal Cancer Survivors
NCT03990896 Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial
NCT05548296 A Study of ACR-368 in Ovarian Carcinoma, Endometrial Adenocarcinoma, and Urothelial Carcinoma
NCT06428396 Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)
NCT05136196 BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study
NCT05377996 A Study of XMT-1660 in Participants With Solid Tumors
NCT05036096 Cone Beam Breast CT for Breast Cancer Screening
NCT04251416 A Study of Sacituzumab Govitecan (IMMU-132) in Endometrial Carcinoma
NCT05652686 A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)
NCT04847063 Individualized Response Assessment to Heated Intraperitoneal Chemotherapy (HIPEC) for the Treatment of Peritoneal Carcinomatosis From Ovarian, Colorectal, Appendiceal, or Peritoneal Mesothelioma Histologies
NCT06423963 Remote Exercise and Nutritional Prehabilitation for Pancreatic Cancer
NCT05226663 A Radiotracer ([18F]FluorThanatrace) by PET/CT for the Imaging of Breast Cancer
NCT06662435 GYNecologic Cancer-Related COGnitive Impairment
NCT04485286 Evaluation of PET Probe [68Ga]CBP8 in the Detection of Radiation Induced Tissue Injury
NCT06400563 MRg-NIRS Imaging System Breast Cancer Trial
NCT04914663 All-extremity Exercise During Breast Cancer Chemotherapy
NCT06193486 Autologous Gamma Delta T Cells to Target Prostate Stem Cell Antigen in mCRPC
NCT06014086 Intratumoral PH-762 for Cutaneous Carcinoma
NCT06820463 A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer
NCT04862663 Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)
NCT05225363 Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian Cancer
NCT05832086 Intermittent Fasting Using a Fasting-Mimicking Diet to Improve Prostate Cancer Control and Metabolic Outcomes
NCT06287463 Study of DCC-3084 in Participants With Advanced Malignancies Driven by the Mitogen-Activated Protein Kinase (MAPK) Pathway
NCT06788886 Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases
NCT04797039 MRI-Guided Cryoablation for Focal Native Prostate Cancer
NCT06294886 Vaginal Fluid Collection for Detection of Endometrial Cancer
NCT04721886 Contrast-Enhanced Ultrasound Scan for the Estimation of Tissue Pressure in Patients With Breast Cancer
NCT06342986 Intraperitoneal FT536 in Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer
NCT02476786 Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score
NCT03880422 Nutrition and Exercise Interventions in Reducing Androgen Deprivation Therapy-Induced Obese Frailty in Prostate Cancer Survivors
NCT06479239 Study of EGFRBi Armed Fresh PBMC in Metastatic or Unresectable Pancreatic Cancer
NCT06610539 PAS 1ml Magtrace® for Sentinel Lymph Node Biopsy in Breast Cancer Patients
NCT06353386 Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)
NCT05174286 Community Health Workers United to Reduce Colorectal Cancer and Cardiovascular Disease Among People at Higher Risk
NCT06662786 A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
NCT06044025 A Feasibility Study Evaluating a Role for Maintenance Therapy in Patients With Biochemically Progressive Castration Sensitive Prostate Cancer on Intermittent Androgen Deprivation Therapy
NCT06384222 Hyperpolarized (HP) 13C Pyruvate Magnetic Resonance Imaging (MRI) for Response Monitoring to Neoadjuvant Abiraterone
NCT05553522 Tucatinib, Trastuzumab, and Capecitabine With SRS for Brain Metastases From HER-2 Positive Breast Cancer
NCT06626022 Screening for Prostate Cancer Using High Resolution Micro-ultrasound Versus Multiparametric Magnetic Resonance Imaging.
NCT04430725 Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study
NCT05412225 A Study of an Alternative Treatment Approach (Preoperative Radiotherapy, Then Mastectomy, Then Immediate Reconstruction Surgery) in People With T4 Breast Cancer
NCT06262139 Evaluation of a Targeted Magnetic Resonance Imaging Contrast Agent in Prostate Cancer Patients
NCT03546686 Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women with Triple-negative Breast Cancer
NCT03677739 Young Melanoma Family Facebook Intervention or Healthy Lifestyle Facebook Intervention in Improving Skin Examination in Participants With Melanoma and Their Families
NCT04918186 Immunotherapy Platform Study in Platinum Resistant High Grade Serous Ovarian Cancer
NCT06246786 Breast/Cyclosporin A/TNBC (Triple Negative Breast Cancer)
NCT06870539 Feasibility of Saliva and Remote Monitoring of Active Cytomegalovirus (CMV) Infection and Symptoms During Ovarian Cancer Treatment
NCT06055439 A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy
NCT04511039 Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer
NCT02610439 Whole Exome Sequencing in Finding Causative Variants in Germline DNA Samples From Patients With Peripheral Neuropathy Receiving Paclitaxel for Breast Cancer
NCT05501886 Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer (VIKTORIA-1)
NCT06824064 Evaluation of RBS2418 in Patients with Advanced, Metastatic, and Progressive Colorectal Cancer
NCT05647564 PET/CT Characterization of Treatment Resistance
NCT05949021 OCTANE: Adjuvant Liposomal Doxorubicin and Carboplatin for Early-stage Triple-negative Breast Cancer
NCT06943521 A Study of MT-4561 in Patients With Various Advanced Solid Tumors
NCT06105684 Phase II Single Arm Trial of Low Dose Capecitabine in Patients With Advanced Breast Cancer
NCT06888102 A Platform Study of Epigenetic Therapy Before Prostatectomy in Men With Prostate Cancer
NCT06102902 Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer
NCT04363164 Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression
NCT05200364 A Study of STRO-002, an Anti-Folate Receptor Alpha Antibody Drug Conjugate, in Combination With Bevacizumab in Epithelial Ovarian Cancer
NCT06257264 A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors
NCT05826964 Levels of Circulating Tumor DNA as a Predictive Marker for Early Switch in Treatment for Patients With Metastatic (Stage IV) Breast Cancer
NCT06631521 Neoadjuvant Darolutamide and Relugolix Combination Preceding Radical Prostatectomy for Prostate Cancer
NCT05650021 Rectal Spacer for Prostate Cancer Radiation Image Guidance
NCT05786664 Breast Cancer Survivorship Biorepository
NCT06353321 Non-significant Risk (NSR) Study of [68Ga]-PSMA-11 (Illuccix) as a BgRT BioGuide on RefleXion X1
NCT06661902 Buffered Lidocaine for Reducing Pain in Patients Undergoing Prostate Biopsy, BURN Trial
NCT05743621 Study of TVB-2640 in Men With Metastatic Castration-Resistant Prostate Cancer
NCT05984602 A Phase IB Study to Determine the Safety and Tolerability of Canakinumab and Tislelizumab in Combination With Nab-Paclitaxel and Gemcitabine in the Neo-adjuvant Treatment of Patients With Pancreatic Cancer
NCT00923221 Collection of Blood From Patients With Prostate Cancer
NCT05413421 Study of ORIC-944 in Patients with Metastatic Prostate Cancer
NCT01174121 Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer
NCT05559164 Statins for Reduction of Cardiac Toxicity in Patients Receiving HER2 Targeted
NCT06085664 A Pilot Presurgical Trial of REGN5678 (Anti-PSMA x CD28) in Patients With High-risk, Localized Prostate Cancer Followed by Radical Prostatectomy
NCT02621021 A Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab
NCT06144164 A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer
NCT06401421 EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)
NCT05689021 CJNJ-67652000 and Prednisone for Treatment of Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations
NCT06888921 A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer
NCT05741164 Propranolol and Pembrolizumab for Tumor Re-sensitization and Treatment of Patients With Checkpoint Inhibitor Refractory Metastatic or Unresectable Triple Negative Breast Cancer
NCT05935384 SIBYL: obServation of Therapy Response With lIquid BiopsY evaLuation
NCT05685602 CA-4948 Added to Standard Chemotherapy to Treat Metastatic or Unresectable Pancreatic Cancer
NCT06428721 The Preventive Role of Fractionated Laser Resurfacing Against Actinic Neoplasia in an At-Risk Geriatric Population
NCT06580002 Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
NCT06036121 A Study of ADRX-0706 in Select Advanced Solid Tumors
NCT06535802 iCCaRE Consortium Pilot Project 1: Feasibility of a Point of Prostate Cancer Diagnosis Intervention for Newly Diagnosed Black Men
NCT06706921 18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy in Patients With Prostate Cancer
NCT06336902 Botensilimab Plus Balstilimab and Fasting Mimicking Diet Plus Vitamin C for Patients with KRAS-Mutant Metastatic Colorectal Cancer
NCT04857502 99mTc-PSMA-I&S Biodistribution in Patients With Prostate Cancer
NCT05926102 The Prostate Cancer, Genetic Risk, and Equitable Screening Study (ProGRESS)
NCT04368702 CONFIRM: Magnetic Resonance Guided Radiation Therapy
NCT04420702 Diffusion Basis Spectrum Imaging of the Prostate
NCT06873802 ZTE MRI Pulse Sequence Use for Visualization of Bone Cement, Breast Biopsy Markers
NCT06323421 Targeting Chronic Stress for Reducing Risk Factors for Colorectal Cancer
NCT04897321 B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)
NCT03833921 Evaluation of Response to Abiraterone/Prednisone by Race/Ethnicity and Other Factors in Metastatic Hormone Naive Prostate Cancer
NCT06397703 ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer
NCT05126290 CTNNA1 Familial Expansion Study
NCT06101290 Locally Ablative TherapY in Oligo-ProgressiVe GEnitourinary TumoRs (LAYOVER)
NCT06327490 A Study Evaluating the Feasibility and Compliance of Manual Lymphatic Drainage Comparing Indocyanine-Green (ICG) Guided vs. Traditional Guided in Patients Undergoing Axillary Node Dissection for the Treatment of Breast Cancer
NCT05968690 Naltrexone and Propranolol Combined With Immunotherapy
NCT06409390 Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer
NCT06067503 Biomarkers to Detect Endocrine Therapy Resistance
NCT04766190 DISCO: A Patient Intervention to Reduce the Financial Burden of Cancer
NCT06187103 Evaluation of Improved Onboard Patient Imaging
NCT04968964 Treatment Monitoring of Patients Receiving CDK 4/6 Inhibitors for Hormone Receptor (HR) Positive, HER2 Negative Metastatic Breast Cancer (MBC) With or Without the Addition of DiviTum® Serum Thymidine Kinase 1 (TK1) Activity Testing
NCT04019964 Nivolumab in Biochemically Recurrent dMMR Prostate Cancer
NCT04373564 Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years
NCT05780684 Individualized Dose Escalation of 5-FU for Gastrointestinal Cancer
NCT03054584 Genetic Basis of Melanocytic Nevi
NCT06833502 Phase II Study of Systemic Screening in Pathologic Node Positive Breast Cancer
NCT04139902 Neoadjuvant PD-1 Inhibitor Dostarlimab (TSR-042) Vs. Combination of Tim-3 Inhibitor Cobolimab (TSR-022) and PD-1 Inhibitor Dostarlimab (TSR-042) in Melanoma
NCT05398302 Image-Guided Biopsies to Identify Mechanisms of Resistance in Patients With Metastatic Castration Resistant Prostate Cancer Treated With 177Lu-PSMA Radioligand Therapy
NCT04990921 Study of Palliative Radiation Combined with Pembrolizumab in Unresectable Metastatic Stage IV Breast Cancer
NCT07020221 A Phase 1/2a Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
NCT06599502 A Phase I/IIa Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AZD0022 as Monotherapy and in Combination With Anti-cancer Agents in Adult Participants With Tumours Harbouring a KRASG12D Mutation
NCT05677802 Feasibility Study of Biobehavioral Stress Reduction Intervention in Patients With Triple Negative Breast Cancer
NCT06136884 A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors
NCT06917079 BBO-11818 in Adult Subjects With KRAS Mutant Cancer
NCT05050084 Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial
NCT05598879 Global Cardio Oncology Registry
NCT06439979 Rural Adult and Youth Sun Protection Study
NCT06047379 Safety and Efficacy of NEO212 in Patients with Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
NCT05755984 3D Printed Breast Models in the Surgical Management of Breast Cancer
NCT06650579 REVELUTION-2: Relugolix+Abiraterone Acetate (AA) Versus Leuprolide+AA Cardiac Trial
NCT04792684 Collection of Samples USOPTIVAL Study
NCT04753879 Multi-agent Low Dose Chemotherapy GAX-CI Followed by Olaparib and Pembro in Metastatic Pancreatic Ductal Cancer.
NCT05170802 Pancreatic Cancer & Surgical Resection
NCT04005690 Targeted Pathway Inhibition in Patients With Pancreatic Cancer
NCT05296421 Investigating Targetable Metabolic Pathways Sustaining Pancreatic Cancer
NCT06238921 Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain Metastases
NCT04759664 LUT014 for the Reduction of Dose-Limiting Acneiform Lesions Associated With EGFRI Treatment of mCRC
NCT05919264 FOG-001 in Locally Advanced or Metastatic Solid Tumors
NCT06103864 A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer
NCT06105021 Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor
NCT05950464 Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer
NCT06150664 A Phase 1 of CTX-8371 in Patients With Advanced Malignancies
NCT04521764 A Vaccine (MV-s-NAP) for the Treatment of Patients with Invasive Metastatic Breast Cancer
NCT05378464 Adoptive T Cell Therapy Following HER2-Pulsed Dendritic Cell Vaccine & Pepinemab /Trastuzumab in Patients w/ Metastatic HER2+ Breast Cancer
NCT06434064 Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With Metastatic or Inoperable, Locally Advanced Triple Negative Breast Cancer
NCT06655064 Registry to Evaluate Long-Term Outcomes in Patients Who Undergo 68-Ga-PSMA-11 PET/CT Imaging Evaluations
NCT05559879 Cabozantinib and Dostarlimab in Recurrent Gynecologic Carcinosarcoma
NCT04472338 Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study
NCT06185738 WeCanManage. An mHealth Self-management Tool
NCT04863443 Nonlinear Elasticity Mapping of Breast Masses
NCT04489238 Collection of Information to Better Understand Young Onset Colorectal Cancer
NCT05682443 ONC-392 Plus Lutetium Lu 177 Vipivotide Tetraxetan in Patients With mCRPC
NCT05505643 Cryoablation vs Lumpectomy in T1 Breast Cancers
NCT05239338 Preserving Fertility After Colorectal Cancer Study
NCT05069038 Clinical Trial Assessing the Safety of Neoadjuvant Palbociclib in Combination With Endocrine Therapy
NCT03384238 Panitumumab-IRDye800 in Patients With Pancreatic Cancer Undergoing Surgery
NCT05527184 First in Human Study of IMGN151 in Recurrent Gynaecological Cancers
NCT05134779 De-convoluting Interactions Between Genes, the Cancer Environment, and the Immune System to Develop Therapies That Work for You
NCT06127979 A Study of Changes in Ki67 Expression in People With Breast Cancer Receiving Endocrine Therapy Before Surgery
NCT06691984 Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Participants With Progressive Metastatic Castration-Resistant Prostate Cancer
NCT05507879 TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer
NCT05675579 A Phase II Study of Neoadjuvant Sacituzumab Govitecan and Pembrolizumab Therapy for Immunochemotherapy-resistant Early-stage Triple-negative Breast Cancer (TNBC)
NCT01042379 I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
NCT03941379 A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma
NCT06108479 Study of DF6215 in Patients with Advanced Solid Tumors
NCT06629779 A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
NCT04986579 Scalp Cooling in MBC
NCT06728579 Enhanced Pain Coping in Cancer (EPIC): A Study of Managing Treatment-Related Joint Pain in Breast Cancer Survivors
NCT06272864 BostonGene and Exigent Genomic INsight Study
NCT06783179 Postoperative Outcomes and Patient Satisfaction With Mayo Clinic Florida Care Hotel After Mastectomy and Tissue Expander Placement
NCT04820179 Atezolizumab + Cabozantinib in Patients w/ Metastatic, Refractory Pancreatic Cancer
NCT05683964 Androgen Receptor Signaling and Prostate-Specific Membrane Antigen Expression
NCT04469764 Abemaciclib for the Treatment of Recurrent Ovarian or Endometrial Cancer
NCT04913064 Effects of White Button Mushroom on Inflammation in Obese Postmenopausal Women at High Risk of Breast Cancer
NCT05423964 Impact of AI on Trainee ADR
NCT06330064 A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)
NCT04965064 Trial of Neratinib Plus Capecitabine in Subjects with HER2-Negative Metastatic Breast Cancer with Brain Metastases and Abnormally Active HER2 Signaling
NCT04698564 Utility of Hyperpolarized 13C-pyruvate Metabolic Magnetic Resonance Imaging
NCT06518564 Avelumab and M1774 in ARID1A-mutated Endometrial Cancer (Prior IO)
NCT01503190 The Immune System's Response to Young Women's Breast Cancer
NCT04003038 Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery
NCT06336538 Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors
NCT06284590 Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination with Pembrolizumab, in Unresectable Melanoma Patients
NCT04705038 Effect of Education on Treatment Decision Making for Patients With Prostate Cancer on Chronic Hormone Treatments
NCT05280314 Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors
NCT06484595 Clinical Trial Navigation to Increase Participation and Diversity in Cancer Clinical Trials
NCT06130995 Relugolix + Enzalutamide Study in High-Risk Prostate Cancer
NCT06315595 Improvements in Dynamic Contrast-Enhanced MR Angiography and Perfusion and Non-Contrast MRI
NCT05471414 Whole-Food Plant-Based Diet to Control Weight and MetaboInflammation in Overweight/Obese Men With Prostate Cancer
NCT05301114 Social Risk Factors and Discrimination in Cancer Survivorship
NCT05607095 A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, or Dedifferentiated Liposarcoma
NCT06055881 Primary Breast Oligoprogressive Sites Treated With Radiotherapy to Obviate the Need to Change Systemic Therapy
NCT04354064 Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors
NCT06451614 SpaceIT Hydrogel System for Perirectal Spacing
NCT04839614 Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia
NCT06051695 A Study to Evaluate the Safety and Efficacy of A2B694, a Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
NCT01851395 Rapid Autopsy and Procurement of Cancer Tissue
NCT06524895 Reiki Breast Surgery QOL Project for Women Undergoing Breast Surgery
NCT05933395 Genetically-informed Therapy for ER+ Breast Cancer Post-CDK4/6 Inhibitor
NCT05616650 Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate Tumor
NCT06400550 Identification of Metabolic Phenotypes Associated With Melanoma Metastasis
NCT04486755 Hypofractionated Accelerated Pelvic Nodal Radiotherapy (GCC 2048)
NCT04606914 Study of Carboplatin and Mirvetuximab Soravtansine in First-Line Treatment of Patients Receiving Neoadjuvant Chemotherapy with Advanced-Stage Ovarian, Fallopian Tube or Primary Peritoneal Cancer
NCT04379414 YES Study - Newly Diagnosed/Metastatic Intervention
NCT05974150 Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring
NCT06054555 A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Melanoma
NCT06961955 5 vs. 9-day Course of Whole Breast Radiotherapy With Boost for Early-stage Breast Cancer
NCT05573555 TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study B)
NCT06643455 Mindfulness Intervention for Improving Nutrition in the Digital Kitchen Among Stage I-III Breast Cancer Survivors, MIND Trial
NCT04775355 Study to Detect Changes in Urinary and Gut Microbiome During Androgen Deprivation Therapy and Radiation Therapy in Patients With Prostate Cancer
NCT06616155 Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer
NCT06112314 IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)
NCT06966050 Multi-center MRD Registry for Inflammatory Breast Cancer
NCT06730750 A Study of BMS-986490 With or Without Bevacizumab in Advanced Solid Tumors
NCT04585750 The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
NCT05130255 GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2
NCT06483555 Basal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxel
NCT05819255 TRAQinform Assessment of Immunotherapy Response
NCT05053555 High Dose-Rate Brachytherapy for the Treatment of Both Primary and Secondary Unresectable Liver Malignancies
NCT05715255 Adaptive Symptom Self-Management Immunotherapy Study
NCT03987555 Paclitaxel Therapeutic Drug Monitoring in Cancer Patients
NCT06411795 Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy
NCT00899301 Collecting and Storing Tissue Samples From Women With or Without Breast Cancer
NCT05039801 IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors
NCT06342401 Early Onset Colorectal Cancer Detection
NCT06512350 Identifying Patterns in the Breath of Individuals With Breast Cancer
NCT05086250 Feasibility Study of Oral Ketamine Versus Placebo for the Treatment of Anxiety in Patients With Pancreatic Cancer
NCT03424850 Safety and Efficacy of 21 Gy, 23 Gy and 25 Gy for High Dose Rate (HDR) Prostate Brachytherapy
NCT04765150 Integrating Quantitative MRI and Artificial Intelligence to Improve Prostate Cancer Classification
NCT03067181 Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
NCT06500481 Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial
NCT05806814 Sipuleucel-T Based Autologous Cellular Immunotherapy for Advanced Prostate Cancer
NCT01416714 Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Surgery or Biopsy
NCT06580314 Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
NCT05827614 Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), in Subjects With Tumors With Oncogene Amplifications
NCT05780814 The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer
NCT06792695 A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer
NCT03513614 Tailored Axillary Surgery With or Without Axillary Lymph Node Dissection Followed by Radiotherapy in Patients With Clinically Node-positive Breast Cancer (TAXIS)
NCT05014295 Patient Recall of Cancer Screening and Diagnosis
NCT06302595 MRI Guided Prostate Biopsy
NCT05863195 Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial
NCT07042581 A Study of Revaree Plus in People With Breast Cancer
NCT04687969 Multimodal Machine Learning Characterization of Solid Tumors
NCT06362369 A Study of Oral 7HP349 (Alintegimod) in Combination with Ipilimumab Followed by Nivolumab Monotherapy
NCT01365169 Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"
NCT05469269 Cleveland African American Prostate Cancer Project
NCT06099769 A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer
NCT05755269 Adding a Genetic Risk Evaluation to Standard Breast Cancer Risk Assessment for African American and Hispanic Women
NCT06500169 Golf Recreational Exercise for Enhanced Survivorship in Prostate Cancer Survivors
NCT06112990 Creatine Supplementation and Resistance Training to Preserve Muscle Mass and Attenuate Cancer Progression
NCT05128890 Evaluation of Resection Techniques for Pancreatic Tumors
NCT06562543 A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer
NCT04907643 Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes
NCT03842943 Neoadjuvant Combination Immunotherapy for Stage III Melanoma
NCT06686043 HPV Vaccine, Imiquimod, and Metformin Combination Trial
NCT05972343 COOL-IT-PRO: Cryoablation of Breast Cancer in Non-surgical Patients
NCT06263543 Sequencing Antibody Drug Conjugates in ER+/HER2 LOW MBC
NCT06528990 Telehealth Intervention for Ostomy Self-Management
NCT05074290 Pharmacokinetics and Safety of Epidiferphane and Taxanes in Breast Cancer Patients
NCT05223803 TERPS Trial for De Novo Oligometastic Prostate Cancer
NCT06441890 BRE-10: Biomarker Optimization of Neoadjuvant Therapy in Breast Cancer
NCT06218303 Prototype DAA/TAA Vaccine Targeting MUC1 for Immune Interception and Prevention in Ductal Carcinoma In Situ
NCT04658303 Evolution of Metabolic and Immune Dysfunction in In-transit Melanoma
NCT05429203 Comparison of Duodenoscope With Single-use Distal Cover and the Conventional Reusable Duodenoscope
NCT06738303 Cabazitaxel +/- Carboplatin vs 177Lu-PSMA-617 in Metastatic Castrate-resistant Prostate Cancer
NCT04477343 A Study to Evaluate the Safety and Tolerability of SX-682 in Combination With Nivolumab as a Maintenance Therapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma
NCT05911243 Feasibility of Auricular Acupressure for Appetite and Weight in Patients With Stage II-IV Gastric, Esophageal, and Pancreatic Cancer
NCT06956690 A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of ENV-501 in Patients With HER3-Expressing Solid Tumors
NCT05518903 Investigational Scan (68Ga-FAPI-46 PET/CT) for Imaging of Cancer-Associated Fibroblasts for Localized Pancreatic Ductal Adenocarcinoma
NCT02393703 Interrogation of Exosome-mediated Intercellular Signaling in Patients With Pancreatic Cancer
NCT06470243 Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body
NCT05030038 Oral Aromatase Inhibitors Modify the Gut Microbiome
NCT06200103 Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer
NCT02276443 Molecular Testing and Imaging in Improving Response in Patients With Stage I-III Triple-Negative Breast Cancer Receiving Chemotherapy MDACC Breast Moonshot Initiative
NCT03456843 Therapeutic Effect of Cytoreductive Radical Prostatectomy in Men With Newly Diagnosed Metastatic Prostate Cancer
NCT05049538 Determine the Utility of Liquid Biopsies and Tumor Molecular Profiling in Predicting Recurrence in Endometrial Cancers
NCT05592938 Partial Breast Re-irradiation Using Ultra Hypofractionation (PRESERVE)
NCT03449238 Pembrolizumab And Stereotactic Radiosurgery (Srs) Of Selected Brain Metastases In Breast Cancer Patients
NCT06184750 Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial
NCT05286814 PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma
NCT06461650 Preoperative Nicotine Cessation for Women With Breast Cancer Recommended for Reconstruction
NCT06049355 EMBRACE: Exercising Together
NCT04049214 Perioperative Mindfulness Proposal
NCT04624555 The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors
NCT05939414 An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.
NCT06392295 PSMA-Directed Para-Aortic Radiation Therapy for Oligorecurrent Prostate Cancer
NCT06409195 A Trial to Study the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Seborrheic Keratoses and Non-Melanoma Skin Cancers
NCT06617481 PET Scan Study to Detect Prostate Cancer in Patients with Early PSA Recurrence
NCT00005095 Specimen and Data Study for Ovarian Cancer Early Detection and Prevention
NCT06469281 A Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian Cancers
NCT05219695 Medical Imaging and Thermal Treatment for Breast Tumors Using Harmonic Motion Imaging (HMI)
NCT03137095 Effects of Chemotherapy on Cognitive Function in Breast Cancer Patients & Non-Cancer Control Subjects With Optional Sub-Study Research Brain MRI
NCT05435495 Mechanisms of Resistance to PSMA Radioligand Therapy
NCT06745895 Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening
NCT06673095 Narrow Excision Versus Wide Excision for the Treatment of Adults With Invasive Cutaneous Melanoma, ICEMAN Trial
NCT03322995 Pancreatic Cancer Adaptive Neoadjuvant Chemotherapy Trial
NCT06247995 A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.
NCT06422455 Access to Genetic Testing in Underserved Patients With Cancer
NCT06833255 A Post-treatment Supportive Service Program for the Transition Into Survivorship for Black Women Breast Cancer Survivors in Western New York
NCT05837455 NeoTAILOR: ABiomarker-directed Approach to Guide Neoadjuvant Therapy for Patients With Stage II/III ER-positive, HER2-negative Breast Cancer
NCT03699995 MoleMapper, Visiomed, and Confocal Microscopy in Screening Participants for Melanoma
NCT06772181 A Digital Health Intervention to Improve Symptoms and Physical Activity During Breast Radiation
NCT06066138 A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing
NCT04729114 A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer
NCT05013255 Pioglitazone Therapy Targeting Fatigue in Breast Cancer
NCT06136650 A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
NCT06544655 A Study of BMS-986484 Alone and Combination Therapy in Participants With Advanced Solid Tumors
NCT06220214 Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer
NCT06270043 Focal Therapy for Localized Prostate Cancer
NCT06494150 Nab-Sirolimus and Endocrine Therapy in Recurrent Low Grade Serous Ovarian Cancer (NARETO)
NCT06500455 Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
NCT06504914 Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors
NCT06659614 Prostate Tissue BioBank
NCT06782555 A Study of Evofosfamide in Combination with Zalifrelimab and Balstilimab
NCT05309655 Cardiac Outcomes With Near-Complete Estrogen Deprivation
NCT05841355 MADRE (Mammograms Available Due to Research and Education)
NCT06572410 Prospective Analysis of EnVisio Spatial Intelligence for Soft Tissue Localization and Guided Surgical Excision
NCT05603910 Phase 1 Clinical Trial of Lenvatinib, Pembrolizumab and Hypofractionated Pelvic Radiation Therapy for pMMR Recurrent/Unresectable Endometrial Carcinoma
NCT06585410 Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma
NCT01035112 Magnetic Resonance Imaging of Breast Cancer
NCT03701581 4-aminopyridine Treatment for Nerve Injury
NCT04754412 Culturally Based Brief Expressive Writing Intervention for the Improvement of Health in Chinese Immigrant Stage 0-III Breast Cancer Survivors, Writing to Heal Study
NCT05043012 Diagnostic Performance Of Non-Endorectal Coil Multiparametric Magnetic Resonance Imaging Of Prostate With Flexible AIR Coil (DoNEMAC Study)
NCT06690281 A Phase II Study of Adjuvant Immunotherapy Targeting KRAS G12D, KRAS G12V, or TP53 R175H for Participants With Advanced Gastrointestinal Malignancies
NCT05396612 Role of the Immune Environment in Response to Therapy in Breast Cancer
NCT02040610 Hypofractionated Image Guided Proton Therapy for Low andIntermediate Risk Prostate Cancer
NCT05691010 A Study of Short-Course Radiation Therapy With Chemotherapy in People With Endometrial Cancer
NCT03854110 Trial to Evaluate Safety and Tolerability of GP-2250 in Combination With Gemcitabine
NCT04389281 X-ray Psoralen Activated Cancer Therapy in Head and Neck, Breast, Sarcoma and Melanoma
NCT05979610 Using Reiki Therapy to Improve Symptoms Associated With Brachytherapy in Patients With Gynecological Malignancies
NCT06677112 MCC-24-GYN-11: Comparison of Nodal Sampling in Endometrial Cancer
NCT04645810 A Study of Focal Salvage High-Dose-Rate Brachytherapy for Prostate Gland Only Recurrence
NCT06671912 Testing Low Dose Tamoxifen for Invasive Breast Cancer, the (LoTam) Trial
NCT06111781 The SUGAR Study; SBRT and Relugolix) for Prostate Cancer
NCT05464810 Letrozole With and Without Simvastatin for the Treatment of Stage I-III Hormone Receptor Positive, HER2 Negative Breast Cancer
NCT05479812 Dose Escalation and Expansion Study of WTX-124 as Monotherapy and in Combination With Pembrolizumab (Pembro) in Patients With Selected Advanced or Metastatic Solid Tumors
NCT06070012 Tebentafusp in HLA-A*0201 Positive Previously Untreated Metastatic Uveal Melanoma
NCT06517212 Tirzepatide Weight Loss for MRD+ Early Breast Cancer
NCT04877912 Accurate, Rapid and Inexpensive MRI Protocol for Breast Cancer Screening
NCT06325046 Adaptive Radiation Therapy (ART) Stereotactic Ablative Body Radiotherapy (SABR) for Primary Localized Prostate Cancer
NCT05155046 18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy
NCT05629546 Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in Advanced or Metastatic Melanoma After Progression on Checkpoint Inhibitors
NCT05654246 Susan G. Komen's ShareForCures
NCT06882746 A Study to Test Different Doses of BI 765049 in People With Advanced Cancer of the Colon, Rectum, Stomach, or Pancreas
NCT06168812 A Study of Glipizide to Treat High Blood Sugar in People With Pancreatic Cancer
NCT05534646 Study of Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer
NCT04606446 Study of PF-07248144 in Advanced or Metastatic Solid Tumors
NCT05220046 Palliadelic Treatment to Reduce Psychological Distress in Persons With Advanced Gastrointestinal Cancers
NCT06305312 Community Services Navigation to Advance Health Equity in Breast Cancer Screening
NCT05080946 Using Aspirin to Improve Immunological Features of Ovarian Tumors
NCT03821246 Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy
NCT05058846 Pilot Study of Pancreatic Cancer Screening
NCT06079346 A Study of OT-101 With mFOLFIRINOX in Patients With Advanced and Unresectable or Metastatic Pancreatic Cancer
NCT05239546 Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon Cancers
NCT05396846 My Best GI Eating Study
NCT03897881 An Efficacy Study of Adjuvant Treatment With the Personalized Cancer Vaccine mRNA-4157 and Pembrolizumab in Participants With High-Risk Melanoma (KEYNOTE-942)
NCT03285412 CDK 4/6 Inhibitor, Ribociclib, With Adjuvant Endocrine Therapy for ER-positive Breast Cancer
NCT04812912 Changes in Reproductive and Sexual Health in People With Early Onset Colorectal Cancer
NCT06369246 PRORAD-5 PROstate RADiation in 5 Fractions: Phase Ib Five Fraction Radiotherapy for Patients With Advanced Prostate Cancer
NCT06518746 Gonadal Dysgenesis Tissue Cryopreservation for Fertility Preservation
NCT06074510 PYLARIFY® PET/CT or PET/MRI in Men With Favorable Intermediate Risk (FIR) Prostate Cancer
NCT05655312 MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma
NCT06787612 Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer
NCT06989112 DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
NCT05245812 Safety and Feasibility of Robotic SP Nipple Sparing Mastectomy
NCT06746012 Designing a Dyad-Based MHealth Intervention to Improve Adherence to Lifestyle Recommendations in Colorectal Cancer Survivors and Their Family Caregivers
NCT06818812 A Study to Evaluate INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
NCT05839912 Excision of Lymph Node Trial (EXCILYNT) (Mel69)
NCT05369546 Lesion Composition and Quantitative Imaging Analysis on Breast Cancer Diagnosis
NCT06378346 GU-01: Glycyrrhizin in Prostate Cancer
NCT02333604 Cancer Experience Registry (CER) for Cancer Patients and Caregivers
NCT06388304 THRIVE Study: Positive Affect Training for Endocrine Therapy Medication Adherence
NCT04044872 Hyperpolarized Carbon 13-Based Metabolic Imaging to Detect Radiation-Induced Cardiotoxicity
NCT01492972 Hypo-fractionated Radiation Therapy With or Without Androgen Suppression for Intermediate Risk Prostate Cancer
NCT04829604 ARX788 in HER2-positive, Metastatic Breast Cancer Subjects (ACE-Breast-03)
NCT05607004 (Z)-Endoxifen for the Treatment of Premenopausal Women With ER+/HER2- Breast Cancer
NCT02021604 Fluorodopa F 18 in Congenital Hyperinsulinism and Insulinoma
NCT06682390 Role of Race in Nutritional Approach in Men on ADT
NCT01794403 Radiation Hypofractionation Via Extended Versus Accelerated Therapy (HEAT) for Prostate Cancer
NCT06580743 Efficacy Verification in Early Diagnosis and Management of Lymphedema Through Home Body Water Analyzer
NCT06705803 Prostate Ablation Registry and Database for Information, Surveillance, and Evaluation (PARADISE)
NCT05663203 A Web-Based Dyadic Intervention for Colorectal Cancer
NCT06677190 Belzutifan in Recurrent Clear Cell Ovarian Carcinoma
NCT04725903 Proton Radiation Therapy for the Treatment of Patients with High Risk Prostate Cancer
NCT05005403 Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer (NSCLC), Head and Neck Squamous Cell Carcinoma (HNSCC) and Other Solid Tumors, Receiving Intravenous (IV) Infusion of Azirkitug (ABBV-514) Alone or in Combination With Budigalimab or Bevacizumab
NCT06666790 DermaSensor Postmarket Surveillance Study
NCT06523803 A Study of ZW171 in Participants With Advanced or Metastatic Mesothelin-expressing Cancers
NCT04916990 Improving Care for Rural Patients With Solid Tumors
NCT06179303 Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer
NCT06007690 A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma
NCT06349590 Manipulation of the Gut Microbiome by a Standardized Preoperative Diet to Prevent Colorectal Cancer Recurrence and Metastasis Following Surgery
NCT05700903 Contributions to Hypertension With Androgen Deprivation Therapy
NCT02381990 MRI/Ultrasound Fusion Guided Prostate Cryotherapy
NCT05381103 PSMA-PET to Guide Prostatectomy
NCT05826743 Safety and Effectiveness Evaluation of the COLO-BT as an Alternative Treatment to the Ileostomy
NCT02775643 Molecular Analysis of Childhood and Adolescent Melanocytic Lesions
NCT06016738 OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer
NCT06850623 Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer
NCT05732623 Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer
NCT04088708 Gut Microbe Composition, Exercise, and Breast Breast Cancer Survivors
NCT05720338 Is Intraperitoneal Drainage Necessary Following Distal Pancreatectomy?
NCT05665738 Two-fraction HDR Monotherapy for Localized Prostate Cancer
NCT03334708 A Study of Blood Based Biomarkers for Pancreas Adenocarcinoma
NCT03979508 Abemaciclib in Treating Patients With Surgically Resectable, Chemotherapy Resistant, Triple Negative Breast Cancer
NCT04929223 A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
NCT00001823 Evaluation for NCI Surgery Branch Clinical Research Protocols
NCT06476808 A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.
NCT06215508 Geriatric Assessment and Technology Evaluation in Prostate Cancer
NCT05055323 A Study to Determine if the Drug, Pyrvinium Pamoate, is Safe and Tolerable in Patients With Pancreatic Cancer
NCT05373823 MySmartSkin Online Skin Self-exam Intervention for Melanoma Survivors
NCT06675643 Digital Remote Monitoring of Immune Checkpoint Inhibitor Therapy Induced Toxicity: A Feasibility Study of the Vigilant App (Vigilant-2)
NCT06084338 Randomized Phase II Trial of Targeted Radiation With no Castration for Mcrpc
NCT03311308 A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma
NCT06151223 A Prospective Registry for Patients at High-Risk for Pancreatic Cancer
NCT03011684 Fertility Preservation Using Tamoxifen and Letrozole in Estrogen Sensitive Tumors Trial
NCT04821284 Sonoporation and Chemotherapy for the Treatment of Pancreatic Cancer
NCT03998202 Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer
NCT04038502 Carboplatin or Olaparib for BRcA Deficient Prostate Cancer
NCT02945579 Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy
NCT05870579 [177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With ER+, HER2- and GRPR+ Advanced Breast Cancer
NCT05524584 Anastrazole, Fulvestrant & Abemaciclib for HR+HER2- Metastatic Breast Cancer
NCT04762979 Alpelisib (BYL719) in Combination With Continued Endocrine Therapy Following Progression on Endocrine Therapy in Hormone Receptor Positive, HER2 Negative, PIK3CA Mutant Metastatic Breast Cancer
NCT06112379 A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer
NCT06238479 A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors
NCT02594202 Care of the Prostate Cancer Patient and Prospective Procurement of Prostate Cancer Tissue
NCT05633979 Phase 1b Study of EZH1/2 Inhibitor Valemetostat in Combination With Trastuzumab Deruxtecan in Subjects With HER2 Low/Ultra-low/Null Metastatic Breast Cancer
NCT06237179 Behavioral Exercise Training to Reduce Cardiovascular Disease Risk
NCT04683679 A Study of Radiation Therapy With Pembrolizumab and Olaparib or Other Radiosensitizers in Women Who Have Triple-Negative or Hormone-Receptor Positive/Her2 Negative Breast Cancer
NCT04933084 Pre-operative Education Modalities to Decrease Opioid Use
NCT05419479 Switch Maintenance in Pancreatic
NCT06831084 Acute Radiation Dermatitis After Adjuvant Radiotherapy for Breast Cancer Patients With the Use of Silver-Plated Technology
NCT04080284 Trial of Maintenance With Niraparib- Uterine Serous Carcinoma
NCT06321484 Intraperitoneal Cytokine-Induced Memory Like (CIML) Natural Killer (NK) Cells in Recurrent Ovarian Cancer
NCT06750484 Trial of Trastuzumab Deruxtecan in Previously Treated HER2
NCT05923684 NLP-Based Feedback to Improve Risk Comms and Informed Shared Decision Making
NCT06016855 Surgical Debulking Prior to Peptide Receptor Radionuclide Therapy in Well Differentiated Gastroenteropancreatic Neuroendocrine Tumors
NCT06014255 Trial of Neoadjuvant Enoblituzumab vs SOC in Men With High-Risk Localized Prostate Cancer
NCT05676255 The Breast Cancer Survivors and Partners Online Research Together (SUPORT) Project
NCT05530655 A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate Cancer
NCT06943755 Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
NCT06938555 The RolE of Prolonged Nightly faSTing to Improve Sleep and cOgnition in bREast Cancer Survivors
NCT06617455 Fezolinetant for the Improvement of Vasomotor Symptoms in Breast Cancer Patients Taking Endocrine Therapy, VENT Trial
NCT04273555 Monitoring Early Response to Targeted Therapy in Stage IV HER2+ Breast Cancer Patients with Advanced PET/MR Imaging
NCT06682650 Implementation of a ColoRectal Cancer Screening Tool in US Primary Care Practices - Usual Quality Improvement (10 Clinics) vs Normalization Process Theory-Participatory Learning in Action (10 Clinics)
NCT04291755 Development and Analysis of a Stool Bank for Cancer Patients
NCT05413850 Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection
NCT06332755 Study to Evaluate LB-LR1109 for the Treatment of Solid Tumors
NCT04144023 A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ
NCT06733350 Testosterone Replacement Therapy for the Treatment of Low Testosterone in Hypogonadal Men With Localized Prostate Cancer on Active Surveillance
NCT06470750 Feasibility of Patient-Centered Home Care (PCHC) to Reduce Disparities in High-Risk Black Men (BM) with Advanced Prostate Cancer (CaP)
NCT05692323 A Supervised Prehabilitation Program for Patients With Pancreatic Cancer
NCT05779423 Cryoablation+Ipilimumab+Nivolumab in Melanoma
NCT06636123 GZ17-6.02 in Advanced CRPC After Progression on Anti-Androgen Therapy
NCT04348123 Interventional Program Educates, Identifies + Overcomes Barriers to Complete Screening Mammography
NCT06216938 RP1 in Primary Melanoma to Reduce the Risk of Sentinel Lymph Node Metastasis
NCT04915508 Extremely Hypofractionated Intensity Modulated Stereotactic Body Radiotherapy for the Treatment of Prostate Cancer With Rising PSA After Radical Prostatectomy
NCT05919108 Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers
NCT05477823 Imaging and Genomic Biomarkers to Predict Response in Prostate Cancer
NCT05512208 A Phase 2 Study of Avutometinib (VS-6766) Plus Defactinib
NCT05806138 A Study of Vericiguat in People With Breast Cancer and Cancer Therapy-Related Cardiac Dysfunction
NCT06529523 Tislelizumab in People With Colorectal Cancer
NCT06153238 A PK Study to Compare GME751 (Proposed Pembrolizumab Biosimilar) and US-licensed and EU-authorized Keytruda® in Participants With Stage II and III Melanoma
NCT05417308 Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV Breast Cancer
NCT04396808 Genomics in Michigan to AdJust Outcomes in Prostate canceR (G-MAJOR) for Men With Newly Diagnosed Favorable Risk Prostate Cancer
NCT04996823 Axitinib + Ipilimumab in Advanced Melanoma
NCT04541108 Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies
NCT05386108 Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to ER+/HER-2- Breast Cancer
NCT05259410 Time Restricted Eating During Chemotherapy for Breast Cancer
NCT06369610 Risk Stratified De-escalated Hormone Therapy With Radiation Therapy for the Treatment of Prostate Cancer
NCT05827081 Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
NCT04636710 Refining Local-Regional Therapy for IBC
NCT05230810 Clinical Trial of Alpelisb and Tucatinib in Patients With PIK3CA-Mutant HER2+ Metastatic Breast Cancer.
NCT05241210 Real-Time Feedback (RTFB) to Improve Colonoscopy
NCT05248581 Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases
NCT05138510 Sexual Health in Breast Cancer Patients
NCT06075810 A Study of Oral MBQ-167 in Participants With Advanced Breast Cancer
NCT04866810 The Effect of Diet and Exercise on ImmuNotherapy and the Microbiome (EDEN)
NCT06412510 Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT
NCT06072612 Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
NCT04541381 The PhOCus Trial: Implementation of Pharmacogenomic Testing in Oncology Care
NCT06026410 KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
NCT06541210 Building Community Living Labs in Black Communities to Advance Prostate Health Equity and Reduce Prostate Cancer Disparities in Black Men
NCT02170181 Clinical Registry for Oligometastic Disease, Consolidation Therapy, Debulking Prior to Chemotherapy, or Re-Irradiation
NCT06749210 DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY
NCT05659381 Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer
NCT06516510 A Dosimetry Study of Lutetium (177Lu) rhPSMA-10.1 and Lutetium (177Lu) Vipivotide Tetraxetan (Pluvicto®) in Patients With Non-curative Metastatic Prostate Cancer
NCT05098210 Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer
NCT06612281 Evaluation of Gixam's Performance in a FIT Negative Population
NCT06536881 Gut Microbiome, Adverse Effects, and Markers Through MEtabolic Reprogramming
NCT05269381 Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
NCT06036810 Spanish Decision Tool for Ovarian Cancer Maintenance Therapy
NCT06528210 Pembrolizumab With Androgen Deprivation Therapy and Radiotherapy for the Treatment of Patients With High Risk Localized Prostate Cancer
NCT06173310 DCE-MRI Guided Neoadjuvant Chemotherapy for Borderline Resectable Pancreatic Cancer
NCT05366881 cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
NCT05900895 Estradiol Plus Olaparib for Breast Cancer (PHOEBE)
NCT05365581 A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer
NCT06084481 Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400
NCT05568550 Pembro With Radiation With or Without Olaparib
NCT05687123 Testing the Addition of Sunitinib Malate to Lutetium Lu 177 Dotatate (Lutathera) in Pancreatic Neuroendocrine Tumors
NCT06096623 The Care Tracker Study: Using Patient-Reported Data to Address Racial Disparity in Cancer Treatment
NCT06006923 Regorafenib in Combination With Pembrolizumab or Pembrolizumab for MSI-H Colorectal Cancer
NCT06234423 A Study of CUSP06 in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors
NCT05447923 Addressing Disparities in Colorectal Cancer Screening in Black and Underserved Phoenix Communities
NCT05483023 18-fluorofuranylnorprogesterone (FFNP) PET/MRI as a Potential Biomarker of Response to Progesterone Therapy
NCT02313623 MR-US Image Fusion Targeted Biopsy for Single-cell Prostate Cancer Research
NCT06058650 Molecular Breast Imaging Guidance for Breast Biopsy for Patients With Breast Abnormalities
NCT05534438 A Study on Adding Precisely Targeted Radiation Therapy (Stereotactic Body Radiation Therapy) to the Usual Treatment Approach (Drug Therapy) in People With Breast Cancer
NCT01607008 MRI for Assessing Prostate Cancer Response
NCT06831838 A Randomized Controlled Trial (RCT) to Determine the Efficacy of a Multidisciplinary CBT Based Pain Management Program for the Treatment of Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS) in Breast Cancer Survivors
NCT06864338 Pilot Study for Colorectal Cancer and Advanced Adenoma Detection With the Mainz Biomed Colorectal Cancer Test
NCT06981208 ChatGPT & Surgeon Synergy: Redefining Breast Reconstruction Consultations for Enhanced Patient Engagement and Satisfaction
NCT05871008 Integrated Actionable Aging Assessment for Cancer Patients Pilot
NCT04899908 Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases
NCT06534008 Strive Cardio for Endometrial Cancer Survivors
NCT04517838 Immune Response to Anti-HER2 Therapies in Patients With HER2-Positive Stage I-IV Breast Cancer
NCT06328738 ELVN-002 with Trastuzumab +/- Chemotherapy in HER2+ Solid Tumors, Colorectal and Breast Cancer
NCT05327608 Neoadjuvant Breast Cancer Time Restricted Eating
NCT05155501 Clinical Trial of Approaches to Prostate Cancer Surgery
NCT04783467 Time Restricted Eating (TRE) Among Endometrial Cancer Patients
NCT04674267 Resilience and Equity in Aging, Cancer, and Health (REACH)
NCT04474301 Well-Being and Health-Related Quality of Life in Melanoma Patients During COVID-19 Pandemic
NCT06521567 A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer
NCT05367440 Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer
NCT04090567 Olaparib With Cediranib or AZD6738 for the Treatment of Advanced or Metastatic Germline BRCA Mutated Breast Cancer