Prostate Cancer


Relevance: High
Most relevant for: Men and women diagnosed with breast cancer who have a BRCA1 or BRCA2 mutation
Study: Understanding the risks of a second cancer after a breast cancer diagnosis in people with BRCA1 and BRCA2 mutations
After breast cancer, people who have a BRCA1 or BRCA2 mutation face a greater risk of a second cancer compared to individuals without a BRCA mutation. This study helps to better understand this risk so that breast cancer survivors with mutations can receive informed, personalized plans for surveillance and follow-up care. (Posted 12/11/25)
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Relevance: High
Most relevant for: People with metastatic castration-resistant prostate cancer
Study: Combination treatment for metastatic castration-resistant prostate cancer may be especially effective for people with BRCA1 or BRCA2 mutations
This review summarizes the results of the TALAPRO2 study. It looked at how well the PARP inhibitor Talzenna (talazoparib) works for treating metastatic castration-resistant prostate cancer (mCRPC). Talzenna appears to be most effective for people with BRCA1 or BRCA2 mutations but is also effective for people with certain other mutations. (posted 9/30/25)
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Relevance: Medium-High
Most relevant for: Men with West African ancestry
Study: Neighborhood affects prostate cancer risk in men of West African ancestry
Black men of West African genetic ancestry have a much higher risk of developing prostate cancer than men of other races. The risk is even greater when they live in deprived or disadvantaged neighborhoods. (Posted 2/26/25)
Este artículo está disponible en español.
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Relevance: Medium-High
Most relevant for: People at high risk for hereditary cancer
Guideline: Hereditary cancer gene guidelines expand
The National Comprehensive Cancer Network regularly updates guidelines for several types of hereditary cancer. These recommendations often change when new research is published. Recently, the NCCN expanded its guidelines to include information on hereditary prostate and gastric cancers. (Posted 1/6/25)
Este artículo está disponible en español.
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Relevance: Medium-High
Most relevant for: People with cancer interested in using cannabis to help manage symptoms.
Study: Use of cannabis for cancer symptom management
Among people with cancer, interest in the use of cannabis to manage cancer symptoms and treatment side effects is high. The world's leading professional organization of oncologists has published strategies to help adults with cancer and their healthcare providers have open, nonjudgmental discussions about the use of cannabis to manage cancer symptoms. (Posted 9/27/24)
Este artículo está disponible en español.
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Relevance: Medium
Most relevant for: People with prostate cancer
Update: News from the FDA: First-line treatment and biosimilars for prostate cancer
The FDA recently approved a first-line treatment for non-metastatic, castration-sensitive prostate cancer. Approval was also given to two new drugs known as biosimilars that can be used in place of two already approved biologics to prevent bone weakening, pain or fractures that may occur from certain hormone therapies or from cancer that has spread to the bone. (Posted 9/10/24)
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Relevance: High
Most relevant for: People diagnosed with cancer
Topic: Acupressure for cancer symptom relief
Acupressure is a safe treatment that can be used to relieve some symptoms of cancer and side effects of treatment. Light pressure applied to key points on the body may help with fatigue, sleep, nausea and possibly other symptoms as well. (Posted 8/1/24)
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Relevance: Medium-High
Most relevant for: People with advanced HER2-positive cancer
Topic: The drug Enhertu is FDA-approved for any advanced or metastatic HER2-positive tumors
The FDA granted accelerated approval of Enhertu for people with any HER2-positive tumor that is metastatic or cannot be surgically removed. Eligible patients must have had previous treatment such as chemotherapy or hormone therapy. (Posted 7/19/24)
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Relevance: Medium-High
Most relevant for: Cancer patients
Topic: Experts call for early palliative care for cancer patients
People with cancer need support and care not only at the end of life but from the time of diagnosis. At the 2024 American Society of Clinical Oncology (ASCO) annual meeting, the organization’s president urged cancer healthcare professionals to make palliative care central to cancer treatment. (Posted 7/17/24)
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Relevance: High
Most relevant for: People diagnosed with cancer who have not yet had genetic testing
Study: Genetic testing among people with cancer can find mutations that may affect treatment and prevention
Despite national guidelines recommending genetic testing, less than 10 percent of eligible patients had genetic testing within two years after their cancer diagnosis. Among those who had testing, 10-30 percent had an inherited mutation that could affect their medical care. (Posted 3/15/2024)
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