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Education > XRAY > Metastatic Breast Cancer

FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
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Metastatic Breast Cancer

1 through 10 of 109

Relevance: Medium

Update : News from the FDA– new breast cancer treatment, thermography warning and implant screening updates

Most relevant for: People with HR-positive and HER2-negative metastatic breast cancer. People with silicone breast implants. People considering thermography screening

This XRAY review is a summary of FDA breast cancer updates from July to December 2023.  This includes a new drug approval and two consumer updates. (Posted 2/21/24)

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Relevance: Medium-High

Research Timeline: Post Approval

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Update : New drug combination for the second treatment of some HR-positive advanced breast cancers

Most relevant for: People with hormone receptor (HR)-positive or HER2-negative breast cancer that has spread outside the breast tissue.

The FDA approved Truqap plus Faslodex for the treatment of metastatic hormone receptor-positive (HR-positive), HER2-negative breast cancer that returned or worsened after treatment with hormone therapy. The approval is for treating cancers in people whose tumors had a mutation in one of three genes. For people with one of these mutations, Truqap improved the time until their cancer came back or got worse.  (Posted 2/9/24)

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Relevance: High

Quality of Writing: Medium-High

Article : Genetic testing and the future of medicine

Most relevant for: People interested in genetic testing.

An article published in Katie Couric Media discusses genetic testing and how it can impact health. The author talked with Dr. Robert Steiner, a doctor who specializes in genetics. He talked about genetic testing and how the results can affect health and change lives. (Posted 9/28/23)

Este artículo está disponible en español.

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Relevance: Medium-Low

Quality of Writing: Medium

Research Timeline: Animal Studies

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Article : Promising drug for cancer treatment begins clinical trials

Most relevant for: People with solid tumors.

Researchers at City of Hope are testing a new type of cancer treatment drug. When tested in animals and cells taken from human cancers, this new drug prevented the growth of many types of cancer. Initial clinical trials in people have just started. (Posted 9/7/23)

Este artículo está disponible en español.

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Relevance: Medium-High

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Topic : Sex and intimacy after breast cancer

Most relevant for: People with breast cancer or metastatic breast cancer in sexual or intimate relationships and their partners

A breast cancer diagnosis and treatment can affect relationships with romantic partners. This review highlights two studies that looked at how people with breast cancer and their partners are affected, how they cope, how best to communicate with each other and how to talk with healthcare providers about concerns related to cancer and sexuality. (Posted 8/8/23)

Este artículo está disponible en español.

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Relevance: Medium

Topic : Impact of new laws on cancer treatment during pregnancy

Most relevant for: People who have cancer who are pregnant

The U.S. Supreme Court ruled in 2022 that abortion is no longer a protected right under the Constitution.  This landmark decision leaves regulation of abortion to the states. Cancer treatment during pregnancy may now be impacted in states that have abortion bans or limitations. (Posted 5/31/23)

Este artículo está disponible en español.

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Relevance: High

Strength of Science: Medium-High

Research Timeline: Post Approval

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Study : Breast cancer outcomes improved with CDK4/6 inhibitor treatment

Most relevant for: People with HR-positive HER2-negative advanced breast cancer

A study showed that people with metastatic breast cancer who took an oral drug known as a CDK4/6 inhibitor combined with hormone therapy did better than people who took hormone therapy alone. The drug combination improved the length of time before cancer worsened or returned. After six years of treatment, people who took this drug combination lived longer compared to those who took hormone therapy alone. (Posted 4/5/23)

Este artículo está disponible en español.

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Relevance: High

Strength of Science: High

Research Timeline: Post Approval

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Study : New oral drug treatment for some advanced breast cancer

Most relevant for: People with HR-positive, HER2-negative advanced breast cancer

The FDA has approved a new oral drug called Oserdu for the treatment of HR-positive, HER2-negative advanced breast cancer. A blood test was also approved to help doctors identify patients who would benefit most from this new treatment. (Posted 3/20/23)

Este artículo está disponible en español.

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Relevance: Medium-High

Strength of Science: High

Research Timeline: Post Approval

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Study : Trodelvy benefits people with advanced hormone-positive metastatic breast cancer

Most relevant for: People with ER/PR-positive, HER2-negative metastatic breast cancer

The study TROPiCS-2 showed that the drug Trodelvy (sacituzumab govitecan) improved progression-free survival when compared to chemotherapy in people with advanced metastatic ER/PR-positive, HER2-negative breast cancer who have few other treatment options. This drug does not yet have FDA approval for use in the hormone-positive setting. (Posted 1/18/23)

Update: On 02/03/2023 the FDA approved Trodelvy for patients with locally advanced or metastatic  breast cancer who have received hormonal therapy and at least two other types of treatment in the metastatic setting.

Este artículo está disponible en español.

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Relevance: High

Strength of Science: High

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Topic : Cancer disparities in American Indian and Alaska Native populations

Most relevant for: Americans Indians and Alaska Natives

The American Cancer Society released a special section in their 2022 Cancer Facts & Figures report that discussed cancer disparities in American Indian and Alaska Native populations in the United States. This review highlights the special section’s main points, including disparities in cancer screening, diagnosis and survival rates in native communities, as well as factors contributing to those disparities. (Posted 12/20/22)

Este artículo está disponible en español.

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