Education > XRAY > Prostate Cancer

FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
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1 through 10 of 54

Relevance: Medium-High

Strength of Science: Medium-High

Research Timeline: Human Research

Study : PARP inhibitor treatment for metastatic prostate cancer shows most benefit in men with inherited BRCA mutations

Most relevant for: People with metastatic castration resistant prostate cancer who have an inherited or tumor mutation in BRCA2.

This study looked at the benefit of using the PARP inhibitor niraparib to treat metastatic castration-resistant prostate cancer (mCRPC). Participants included those with an inherited or tumor mutation in BRCA1 or BRCA2 or an inherited or tumor mutation in another gene that affects DNA repair. Participants with an inherited or tumor mutation in BRCA1 or BRCA2 had better survival compared to those without a BRCA mutation. Side effects from niraparib were common, and consistent with previous reports for PARP inhibitors.  (posted 9/6/2022)

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Relevance: Medium-High

Strength of Science: High

Research Timeline: Post Approval

Study : Physical activity may decrease fatigue associated with cancer treatment

Most relevant for: Cancer patients who are experiencing fatigue related to cancer or its treatment.

Many cancer survivors experience fatigue during and after they complete treatment. This study looked at the effect of home-based physical activity on fatigue in cancer survivors. It also looked at whether frequent counseling encouraged people to start and continue their exercise routines.  (Posted 8/1/22)

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Relevance: High

Strength of Science: Medium-High

Research Timeline: Post Approval

Study : The hidden financial burden of treating cancer care symptoms

Most relevant for: People who are experiencing side effects due to cancer treatment or cancer.

Drugs commonly used to treat symptoms of cancer and cancer treatment side effects can cost thousands of dollars out of pocket for patients, depending on what drugs are used. (Posted 6/29/2022)

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Relevance: Medium

Strength of Science: Medium

Research Timeline: Post Approval

Study : Do artificial sweeteners increase the risk of cancer?

Most relevant for: People who consume artificial sweeteners

A large study of adults in France suggests that artificial sweeteners may increase the risk of certain cancers. (posted 6/21/2022)

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Relevance: Medium-High

Strength of Science: Medium-High

Research Timeline: Post Approval

Study : Metastatic prostate cancer cases increased as screening use declined

Most relevant for: People who are concerned about their own or their loved one’s risk of prostate cancer

The number of people diagnosed with metastatic prostate cancer increased following a change in recommendations around the use of routine prostate cancer screening. (posted 6/13/22)

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Relevance: Medium-High

Research Timeline: Post Approval

Update : New drug approved for metastatic prostate cancer

Most relevant for: People who have been diagnosed with metastatic prostate cancer.

The FDA approved a new treatment for metastatic castration-resistant prostate cancer. They also approved a test that can be used to identify patients who would benefit from this new treatment.  (Posted 5/10/22)

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Relevance: Medium

Strength of Science: Medium-High

Research Timeline: Post Approval

Study : Increasing melatonin use raises concerns

Most relevant for: people who take or consider taking melatonin to help with sleep.

Adult use of melatonin as a sleep aid has increased even though its benefits and risks are not well understood. This study looked at trends in melatonin use over the last 19 years. (Posted 4/14/2022)

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Relevance: Medium-High

Strength of Science: Medium-High

Research Timeline: Human Research

Study : Cannabis use among breast cancer patients

Most relevant for: People interested in using cannabis to relieve treatment side effects.

This study looked at patterns of cannabis use among breast cancer patients who are members of online health communities. Almost half of the study participants reported using cannabis to help manage treatment symptoms and side effects. The study also looked at reasons why patients used cannabis, where they obtained it and whether they perceived cannabis to be safe. While this study only looked at cannabis use among breast cancer patients it is likely results would be similar among patients diagnosed with other types of cancers. (posted 1/25/22)

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Relevance: High

Research Timeline: Post Approval

Most relevant for: People with cancer considering a COVID-19 booster

The National Comprehensive Cancer Network has issued new guidelines for COVID-19 vaccinations. Guidelines now recommend a booster or third dose of the Pfizer-BioNTech or Moderna vaccine for patients with cancer, including those undergoing active treatment. Currently, these updated guidelines do not address people who had the one-dose Johnson & Johnson vaccine. (posted 11/16/2021)

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Relevance: Medium-High

Strength of Science: High

Research Timeline: Human Research

Study : Bone-protecting drugs cut the risks for fractures caused by metastatic prostate cancer treatments

Most relevant for: People with metastatic castration resistant prostate cancer

Skeletal problems, especially bone fractures, are common in patients with advanced prostate cancer. To prevent these, many guidelines recommend the use of bone-protecting agents during treatment. The importance of giving a bone-protecting agent when treating patients with metastatic castration-resistant prostate cancer and bone metastases was confirmed in early results of an ongoing phase III trial. (11/5/21)

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