|Chemotherapy and hair loss||Clinical trials|
|Coping with hair loss||Questions for your doctor|
|Treating hair loss||Resources and reference|
When Stephanie Hess was diagnosed with stage III ovarian cancer, she knew what to expect. She had watched her mother and other family members cope with the side effects of chemotherapy.
“Because my mom had passed away from cancer, I knew what it felt like. The thought of losing your hair, that’s the ultimate indicator of being a cancer patient.” she says. “I didn’t want to be bald.”
Hair loss is often the most common and visually striking side effect of chemotherapy, especially for women with cancer. Many different types of chemotherapy drugs cause hair loss.
Both men and women report that hair loss is one of the side effects of chemotherapy they fear most. Studies show that 58 percent of patients consider hair loss the worst side effect of chemotherapy, and that up to eight percent consider not having treatment for fear of losing their hair. Chemotherapy may also cause changes in hair texture, quality, amount and color.
Studies show that women undergoing chemotherapy more often have hair loss than men. For women, hair can represent their identity, personality, sexuality and femininity. Women also report a more negative body image as well as lower psychological, social, physical and emotional well-being than women who do not lose their hair.
Chemotherapy does not discriminate
Chemotherapy drugs are powerful. They attack any rapidly growing cells. While cancer cells usually grow quickly, some normal cells, like hair cells, do as well.
Because hair cells are present all over the human body, chemotherapy can also lead to loss of eyebrow, facial and pubic hair. The type and amount of chemotherapy affects how much hair is lost during treatment.
Usually, hair begins falling out two to four weeks later after chemotherapy begins. It may fall out in clumps or may gradually thin. Your scalp may also be tender. Hair loss usually continues throughout chemotherapy and may continue up to a few weeks after treatment ends. Hair typically grows back once chemotherapy is over. However, hair that returns is likely to have a different texture or color than the hair you lost. This difference is usually temporary.
Like Hess, some cancer patients choose to embrace their new look. And sometimes, like Hess’s family members, loved ones show support by going bald too.
Hess said, “My cute seven-year-old son shaved his head about two weeks after I shaved mine. I had a nephew that was living in Las Vegas at the time, and he had shaved his head for me.”
Her nieces also shaved their heads. “I hadn’t asked them to. I had no idea,” she recalls. “I got a text with their shaved heads, and I just cried and cried because it was so freeing.”
Hess went out to dinner with her niece and her newly shaved head. “She didn’t wear a hat or a scarf or anything. She was completely bald. Walking into that restaurant with my niece who was bald helped me to be less afraid.
Several hair loss treatments have been studied, but none has proven to completely prevent hair loss during or after chemotherapy.
Scalp cooling caps
Scalp cooling, sometimes called scalp hypothermia, is a treatment given while a person receives chemotherapy. A cap that is cooled by liquid is placed on your head. Scalp hypothermia works by slowing blood flow to the scalp and reducing the effect of chemotherapy drugs on rapidly growing hair cells. Scalp cooling may be more effective for certain types of chemotherapy.
Studies of scalp cooling show that it helps to reduce hair loss in most people who try them. Side effects of scalp cooling include being very cold and headaches. Two scalp cooling caps, DigniCap and Paxman Cooler, are approved by the FDA.
Scalp cooling costs between $1,500 and $3,000 per treatment. While insurance companies often partially cover the costs of wigs and other head coverings, they do not currently cover the cost of scalp cooling.
To learn more about scalping cooling read our XRAY review.
Rogaine is an FDA-approved drug approved for hair loss. It is a cream that is applied to your scalp before and during chemotherapy. While Rogaine is unlikely to prevent hair loss, some research has shown that it may speed hair regrowth.
Bimatoprost, like Rogaine, is a cream that is applied to eyelashes. Bimatoprost has been shown to be effective in treating chemotherapy-induced eyelash loss.
Giving a face to chemotherapy-induced hair loss
The impact of hair-loss is often underestimated by healthcare providers. New research from the Netherlands may help. It shows that patients’ drawings of their chemotherapy-induced hair loss may better portray their feelings before, during and after the experience than traditional methods like questionnaires. The drawings may be a way for healthcare providers to better understand their patient’s knowledge and understanding of chemotherapy-induced hair loss and how they cope with the experience.
For many, hair loss can be frustrating and stressful. Hess felt that by embracing her hair loss it empowered her. She sees her hair loss as a temporary setback rather than a permanent problem and hopes that her story can help some women make peace with their own experience.
Hess’s advice, “Find a support group. Talk to a group of people who understand what you are going through.”
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This article is relevant for:
People who receive chemotherapy for cancer treatment
This article is also relevant for:
Breast cancer survivors
Men with breast cancer
Ovarian cancer survivors
Women under 45
Women over 45
Pancreatic cancer survivors
Prostate cancer survivors
Be part of XRAY:
- Will my treatment result in temporary hair loss?
- Will my hair likely grow back the way it was before?
- Are there any treatments to reduce hair loss during chemotherapy or to help hair regrow after chemotherapy?
- What is scalp cooling?
- What side effects can occur after scalp cooling?
- How much does scalp cooing cost? Will it be covered by my health insurance?
- What other side effects should I expect from chemotherapy?
Any type of cancer
- NCT02296450. Quality of Life (QoL) Assessment in Cancer Patients and Survivors With Dermatologic Conditions Using Dermatologic QoL Instruments. This large study is designed to see how skin conditions that are related to different kinds of cancer or cancer treatments affect a patient's overall well-being.
- NCT04459650: A Study of platelet-rich plasma (PRP) Treatment for Hair Loss After Cancer Therapy in Women With Breast Cancer. This is a small study for female breast cancer patients with hair loss due to hormonal therapy or chemotherapy. Participants will have a sample of blood collected and the platelets injected into participants' scalp every 4 weeks for 12 weeks.
- NCT04180579. Safety of Lower Scalp Cooling Temperature to Prevent Hair Loss From Chemotherapy in Breast Cancer Patients. This small study will see where using the Paxman Scalp Cooling System at temperatures lower than the current standard is a safe and tolerable approach to prevent hair loss in breast cancer patients receiving chemotherapy.
- NCT04492800. Hair Loss Prevention Study for Pancreatic Cancer. This is a pilot study looking at the use of the Paxman scalp cooling device for prevention of hair loos in patients with pancreatic cancer who are receiving chemotherapy.