All XRAYs
Relevance: Medium
Most relevant for: People with multiple myeloma or who have families with multiple myeloma
Study: Hereditary cancer mutations among people with multiple myeloma
People with multiple myeloma who have inherited gene mutations are more likely to have had another cancer previously and may respond better to certain treatments than people with multiple myeloma who do not have inherited mutations. Individuals with an inherited BRCA1 and BRCA2 mutation may have a slightly increased risk for multiple myeloma, but more research is needed to confirm this. (Posted 4/23/25)
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Relevance: Medium-High
Most relevant for: People with colorectal cancer or at risk of colorectal cancer
Update: News from the FDA: Colorectal cancer screening and treatment
This XRAY review is a summary of FDA colorectal cancer (CRC) updates in the last year, including education regarding CRC screening, three treatment drugs targeting different types of CRC and two colorectal screening tests. (Posted 4/16/25)
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Relevance: Medium-High
Most relevant for: Premenopausal women before or during early breast cancer treatment
Update: Ovarian suppression may reduce breast cancer recurrence
Ovarian suppression—blocking estrogen production in the ovaries—can improve breast cancer outcomes in premenopausal women. This review provides information about ovarian suppression and describes who might benefit. (Posted 3/6/25)
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Relevance: Medium-High
Most relevant for: Young women with breast cancer concerned about survivorship issues
Topic: Addressing the needs of young adults with breast cancer
This update addresses common concerns faced by young adults with breast cancer, particularly fertility and childbearing, psychosocial health and treatment-related side effects. (Posted 2/28/25)
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Relevance: Medium-High
Most relevant for: Men with West African ancestry
Study: Neighborhood affects prostate cancer risk in men of West African ancestry
Black men of West African genetic ancestry have a much higher risk of developing prostate cancer than men of other races. The risk is even greater when they live in deprived or disadvantaged neighborhoods. (Posted 2/26/25)
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Relevance: Medium-High
Most relevant for: People with an inherited mutation that increases cancer risk who are interested in sexual health
Study: Impact on sexual well-being among people with an inherited BRCA mutation
This study looked at sexual well-being in those with an inherited BRCA1 or BRCA2 mutation. Knowledge about having an inherited BRCA1 or BRCA1 mutation did not influence sexual health. However, menopause and cancer diagnosis was had a significant impact on sexual health and sexual function. (Posted 2/13/25)
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Relevance: Medium-High
Most relevant for: People with a BRCA1 or BRCA2 mutation who have had risk-reducing surgery to remove their ovaries
Study: Risk of peritoneal cancer is low for people with an inherited BRCA mutation after surgery
The risk of peritoneal cancer is low in people with an inherited BRCA1 or BRCA2 mutation after risk-reducing ovary removal (oophorectomy). The risk was even lower when risk-reducing surgery was done at a young age and after 2005 when removal of the fallopian tubes was included in the procedure. The findings of this research support the theory that like ovarian cancer, peritoneal cancer begins in the fallopian tubes and reinforces the age recommendation for surgery. (Posted 1/23/25)
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Relevance: Medium
Most relevant for: People with an inherited mutation in CDKN2A
Article: Life with a high-risk pancreatic and melanoma cancer mutation
One woman seeks genetic testing after her sister died of pancreatic cancer. Despite how her family’s mutation in the CDKN2A gene resulted in multiple cancer diagnoses and deaths and a suspicious finding during her own pancreatic cancer screening, Amarensia Spruitenburg shares a message of hope and gratitude. By telling her story, Amarensia highlights the impact that hereditary cancer can have on families. (Posted 11/22/24)
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Relevance: Medium-High
Most relevant for: People with breast cancer who are interested in using exercise to reduce risk of recurrence
Study: Moderate exercise delays time to breast cancer recurrence
For premenopausal women with early-stage breast cancer, physical activity may increase the time before cancer returns and spreads. In this study, people with hormone receptor-negative (HR-negative) breast cancer benefited from moderate exercise—more than those with hormone receptor-positive (HR-positive) breast cancer. This study found that outcomes improved when weekly exercise time was between 90 minutes and 5 hours. (Posted 11/14/24)
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Relevance: Medium-High
Most relevant for: People with endometrial cancer
Update: News from the FDA: New endometrial cancer approvals
The FDA recently approved three new immunotherapy treatments (Jemperli, Imfinzi and Keytruda) for advanced endometrial cancer. (Posted 11/7/24)
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