Education > XRAY > Pancreatic Cancer

FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
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11 through 20 of 38

Relevance: High

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Research Timeline: Post Approval

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Update : Genetic causes of hereditary pancreatic cancer: BRCA and beyond

Most relevant for: People diagnosed with pancreatic cancer

An update on hereditary pancreatic cancer presented at the annual American Society of Clinical Oncology meeting covered genes and lifetime risk. The update emphasized that all pancreatic cancer patients should be offered genetic counseling and testing. Genetic test results may impact treatment, screening for other cancers and risk to family members. (11/26/19)

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Genetic causes of hereditary pancreatic cancer: BRCA and beyond

Relevance: High

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Strength of Science: Medium

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Research Timeline: Post Approval

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Study : Supportive care can improve quality of life for people with metastatic breast cancer

Most relevant for: People diagnosed with metastatic breast cancer

Metastatic breast cancer patients have unique needs for treatment and care. Connecting patients to appropriate support services and palliative care is an area of need in health care. A recent study reported improvement in metastatic breast cancer patient quality of life and wellness with an intervention program called the Supportive, Education and Advocacy (MBC-SEA) program. (8/21/19)

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Supportive care can improve quality of life for people with metastatic breast cancer

Relevance: High

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Strength of Science: High

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Research Timeline: Human Research

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Study : Results from the POLO trial: Olaparib may delay cancer progression in metastatic pancreatic cancer patients with BRCA mutations.

Most relevant for: People diagnosed with pancreatic cancer who have a BRCA mutation

Note: On 12/27/19, the FDA approved olaparib for treatment of pancreatic cancer in people with a BRCA mutation based on the results of the POLO study.

The POLO clinical trial looks at whether the PARP inhibitor olaparib improves outcomes for those with metastatic pancreatic cancer after platinum-based chemotherapy.  (7/3/19) 

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Results from the POLO trial: Olaparib may delay cancer progression in metastatic pancreatic cancer patients with BRCA mutations.

Relevance: Medium-High

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Strength of Science: High

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Research Timeline: Post Approval

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Study : LGBTQ patients recommend improvements for their cancer care

Most relevant for: LGBTQ cancer patients and their healthcare providers.

Little is known about the cancer care experiences of lesbian, gay, bisexual, transgender and queer (LGBTQ) patients. This study looks at recommendations from the LGBTQ community for improving their cancer care. (6/20/19)

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LGBTQ patients recommend improvements for their cancer care

Relevance: Medium-High

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Strength of Science: Medium-High

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Research Timeline: Post Approval

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Study : Prevalence of BRCA founder mutations in Bahamian women

Most relevant for: Bahamanian women

Summary:

The Bahamas has the highest known frequency of BRCA mutations among people diagnosed with breast cancer. This study reviewed whether population-based BRCA testing (testing everyone regardless of family or personal history of cancer) would be an effective approach for finding mutation carriers in the Bahamas. (3/4/19)

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Prevalence of BRCA founder mutations in Bahamian women

Relevance: Low

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Research Timeline: Lab Research

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Article : Promise of a cure for cancer is too good to be true

Most relevant for: People diagnosed with cancer

The Jerusalem Post published an article titled, “A cure for cancer?  Israeli scientists may have found one.” The story profiled a small Israeli company called Accelerated Evolution Biotechnologies that has been working on developing new cancer treatments since 2000. The article relied almost entirely on an interview with the company’s chairperson of the board who made a series of unsubstantiated claims that included that, in a year’s time, the company will offer a complete cure for cancer. (2/12/19)

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Promise of a cure for cancer is too good to be true

Relevance: High

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Quality of Writing: High

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Article : The cost of cancer care and impact of financial hardship on treatment

Most relevant for: Anyone diagnosed with cancer

Several recent studies on the cost of cancer care show the negative effects on cancer patients. In this XRAYS we review a recent article by Kaiser Health News and associated studies about the financial impact of breast cancer treatment and cost of precision medicine. (2/8/19)

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The cost of cancer care and impact of financial hardship on treatment

Relevance: Medium-High

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Quality of Writing: High

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Personal Story : Pamela Munster's story of cancer in the family

Most relevant for: People with an inherited mutation linked to cancer

In her essay in The Washington Post, Dr. Pamela Munster recounts her family's history with cancer associated with a mutation in the BRCA2 gene. She details her father's extraordinary journey with pancreatic cancer, one of the most aggressive and deadly cancers. (11/27/18)

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Pamela Munster's story of cancer in the family

Relevance: High

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Strength of Science: High

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Research Timeline: Post Approval

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Study : Can population-based DNA sequencing find more people at risk for hereditary cancers?

Most relevant for: Women over age 30

It is well documented that many BRCA mutation carriers are missed using current family history-based screening approaches. As a result, experts are beginning to call for population-based BRCA genetic testing—an organized effort to screen all women like we do for breast and cervical cancer.  A recent study looked at whether a population-based genetic testing approach would better identify mutation carriers compared with current practice. (11/17/18)

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Can population-based DNA sequencing find more people at risk for hereditary cancers?

Relevance: High

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Quality of Writing: High

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Article : The importance of racial diversity in clinical trials

Most relevant for: People who are a member of a racial or ethnic minority group

This article by journalists Caroline Chen and Riley Wong looks at racial disparities between participation in clinical trials and the population of people with cancer. (11/6/18)

Este artículo está disponible en español.

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The importance of racial diversity in clinical trials

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