Is asparagus linked to breast cancer metastasis?
Full article: https://www.nature.com/articles/nature25465
A new study published in the journal Nature shows that asparagine, a protein building block that takes its name from asparagus, promotes the spread of breast cancer in mice. The study by cancer experts from Britain, Canada and the U.S. investigated whether limiting the levels of asparagine in mice could reduce tumor metastasis. (3/2/18)
The National Comprehensive Cancer Network (NCCN) creates guidelines for cancer survivorship. Their survivorship guidelines on nutriation and weight management recommend:
- Assessing dietary intake of fruits, vegetables and unrefined grains, as well as red and processed meats, alcohol, and processed foods or beverages with added fats and/or sugars.
- Assess eating habits, including portion size, night grazing, snacking habits, frequency of eating out and use of added fats or sugars to foods or beverages
- All survivors should be encouraged to:
- Make informed choices about food to ensure variety and adequate nutrient intake
- Limit refined sugars
- Eat a diet that is at least 50% plant-based, with the majority of food being vegetables, fruit and whole grains
- Track calorie intake
- Self-monitoring of caloric intake is an effective strategy for weight management
- Minimize alcohol intake
- Limit intake to no more than one drink per day for a woman and two drinks per day for a man
- For patients desiring further recommendations for dietary guidelines, the USDA approximate food plate volumes are:
- Vegetables and fruits should comprise half the volume of food on the plate
- Vegetables: 30% of plate; Fruits 20% of plate
- Whole grains: 30% of plate
- Protein: 20% of plate
- Recommended sources of dietary components:
- Fat: plant sources such as olive or canola oil, avocados, seeds and nuts, and fatty fish
- Carbohydrates: fruits, vegetables, whole grains and legumes
- Protein: poultry, fish, legumes, low-fat dairy foods, and nuts
The American Cancer Society recommendations on nutrition and physical activity include:
- Achieve and maintain a healthy weight throughout life.
- Adopt a physically active lifestyle.
- Consume a healthy diet with an emphasis on plant-based foods
- Limit the amount of processed and red meats:
- Eat at least 2.5 cups of vegetables and fruits a day.
- Chose whole grains instead of refined grain products.
- Drink no more than 1 alcoholic drink per day (women).
Other experts also provide guidelines for nutrition and health, including:
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Questions To Ask Your Health Care Provider
- Can my diet affect my risk for breast cancer metastasis?
- What should I be eating to maximize my health and ability to tolerate treatment?
- Can you provide me with a referral to a nutritionist?
Open Clinical Trials
- NCT02334085 The Health of Women Study (HOW). This study conducted by Dr. Susan Love is recruiting men and women 18 years and older with and without breast cancer to assess factors including diet that influence the risk of breast cancer. Participation is via online survey.
The following clinical trials on diet or nutrition are currently recruiting participants with breast cancer to look at impact on treatment and outcomes:
FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.