Body Mass Index (BMI) may affect how well aspirin use protects against colorectal and ovarian cancer
Full article: https://doi.org/10.1007/s10552-020-01357-2
This study looked at the impact of daily aspirin use for lowering the risk for multiple types of cancers and whether this risk reduction can be modified by cancer risk factors such as obesity, smoking, physical inactivity or a family history of cancer. (3/19/21)
The American Cancer Society (ACS) is a nationwide, community-based voluntary health organization dedicated to eliminating cancer as a major health problem. The organization has released a guideline for the general prevention of cancer.
According to the ACS, the following behaviors can help lower your risk for cancer and boost your odds of living a longer, healthier life:
- Get regular cancer screening tests.
- Regular screening tests can catch some cancers early. Usually, small cancers that have not spread are easier to treat. Talk with your doctor about the recommended tests for breast, colon and prostate cancers.
- Get to and stay at a healthy weight.
- Being overweight or obese is a risk factor for many cancers, including breast, colon, endometrial and pancreatic cancer. You can control your weight through regular exercise and healthy eating.
- Exercise regularly.
- Physical activity has been shown to lower the risk of several types of cancer, including breast, endometrial, prostate and colon cancer. It also reduces the risk of other serious diseases such as diabetes and heart disease.
- Adults should get at least 150 minutes of moderate-intensity activity (equal to a brisk walk) or 75 minutes of vigorous activity (makes your heartbeat and breathing faster and makes you sweat) each week, preferably spread throughout the week.
- Eat a healthy diet.
- Studies show that eating a variety of different vegetables and fruits, whole grains and fish or poultry is linked with a lower risk of developing certain cancers. On the other hand, eating more processed foods and red meat is linked with a higher risk of developing certain cancers. The American Cancer Society recommends:
- Eating at least 2½ cups of vegetables and fruits each day
- Eating less red meat (beef, pork and lamb) and less processed meat (bacon, sausage, luncheon meats and hot dogs)
- Choosing bread, pasta and cereal made from whole grains instead of refined grains, and brown rice instead of white
- Eating fewer sweets
- Avoid tobacco.
- Tobacco use is responsible for nearly 1 of every 5 deaths in the U.S.–about 480,000 premature deaths each year. About 80% of lung cancer deaths and 30% of all cancer deaths are caused by tobacco use.
- Limit alcohol.
- Research has shown that alcohol can increase your risk for certain kinds of cancer, including breast, mouth, throat, voice box, esophagus, liver, colon and rectal cancer. The more alcohol you drink, the higher your risk.
- Men should have no more than 2 drinks a day and women no more than 1. A standard drink of alcohol is defined as 12 ounces of beer, 5 ounces of wine, or 1.5 ounces of 80‐proof distilled spirits.
Questions To Ask Your Health Care Provider
- How can I lower my risk for colorectal cancer, ovarian and other cancers?
- I have a family history of colorectal cancer, ovarian and other cancers; will daily aspirin use benefit me?
Open Clinical Trials
- NCT03480776- Acetylsalicylic acid (aspirin) in Prevention of Ovarian Cancer (STICs and STONEs). While aspirin is not a cancer medication, research suggests that the anti-inflammatory action of aspirin reduces the probability of developing many types of cancer. Inflammation in the ovaries during ovulation is thought to contribute to the development of ovarian cancer; because aspirin is an anti-inflammatory medication, it may help to prevent it.
FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.