Cancer risks of people with inherited PALB2 mutations

https://www.facingourrisk.org/XRAY/PALB2-cancer-risk

Full article: https://doi.org/10.1200/JCO.19.01907

In the largest study of people with inherited PALB2 mutations to date, the gene was linked to increased lifetime risk of breast cancer in women and men, ovarian and pancreatic cancer but not prostate or colorectal cancer. (posted 7/1/21)

Este artículo está disponible en español.

Questions To Ask Your Health Care Provider

I have an inherited PALB2 mutation. What is my risk of cancer?
Given my inherited PALB2 mutation, what preventive options should I consider?
I have been diagnosed with cancer; does my mutation status alter treatment recommendations?
I have a family history of cancer but I have not had genetic testing; should I consider genetic testing?
How do I contact a genetic counselor?

About FORCE

FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.