Joining FORCEs Newsletter

Joining FORCES is the FORCE newsletter with news, views and supportive information for individuals concerned about hereditary breast and ovarian cancer.

Conference On-demand Videos Now Available Online

by Lisa Rezende, Ph.D.

Several important talks from the 2014 Joining FORCEs conference are available online ( Click on the menu option for “2014 conference videos.”

Talk summary: Long-term consequences of menopause.

Risk-reducing salpingo-oophorectomy (RRSO) has been shown to decrease the rate of ovarian cancer and increase lifespan in women with BRCA mutations, but the surgery shifts premenopausal women into immediate menopause. Dr. Susan Domchek (Basser Center for BRCA) and Dr. Neill Epperson (Director, Penn Center for Women’s Behavioral Wellness) presented the latest research on the long-term effects of menopause.

Dr. Domchek’s study of the long-term consequences of surgical menopause after RRSO found that more than 50% of patients had issues with bone loss, stress, hot flashes, decreased libido, attention problems, and sleep loss.

Dr. Epperson discussed the “post-RRSO brain,” detailing the cognitive effects of early menopause on women who undergo RRSO. She noted that:

  • loss of estrogen at a young age affects cognitive function.
  • some women are at risk of depression after menopause.
  • women with early-life adversity are at increased risk of mood and cognitive problems.

Other available video-on-demand titles include:

  • Patient-Powered Research Networks
  • Menopause With and Without Hormones
  • Pancreatic Cancer Detection, Prevention, and Treatment
  • Update on Targeted Therapies
  • Complementary and Integrative Medicine for Symptom Management
  • Putting it All Together to Make Decisions
  • What's New in HBOC Research?


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