No one should face hereditary cancer alone.

Thinking about cancer or dealing with cancer risk can be scary or overwhelming, but we believe that receiving information and resources is comforting, empowering, and lifesaving.

Hereditary Cancer Info > Risk Management > Breast Cancer Chemoprevention


BRCA & HBOC
Toggle Menu

Breast Cancer Chemoprevention

Learn about the steps that people at high risk for cancer can take to manage their risk and protect their health.

Aromatase Inhibitors

Aromatase inhibitors are medications that block the production of estrogen by fat and adrenal cells in postmenopausal women. Common aromatase inhibitors include anastrozole (Arimidex), letrozole (Femara), and exemestane (Aromasin).

Unlike SERMs, aromatase inhibitors do not improve bone density. In fact, they may actually accelerate bone loss in postmenopausal women. However, aromatase inhibitors appear to cause fewer side effects and do not appear to have the risk of blood clots or endometrial cancer as seen with tamoxifen.

 No trials have been conducted on the use of aromatase inhibitors for the prevention of breast cancer in women with a BRCA mutation.

Updated 03/31/2019

FORCE:Facing Our Risk of Cancer Empowered