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Genes Associated with Hereditary Cancers

Learn about genes and cancer, signs of hereditary cancer, genetic counseling, types of genetic tests and what results mean for you and your family.


BARD1 (BRCA1 Associated Ring Domain 1) is a gene that works with BRCA1 to repair damaged DNA.  Although “BARD1” includes a reference to BRCA1, the two genes are different; people with BARD1 mutations do not necessarily have BRCA1 mutations.

Some studies have shown that inheriting a mutation in BARD1 increases a woman’s risk for breast cancer. Ongoing research is exploring the extent of that risk and whether or not a BARD1 mutation increases a person’s risk for other types of cancers.

No national guidelines exist for managing cancer risk in people who inherit a mutation in BARD1. We recommend consulting with a genetics expert who can assess your personal and family history of cancer, and can help you to determine the best risk-management plan.

Updated 07/28/2017

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