Prospective Registry Of MultiPlex Testing (PROMPT)

Clinicaltrials.gov identifier:
NCT02665195 (https://clinicaltrials.gov/ct2/show/NCT02665195)

The study is being conducted by researchers at University of Pennsylvania, Dana-Farber Cancer Center, Memorial Sloan Kettering and Mayo Clinic. You can contact the study team via email or by visiting the study website. You do not have to be a patient at the lead institutions to enroll.

About the Study

PROMPT is an online research registry for people who have had genetic panel testing (also known as multiplex testing) — a newer form of genetic testing that looks for mutations in several different genes at once. All genes on the panels have been linked to an increased risk of cancer, but some risks are better known than others.

The goal of the PROMPT Registry is to follow people with mutations or variants in genes on these panels, so that patients, physicians, and researchers can more clearly understand these lesser-known risks. For more information visit the PROMPT Study website.

What the Study Entails

People can enroll in PROMPT by completing an secure, online questionnaire about their personal and family medical history. You do not have to travel or be a patient at the institution in order to enroll.

Study Lead Investigators

Susan Domchek, MD: Basser Research Center for BRCA. Contact email: [email protected].

Mark Robson, MD: Memorial Sloan Kettering Cancer Center. Contact email: [email protected].

This Study is Open To:

Adults can enroll in PROMPT if they have had any of the following:

have had genetic testing for multiple genes (panel testing) and have tested positive for a mutation in a gene associated with cancer risk
have had genetic testing for multiple genes (panel testing) and have a variant of uncertain significance (VUS) in one of the genes associated with cancer risk
member of a family where one of the members had panel testing and tested positive for a mutation or a VUS in one of the genes

This Study is Not Open To:

About FORCE

FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.

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