Registry to Discover New Treatments and Developmental Processes of Colorectal and Endometrial Cancer in Patients with Hereditary Cancer identifier:
NCT06096688 (

Surveys, Registries, Interviews
Study to collect and save data, cancer samples, and cancer family health histories from people who screen for colorectal endometrial cancer

Study Contact Information:

For additional information, please contact:  

Principal Investigator: Steven M Lipkin, MD, PhD at 212-746-4014 or [email protected]

Melissa K Frey, MD, MS at 646-697-6621 or [email protected]

About the Study

This research registry will collect and save data, cancer samples and family health history information to discover new ways cancer develops. It will look to find new genes that could be used for treatments and preventing cancer for people with hereditary cancer.

This research will explore the features of samples including tumors in the stomach, intestines, and the endometrium. The study will compare these features between people with hereditary cancers and others. It will also collect blood and assess makers including DNA and RNA.

The study will do experiments in test tubes and animals to find the pathway that cancer develops and test the effects of drugs.

What the Study Involves

People will provide samples from their stomach, intestines, and/or uterus during regular procedures such as endoscopy, ultrasound, biopsy, and surgery. They will also give blood and/or saliva along with information about their treatment and the results.

Study Sites

New York
New York Presbyterian Hospital (NYPH) and Weill Cornell Medicine (WCM)

Lead Researchers: 

Steven M Lipkin, MD, PhD
Melissa K Frey, MD, MS

This Study is Open To:

People, 18 years of age or older, who meet the following criteria:

This Study is Not Open To:

People under the age of 18 and do not meet the criteria listed above


FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.