TAPUR Study: Testing FDA Approved Drugs Targeting Tumor Biomarkers in People with Advanced Stage Cancer identifier:
NCT02693535 (

Cancer treatment study for people with advanced solid tumors

Study Contact Information:

Pam Mangat by email at [email protected] or at the study website

About the Study

The TAPUR Study is looking at the safety and efficacy of FDA-approved, targeted drugs to treat advanced cancers with certain tumor biomarkers. If interested, talk to your doctor about biomarker testing and visit to find a participating center near you. Check here for the list of tumor mutations, markers and cancer types that are part of study eligibility. 

What the Study Involves

The TAPUR Study is looking at many different cancer types, biomarkers, and drugs all in the same clinical trial. The study has broad eligibility, collects the minimum necessary data, and allows for flexibility in visits, treatment decisions, and care decisions to better benefit the participants. Each cancer type and treatment type follows different treatment timelines, so speak with the study contact if you have questions about what would be required of you if you are eligible and decide to join the study.

More about the Study

The TAPUR Study is a phase II, nonrandomized clinical trial. Phase II means that the study looks at efficacy and side effects of the anticancer study treatments. Nonrandomized means that participants are not randomly divided into treatment groups.

Study Locations:


University of Alabama at Birmingham Comprehensive Cancer Center- Birmingham
Contact: Misty Lowery; 205-644-2573; [email protected]


Cancer Treatment Centers of America- Phoenix
Contact: Russell Fernandez; 623-207-3126; [email protected]


Kaiser Permanente- Oakland Medical Center- Oakland
Kaiser Permanente- Roseville Medical Center- Roseville
Kaiser Permanente- Sacramento Medical Center- Sacramento
Kaiser Permanente- South San Francisco Medical Center- San Francisco
Kaiser Permanente- San Francisco Medical Center- San Francisco
Kaiser Permanente- San Jose Medical Center- San Jose
Kaiser Permanente- San Leandro Medical Center- San Leandro
Kaiser Permanente- Santa Clara Medical Center- Santa Clara
Kaiser Permanente- Vallejo Medical Center- Vallejo
Kaiser Permanente- Walnut Creek Medical Center- Walnut Creek
Contact: Desiree Goldstein; [email protected]

California Pacific Medical Center Research Institute- San Francisco
Sutter Sacramento- Sacramento
Sutter Auburn- Auburn
Sutter Alta Bates- Berkeley
Sutter Roseville- Roseville
Sutter Palo Alto Medical Foundation- Palo Alto
Sutter Palo Alto Medical Foundation- Santa Cruz
Sutter Palo Alto Medical Foundation- Fremont
Sutter Palo Alto Medical Foundation- Sunnyvale
Contact: Juliana Van Cleve; 415-600-1654; [email protected]

The Angeles Clinic and Research Institute, A Cedars-Sinai Affiliate- Los Angeles
Contact: Saba Mukarram; 310-231-2181; [email protected]


Hartford Healthcare System

Saint Vincent’s Medical Center- Bridgeport
Hartford Hospital- Hartford
Midstate Medical Center- Midstate
The Hospital of Central Connecticut- New Britain
William W. Backus Hospital- Norwich
Charlotte Hungerford- Torrington
Windham Hospital- Willimantic
Contact: Melanie Manning; 860-972-5029; [email protected]


University of Florida
Contact: Nghi Lam; 352-265-5329; [email protected]

University of Miami Sylvester Comprehensive Cancer Center
Contact: Carolina Troche; 305-243-1481; [email protected]

Fort Lauderdale
Holy Cross Hospital
Contact: [email protected]

Fort Myers
Florida Cancer Specialists South/ Sarah Cannon Research Institute
Contact: Kristen Borresen; 717-216-1143x13038; [email protected]  

Saint Petersburg
Florida Cancer Specialists North/ Sarah Cannon Research Institute
Contact: Kristen Borresen; 717-216-1143x13038; [email protected]  

Florida Cancer Specialists Panhandle/ Sarah Cannon Research Institute
Contact: Kristen Borresen; 717-216-1143x13038; [email protected]  

West Palm Beach
Florida Cancer Specialists East/ Sarah Cannon Research Institute
Contact: Kristen Borresen; 717-216-1143x13038; [email protected]  


Cancer Treatment Centers of America, Atlanta
Contact: Mittie Mitchell; 770-400-7194; [email protected]

Emory University Winship Cancer Institute
Contact: Suzanne Scott; 404-778-4083; [email protected]

Lewis Cancer and Research Pavilion
Summit Cancer Care
Gynecologic Oncology and Surgical Specialists at the Lewis Cancer and Research Pavilion
Lewis Cancer and Research Pavilion at the Melanoma, Skin Cancer, and Sarcoma Institute
Contact: Stephanie Smith; 912-819-5723; [email protected]


The Queen’s Medical Center (The University of Texas MD Anderson Cancer Center)
Contact: Amanda Eckert; 713-745-8074; [email protected]


Cancer Treatment Centers of America, Chicago
Contact: Rosielyn Sheridan; 847-872-4966; [email protected]


Community Health Network (The University of Texas MD Anderson Cancer Center)
Contact: Amanda Eckert; 713-745-8074; [email protected]


Jackson Laboratory- Main Cancer Genomics Initiative
Harold Alfond Center for Cancer Care
Contact: Sandra Neptune; 207-626-4811; [email protected]

Jackson Laboratory- Maine Cancer Genomics Initiative
Contact: Petra Helbig; 207- 664- 4659; [email protected]

Waldo County General Hospital- Belfast
SMHC Cancer Care and Blood Disorders- Biddeford
MaineHealth Cancer Care- Brunswick
Stephens Memorial Hospital- Norway
Penobscot Bay Medical Center- Rockport
SMHC Cancer Care and Blood Disorders, Sandford- Sandford
Maine Children’s Cancer Program- Scarborough
Maine Medical Partner’s Women’s Health- Scarborough
MaineHealth Cancer Care, South Portland- South Portland
Contact: Jen Dalton; 207- 294- 8291; [email protected]

Northern Light Cancer Center- Brewer
Raish Peavy Haskell Children’s Cancer and Treatment Center- Brewer
Contact: Carla Mancini; 207-973-5581; [email protected]

New England Cancer Specialist- Kennebunk
New England Cancer Specialist- Scarborough
New England Cancer Specialist- Topsham
Contact: Patricia C. Collins; 207-303-3422; [email protected]

York Hospital Oncology and Infusion Care in Kittery- Kittery
York Hospital Oncology and Infusion Care in Wells- Wells
York Hospital Oncology and Infusion Care in York- York
Contact: Branda Kilberd; 207-361-6115; [email protected]


University of Michigan- Ann Arbor
Contact: Cancer AnswerLine Nurses; 800-865-1125; [email protected]

Cancer Research Consortium of West Michigan- Grand Rapids
Ascension Borgess Cancer Center- Kalamazoo
Contact: Connie Szczepanek; 616-391-1230; [email protected]
PI: Kathleen J. Yost, MD

Trinity Health Ann Arbor Hospital
Trinity Health Medical Center – Brighton
Trinity Health Medical Center – Canton
Chelsea Hospital – Chelsea
Trinity Health Oakland Hospital – Pontiac
Ascension St. John Hospital- Detroit
Van Elslander Cancer Center – Grosse Pointe Woods
Doctors Park – East China
Macomb Medical Campus – Macomb Township
Macomb Professional Building – Warren
Michigan Breast Specialists – Warren
Advanced Breast Care Center PLLC – Warren
Genesys Hurley Cancer Institute – Grand Blanc
Genesee Cancer and Blood Disease Treatment Center – Grand Blanc
Genesee Hematology Oncology, PC – Grand Blanc
Sparrow Hospital- Lansing
Ascension St. Mary’s Hospital- Saginaw
Oncology Hematology Associates of Saginaw Valley PC – Saginaw
Ascension Saint Joseph Hospital – Tawas City
Saint Mary’s Oncology/Hematology Associates of West Branch – West Branch
Trinity Health Livonia Hospital – Livonia
St. John Macomb Oakland Hospital- Warren
Contact: 734-712-7251; [email protected]


University of Nebraska Medical Center- Omaha
Nebraska Medicine Bellevue Medical Center- Bellevue
Village Pointe (University of Nebraska Medical Center)- Omaha
Contact: Tannette Welsh; 402-552-3594; [email protected]

New Hampshire

NH Oncology/Hematology- Concord
Solinsky Center for Cancer Care- Manchester
Contact: Ali Fleury; 603- 314- 6888; [email protected]

New England Cancer Specialists, Portsmouth
Contact: Patricia Collins; 207-303-3422; [email protected]

New Mexico

Lovelace Medical Center
Contact: Leslie Byatt; 505-925-0366; [email protected]

Presbyterian Kaseman Hospital
Contact: Monique Robertson; 505-559-6100; [email protected]

The University of New Mexico Comprehensive Cancer Center
Contact: Kawryn Gustafson; 505-925-0380; [email protected]

Las Cruces
Memorial Medical Center
Contact: Kim Hoffman; 575-556-6545; [email protected]

Rio Rancho
Presbyterian Rust Medical Center
Contact: Andrea Yost; 505-253-7878; [email protected]

New York

Northwell Health Monter Cancer Center- Lake Success
Manhattan Eye, Ear, and Throat Hospital- New York
Cohen Children’s Medical Center- New Hyde Park
Phelps Hospital- Sleepy Hollow
Contact: Mary Agnes Templeton; 516-734-8979; [email protected]

Herbert Irving Comprehensive Cancer Center- New York
Contact: Kim Roman; 212-342-3970; [email protected]  

North Carolina

Chapel Hill
Lineberger Comprehensive Cancer Center
Contact: Emmie Cole; 919-966-4432; [email protected]

Atrium Health’s Levine Cancer Institute
Contact: Kelly Bumgarner; 704-403-2520; [email protected]

North Dakota

Sanford Health
Contact: Kassandra Remmel; 701-234-7515; [email protected]

Sanford Health
Contact: Ellen Nelson; 701-234-7514; [email protected]


University of Cincinnati Medical Center - Cincinnati
West Chester Hospital- West Chester
Contact: Kayla Webb; 513-584-0599; [email protected]

Kettering Health- Kettering
Contact: Terri vanZant-Marvin; [email protected]


Providence Health and Services- Portland
Contact: Isa Ngirailemesang; 971-358-2056; [email protected]


Lehigh Valley Health Network- Allentown
Lehigh Valley Hospital, Muhlenberg- Bethlehem
Lehigh Valley Hospital, Hazleton- Hazelton
Pocono Medical Center- East Stroudsburg
Contact: 734-712-7251; [email protected]

Fox Chase Cancer Center- Philadelphia
Contact: Joan Aresco; 734-712-3304; [email protected]

South Carolina

Levine Cancer Institute- Rock Hill
Contact: Kelly Bumgarner; 704-403-2520; [email protected]

SC Cancer Specialists at St. Joseph’s Candler Bluffton- Bluffton
St. Joseph’s Candler Bluffton- Bluffton
Summit Cancer Care at St. Joseph’s/Candler Bluffton- Bluffton
South Carolina Cancer Specialists- Hilton Head Island
Contact: Stephanie Smith; 912-819-5723; [email protected]

South Dakota

Sanford Health- Sioux Falls
Contact: Michaela Melberg; 602-312-6229; [email protected]


Tennessee Oncology, Nashville/ Sarah Cannon Research Institute
Contact: Ethan Trull; 615-329-7274; [email protected]


The University of Texas MD Anderson Cancer Center
Contact: Amanda Eckert, MPH; 713-745-8074; [email protected]


Dixie Regional Medical Center, River Road Campus- St. George
Dixie Regional Medical Center, 400 East Campus- St. George
Cedar City Hospital, SW Cancer Clinic, Sandra Maxwell Center- Cedar City
Contact: Rachel Pernick; 435-251-4743; [email protected]

Intermountain Precision Genomics Cancer Research Clinic- Salt Lake City
Contact: Tracy Taylor; 801-507-3953; [email protected]


Inova Schar Cancer Institute- Fairfax
Inova Fairfax Hospital- Fairfax
Inova Fair Oaks Hospital- Fairfax
IMG Oncology, Oncology GYN- Annandale
Contact: Roxana Comfort; 571-472-0624; [email protected]


Swedish Cancer Institute- Seattle
Swedish Cancer Institute, Ballard/Seattle- Seattle
Swedish Cancer Institute, Edmonds- Edmonds
Swedish Cancer Institute, First Hill/Seattle- Seattle
Swedish Cancer Institute, Gynecologic Oncology and Pelvic Surgery Clinic, First Hill- Seattle
Swedish Cancer Institute, Gynecologic Oncology and Pelvic Surgery Clinic, Issaquah- Issaquah
Swedish Cancer Institute, Issaquah- Issaquah
The Ben and Catherine Ivy Center for Advanced Brain Tumor- Seattle
Contact: Kimberly Reeves; 206-386-2227; [email protected]


Aurora Cancer Care- Burlington
Aurora Health Care, Germantown Health Center- GermantowAurora Cancer Care- Grafton
Aurora BayCare Medical Center- Green BaAurora Cancer Care, Kenosha South- Kenosha
Aurora Bay Area Medical Center- Marinetta
Aurora Cancer Care- Milwaukee
Aurora St. Luke’s Medical Center- Milwaukee
Aurora Sinai Medical Center- Milwaukee
Aurora West Allis Medical Center- Milwaukee
Vince Lombardi Cancer Clinic- Oshkosh
Aurora Cancer Care- Racine
Vince Lombardi Cancer Center- Sheboygan
Aurora Medical Center- Summit
Vince Lombardi Cancer Clinic- Two Rivers
Aurora Cancer Center, Milwaukee West- Wauwatosa
Contact: Michelle Toutloff; 920-456-7880; [email protected]

Lead Researchers/Study PIs and Affiliation

Richard Schilsky, MD, FACP, FSCT, FASCO [email protected]

This Study is Open To:

To qualify for this study, you must have the following:

  1. Advanced cancer including: solid tumors (ex.: carcinomas, sarcomas), with a biomarker that can be targeted with a study drug. Your oncologist can help determine if this applies to you. You can view the list of biomarkers and cancer types here
  2. You are no longer benefitting from standard treatment or there is no standard treatment option/s available.
  3. You are healthy enough to participate.
  4. You are at least 12 years of age or older.*
  5. You are not currently pregnant and do not plan to become pregnant soon.
  6. The cancer is no longer responding to standard anti-cancer treatment or no standard treatment is available.
  7. You have had a genomic or molecular test performed on your tumor.
  8. You are out of bed and active at least half of each day.

* Some restrictions apply. Not all TAPUR Study therapies are available for participants under 18 years of age. Contact a participating TAPUR Study clinical site or the TAPUR Study team using the “Contact Us” form below to learn about the eligibility age for a specific study drug.

The dose, frequency, and duration of treatment will vary depending on the drug that the participant takes. Any additional biopsies, appointments, labs, etc. that are not required for screening will also vary depending on the drug that is being taken. Each drug has its own eligibility criteria.

This Study is Not Open To:

  1. You do not have an advanced cancer.
  2. You are on a current treatment that is beneficial to you.
  3. You are pregnant or plan to become pregnant soon.
  4. Your cancer is currently responding to standard anti-cancer treatment or there is standard treatment available to you. 
  5. You have not had a genomic or molecular test performed on your tumor.
  6. You are bed-ridden or not active at least half of each day. 


FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.