A New Risk Measurement Tool for Those at High Risk for Ovarian Cancer

About the Study

This study is using a new type of genetic test to measure ovarian cancer risk in women who have inherited gene mutations that increase their risk for ovarian cancer or women who have an ovarian cyst or a growth in the area of the ovaries or fallopian tubes (adnexal mass). This genetic test looks at seven genetic markers and then provides a score on a scale from 0 to 20 that will tell you your risk for ovarian cancer. The higher the score, the higher your risk.

What the Study Involves

There are three groups that this study is recruiting. Each group will undergo a blood draw to use the risk measurement tool (OVAnex) so that each participant will have a risk score on a scale from 0 to 20.

1. Group A is for women with an ovarian cyst or other benign ovarian who have symptoms from the mass
2. Group B is for women who have an ovarian cyst or other benign mass who have no symptoms from the mass
3. Group C is for women with an inherited gene mutation that puts them at high risk for ovarian cancer

Participants will be enrolled in the study for a total of 12 months.

Study Locations

Arizona

• Chandler
  Women's Health Arizona    
  Contact: Dr. Monte Swarup by email    

Georgia

• Columbus
  MidTown OBGYN
  Contact: Dr. Serena Tidwell by email
  Contact: Rebecca Watkins by email      

Minnesota

• Eden Prairie
  Premier OBGYN of Minnesota    
  Contact: Dr. Katie Toft by email

New York

• New Hyde Park
  Square Care Health    
  Contact: Dr. Frank Dolisi by email

Ohio

• Cincinnati
  Seven Hills Clinical Research Group
  Contact: Gerard Reilly, MD by email

Pennsylvania

• Lancaster
  May Grant OB/GYN
  Contact: Dr. Kent Meldrum by email

Texas

• Austin
  Hill Country OBGYN Associates
  Contact: Dr. Ana Eduardo by email

• Women over the age of 18 with an ovarian cyst or other mass that isn't cancer, or in follow-up due to the presence of an inherited mutation in BRCA1, BRCA2 or other gene linked to ovarian cancer risk.
• The patient reviewed, understood, and provided the study team with written informed consent to allow blood specimen to be used for research and release of medical information.

*Contact your doctor, the study coordinators or review the clinicaltrials.gov listing for a complete list of inclusion criteria.

• Participant is less than 18 years of age
• Participant is not being treated in the U.S.

*Contact your doctor, the study coordinators or review the clinicaltrials.gov listing for a complete list of inclusion criteria.