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Our Featured Research Page lists cancer prevention, treatment and quality of life studies enrolling people with or at high risk for hereditary cancers. You can do a quick search to filter our featured studies by cancer type, study type or key word, or a more in-depth search through clinicaltrials.gov.

Search Results: Prevention, Detection & Risk (5 results)

1 through 5 of 5
Men at High Genetic Risk for Prostate Cancer

Prevention
Prostate screening with MRI for men with Lynch syndrome or a BRCA1/2, ATM, BRIP1, CHEK2, PALB2, RAD51C/D, TP53, HOXB13, FANCA or NBN mutation

Men at High Genetic Risk for Prostate Cancer

The National Cancer Institute has opened a clinical trial for prostate cancer screening in men who are at high risk for prostate cancer due to an inherited mutation. This is trial is for men without prostate cancer, ages 30 to 75, who have tested positive for Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) or BRCA1, BRCA2, HOXB13, NBN, TP53, CHEK2, PALB2, RAD51C RAD51D, BRIP1, FANCA or ATM mutation. The trial involves screening MRI of the prostate every two years and biopsy of the prostate if the MRI is abnormal. There is no cost for travel or study-related tests.

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Atorvastatin ± Aspirin for Colorectal Cancer Prevention for People with Lynch Syndrome

Prevention

Atorvastatin ± Aspirin for Colorectal Cancer Prevention for People with Lynch Syndrome

This study will look at how well atorvastatin (a cholesterol lowering agent) works with or without aspirin in preventing colorectal cancer in people with Lynch syndrome. Atorvastatin may lower the risk of developing cancers in the colon and rectum. Aspirin may reduce the risk of colon polyps and colon cancers. Giving atorvastatin and aspirin may work better at reducing the risk of colorectal cancer (CRC) in high-risk individuals with Lynch syndrome.

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Blood Markers of Early Pancreas Cancer

Prevention
Screening for people with family history of pancreas cancer or an inherited mutation linked to pancreatic cancer risk.

Blood Markers of Early Pancreas Cancer

The purpose of this study is to try to find markers of early pancreatic cancer for screening for individuals at higher-than-average risk, expedite the diagnosis in individuals with symptoms, and substantially improve an individual's chance of surviving the disease.

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Pancreatic Cancer Screening Study for High Risk People

Prevention

A Pancreatic Cancer Screening Study for High Risk Individuals

The purpose of this study is to screen and detect pancreatic cancer and precancer in people with either a strong family history of pancreatic cancer, or an inherited mutation associated with pancreatic cancer risk.

Magnetic Resonance Imaging (MRI) will be used to screen for early stage pancreatic cancer. Participants will also be asked to donate a blood sample at specific intervals for the creation of a blood bank necessary for the development of a blood-based screening test for pancreatic cancer. 

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Pancreatic Cancer Early Detection

Prevention

Pancreatic Cancer Early Detection Program

This is a study looking at esophageal ultrasound and Magnetic Resonance Imaging (MRI) as a screening for pancreatic cancer in high risk individuals. 

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Additional Results on Clinicaltrials.gov Prevention, Detection & Risk + lynch syndrome
4 results
Clinical Trial Official Title
NCT05257057 Frequency of Endometrial Cancer Precursors Associated With Lynch Syndrome
NCT05129605 Prostate Cancer Genetic Risk Evaluation and Screening Study
NCT03568630 Blood Markers of Early Pancreas Cancer
NCT02206360 Pancreatic Cancer Early Detection Program

Research Search Tool Sponsored By:

Merck & Co., Inc.
Mike & Patti Hennessy Foundation