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Search Results: Prevention, Detection & Risk + Colorectal Cancer (7 results)

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Testing A Combination Of Vaccines For Cancer Prevention In Lynch Syndrome

Prevention
Testing a combination of vaccines for cancer prevention in Lynch syndrome

Lynch Syndrome Vaccine Study

This study is being done to assess the safety and effectiveness of a series of vaccines (Tri-Ad5), together with another drug (N-803) that magnifies the body’s response to vaccines, to see if there is an effect on the risk of developing colon and other cancers in LS patients.

Clinicaltrials.gov identifier: NCT05419011
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Testing the Safety And Action of the Investigational Drug REC-4881 in People With Familial Adenomatous Polyposis (FAP)

Prevention
Prevention study for people with an APC mutation and FAP who have had colectomy surgery

Testing the Safety And Action of the Investigational Drug REC-4881 in People With Familial Adenomatous Polyposis (FAP) (TUPELO Study)

This study is looking at how safe and effective the research drug REC-4881 is for treating polyps in people with Familial Adenomatous Polyposis (FAP). Participants will receive the oral drug REC-4881. A participant's dose will depend on when they join the study. 

Clinicaltrials.gov identifier: NCT05552755
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Early Detection of Colorectal Cancer for People with Lynch Syndrome

Prevention
People with Lynch Syndrome at risk for colon cancer

Collecting Blood and Stool Samples to Detect Colorectal Cancer or Precancerous Polyps in Lynch Syndrome Patients, CORAL Study

This study will colect blood and stool samples to detect colorectal cancer or precancerous polyps in people with Lynch syndrome and those diagnosed with early onset colorectal cancer, diagnosed younger than 50 years old. 

Clinicaltrials.gov identifier: NCT05410977
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My Best GI Eating Study

Prevention
Diet and weight loss study for people who are overweight and at increased risk of colorectal cancer

My Best GI Eating Study

This study will test three different diets in people who are overweight and who have an increased risk of colorectal cancer. The study will look at whether these diets improve eating and possibly lead to weight loss. 

 

Clinicaltrials.gov identifier: NCT05396846
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Testing the Drug Obeticholic Acid for Familial Adenomatous Polyposis

Prevention
Prevention study for people with an APC mutation and FAP or AFAP who have polyps in remaining tissue after colectomy surgery

Testing the Drug Obeticholic Acid for Familial Adenomatous Polyposis

This study is looking at whether obeticholic acid (OCA) is safe and has a beneficial effect on the number of polyps in the small bowel and colon in people with familial adenomatous polyposis (FAP). OCA is a drug similar to a bile acid the body's liver makes. Researchers believe OCA may help keeping cancer from developing. OCA is already FDA approved to treat a type of liver disease. There have been studies showing that OCA decreases inflammation and fibrosis. However, it is not yet known whether OCA works on reducing the number of polyps in patients with FAP.

Clinicaltrials.gov identifier: NCT05223036
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Studying the Use of Naproxen and Aspirin for Cancer Prevention in People with Lynch Syndrome

Prevention
Prevention study for people with Lynch syndrome

A Study Comparing Two Anti-inflammatory Medications Naproxen or Aspirin for Cancer Prevention in Lynch Syndrome

The trial is enrolling people with Lynch syndrome. On average, the length of this study will last one year from the start of enrollment to completion. The study will measure  the effect of naproxen or aspirin on the immune cells in the gastrointestinal tract of people with Lynch syndrome. The trial will also evaluate any symptoms from the medications and any other changes of the colon and rectum.

Clinicaltrials.gov identifier: NCT05411718
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Helping People With a Genetic Mutation in BRCA1, BRCA2 or Lynch Syndrome Talk to Their Family Members About Their Risk for Cancer and Find the Best Way to Get Family Members Tested

Prevention
People with a genetic mutation in BRCA1, BRCA2 or Lynch syndrome who have relatives who have not been tested

IGNITE-TX - Identifying Individuals for Genetic Testing for Familial Cancer

The IGNITE-TX study is all about helping people with a genetic mutation in BRCA1, BRCA2 or Lynch syndrome talk to their family members about their risk for cancer and find the best way to get family members tested.

Clinicaltrials.gov identifier: NCT05677048
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Additional Results on Clinicaltrials.gov Prevention, Detection & Risk + Colorectal Cancer
33 results
Clinical Trial Official Title
NCT06294873 Stool Sample Collection Study
NCT06620627 Prospective Collection of Samples to Enable the Development of Natera Screening Assay for Early Cancer Detection
NCT05929820 Impact of Protect Your Colon™ on CRC Screening
NCT04748380 Shared Decision-making and Colorectal Cancer Screening
NCT06342440 Early Detection of Advanced Adenomas and Colorectal Cancer
NCT03789162 Blood and Stool Sample Collection in Subjects with a Diagnosis of Colorectal Cancer or Colorectal Lesion: Act Fast
NCT06708429 Lynch Syndrome X-Talk of Enteral Mucosa With Immune System
NCT05785780 Aim 3, Optimizing CRC Screening in Patients With Diabetes in Safety-net Primary Care Settings
NCT06059963 A Prospective, Multi-center, Observational Study for Signal-C Test Evaluation
NCT06612281 Evaluation of Gixam's Performance in a FIT Negative Population
NCT06052202 A Smartphone-Based Intervention to Improve Colorectal Cancer Screening in African American Men
NCT05765214 Impact of Colorectal Cancer and Nutrition Education Program Among Minority Patients With Type 2 Diabetes
NCT04313114 The PRIME-CRC Trial to Promote CRC Screening in Rural Communities
NCT05396846 My Best GI Eating Study
NCT04825834 DNA Evaluation of Fragments for Early Interception - Lung Cancer Training Study (DELFI-L101 Study)
NCT06117241 Reducing Metabolic Dysregulation in Dyads
NCT06542835 Community Partnership for Telehealth Solutions to Counter Misinformation and Achieve Equity
NCT04331535 The Genomic Medicine at VA Study
NCT05447923 Addressing Disparities in Colorectal Cancer Screening in Black and Underserved Phoenix Communities
NCT05732623 Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer
NCT06682650 Implementation of a ColoRectal Cancer Screening Tool in US Primary Care Practices - Usual Quality Improvement (10 Clinics) vs Normalization Process Theory-Participatory Learning in Action (10 Clinics)
NCT04792684 Collection of Samples USOPTIVAL Study
NCT06173375 Head to Head Mailed Cologuard to Mailed FIT
NCT00843375 Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas
NCT06444542 Understanding Patient Preference on Colorectal Cancer Screening Options-PSU
NCT06191185 IMProving Adherence to Colonoscopy Through Teams and Technology
NCT05694559 Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics
NCT04973007 Comparison of Contrast Agents in Liver MR for the Detection of Hepatic Metastases
NCT05793593 A Study of Using Social Networks to Encourage Three Peers to Complete Screening for Colorectal Cancer
NCT01060371 Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias
NCT05524428 Eliminating Barriers to Colorectal Cancer Screening Using Rapid Cycle Testing: A Pilot Study
NCT05410977 Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients, CORAL Study
NCT05612347 Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

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