Skip to main content
About Us
|
Español
Open Search Box
Search by Keyword
Submit Search
Main Menu
Open Search Box
Search by Keyword
Submit Search
DONATE
Hereditary Cancer
& Genetic
Testing
Risk Management & Treatment
Research
Support &
Public Policy
Resources
Search by Keyword
Submit Search
Hereditary Cancer
& Genetic
Testing
Risk Management & Treatment
Research
Support &
Public Policy
Resources
Hereditary Cancer & Genetic Testing
Go back to previous menu.
Hereditary Cancers
Genetic Testing
Hereditary Cancers
Go back to previous menu.
Hereditary Cancer Basics
Learn how gene mutations can lead to cancer, what types of cancer may be hereditary and how parents can pass inherited mutations to their children.
Cancer Risks by Gene
Read about different genes that are linked to hereditary cancer and the risks associated with inherited mutations in these genes.
Genetic Testing
Go back to previous menu.
How Do I Get Genetic Testing?
Learn more about genetic testing and how to take the next steps to get tested.
After Testing Now What
Learn how to make medical decisions and assemble your health care team once you receive your genetic test results.
Sharing Results with Family
Explore tips to help you communicate your family medical history or genetic test results with relatives.
Risk Management & Treatment
Go back to previous menu.
Risk Management & Treatment by Mutation & Cancer
Reconstruction or Going Flat
Menopause, Well-Being & Survivorship
Fertility & Family Planning
Risk Management & Treatment by Mutation & Cancer
Go back to previous menu.
Risk Management & Treatment by Mutation
Review updated information on cancer risks and national guidelines on screening, prevention and treatment options listed by gene.
Risk Management & Treatment by Cancer
Review updated information on screening, prevention and treatment options listed by cancer site.
Risk Management & Treatment by Treatment Type
Review information on prevention and treatment options listed by treatment type
Risk Management for Transgender People
Review guidelines on prevention and screening options for transgender people with inherited mutations.
Reconstruction or Going Flat
Go back to previous menu.
Types of Reconstruction
Understand the types of breast reconstruction.
Going Flat
Learn more about the option of going flat.
Preparation and Recovery
Prepare for surgery and recovery.
Photo and Video Gallery
See images & videos of individuals after mastectomy and reconstruction.
Menopause, Well-Being & Survivorship
Go back to previous menu.
Menopause
Learn about ways to manage the effects of menopause with and without hormones.
Well-Being & Survivorship
Learn how to manage the short- and long-term effects of cancer risk, diagnosis, prevention and treatment.
Research
Go back to previous menu.
Enroll in Research
Research Advocacy
Enroll in Research
Go back to previous menu.
Search and Enroll
Ready to enroll? Our tools will help match you to hereditary cancer detection, prevention and treatment studies.
How to Find Studies
These tips and resources will help you locate clinical trials and studies enrolling people like you.
Why Enroll in Research?
Learn why you should consider enrolling in a research study and your rights and protections as a research participant.
Research Advocacy
Go back to previous menu.
Help Shape Research
FORCE trains patients with no science background to use their personal experiences to help guide hereditary cancer research.
Resources for Researchers
These tips and resources were developed by research advocates to help investigators work with patient stakeholders to strengthen and accelerate their research.
Support & Public Policy
Go back to previous menu.
Support
Paying for Care
Public Policy & Advocacy
Support
Go back to previous menu.
Personalized Guidance
Match with a Peer Navigator volunteer with similar experience as you for confidential 1:1 phone/email support and a free resource guide.
Support Meetings & Partner Events
Review our calendar to connect with others and obtain support and vital resources.
Private Facebook Group
Connect with others over social media who are affected by hereditary cancer.
Message Boards
Register for our forum where you can discuss topics online 24/7 with other people who face similar hereditary cancer concerns.
Helpline
Ask questions and receive nonjudgmental support and resources in English and Spanish. A Genetic Counselor helpline is also available.
Decision Checklists and Tip Sheets
Use our interactive tool to create personalized lists of questions to ask your doctors and tips to prepare for surgeries and procedures.
Find Healthcare Providers
Locate services or medical experts knowledgeable in cancer genetics, including genetic counselors, oncologists, surgeons, fertility experts and more.
Volunteer
Get involved by supporting others, advocating for laws and research that benefit our community and raising awareness of hereditary cancer on social media.
Paying for Care
Go back to previous menu.
Insurance & Reimbursement
Learn about health insurance coverage and reimbursement for healthcare services. Get tips on insurance appeals and customizable sample appeal letters.
Financial Assistance
Find national resources and grant programs to help offset costs for genetic services, cancer screenings, surgeries, treatments and more.
Public Policy & Advocacy
Go back to previous menu.
Federal Laws
Learn about laws and legal protections affecting the hereditary cancer community—ACA, GINA, WHRCA—and how to file a grievance or complaint.
Federal Policy Efforts
Read about federal laws and legal protections affecting the hereditary cancer community and how to file a grievance or complaint.
Advocacy Day
Learn about Advocacy Day and how you can help educate Congress about important issues faced by people in the hereditary cancer community.
State Laws
Get information on state laws that guide coverage and costs of cancer screenings and diagnostic imaging needed by those at risk of hereditary cancers.
State Policy Efforts
Read about our engagement in key state legislative efforts, ensuring that the voice of the high-risk, hereditary cancer community is represented.
Volunteer
You can make a difference! Learn how you can help FORCE advocate for the hereditary cancer community at the state and federal levels.
Resources
Go back to previous menu.
Educational Resources
Community Resources
Healthcare Provider Resources
Educational Resources
Go back to previous menu.
Behind the Headlines (XRAY)
Our XRAY program takes you behind the headlines to bring you reliable information about cancer research-related news and information.
Blog
Education and personal perspectives on topics of interest to our community.
Glossary
Find definitions for commonly used terms.
Brochures
Order or download our educational materials.
Webinars
Our live and on demand webinars feature presentations by experts on topics of interest and importance to our community.
Community Resources
Go back to previous menu.
Previvors
Information and resources that address the unique needs of the previvor community.
LGBTQIA+
Information and resources for people who identify with the LGBTQIA+ community and who have an inherited mutation linked to cancer.
Health Disparity Resources
Information and resources focused on addressing cancer health disparities.
Lynch Syndrome
Learn about Lynch syndrome and find information, resources and research specifically for the Lynch syndrome community.
En Español
¿El cáncer en su familia es hereditario? Aprenda sobre la prueba genética para identificar el riego de cáncer hereditario y los pasos a seguir para proteger su salud y la de su familia
FORCE Partners
Learn about organizations we work with to advocate for greater awareness, broader access to care, and better treatment and prevention options for all those who are impacted by hereditary cancer.
Healthcare Provider Resources
Go back to previous menu.
For Healthcare Providers
Information and resources for members of the healthcare or research community who focus on hereditary cancers.
For Researchers
Tips and tools to help investigators work with patient stakeholders to strengthen and accelerate their research.
Donate
About Us
Español
Close menu
Hereditary Cancers
Genetic Testing
Hereditary Cancer Basics
Learn how gene mutations can lead to cancer, what types of cancer may be hereditary and how parents can pass inherited mutations to their children.
Cancer Risks by Gene
Read about different genes that are linked to hereditary cancer and the risks associated with inherited mutations in these genes.
How Do I Get Genetic Testing?
Learn more about genetic testing and how to take the next steps to get tested.
After Testing Now What
Learn how to make medical decisions and assemble your health care team once you receive your genetic test results.
Sharing Results with Family
Explore tips to help you communicate your family medical history or genetic test results with relatives.
Close menu
Risk Management & Treatment by Mutation & Cancer
Reconstruction or Going Flat
Menopause, Well-Being & Survivorship
Fertility & Family Planning
Risk Management & Treatment by Mutation
Review updated information on cancer risks and national guidelines on screening, prevention and treatment options listed by gene.
Risk Management & Treatment by Cancer
Review updated information on screening, prevention and treatment options listed by cancer site.
Risk Management & Treatment by Treatment Type
Review information on prevention and treatment options listed by treatment type
Risk Management for Transgender People
Review guidelines on prevention and screening options for transgender people with inherited mutations.
Types of Reconstruction
Understand the types of breast reconstruction.
Going Flat
Learn more about the option of going flat.
Preparation and Recovery
Prepare for surgery and recovery.
Photo and Video Gallery
See images & videos of individuals after mastectomy and reconstruction.
Menopause
Learn about ways to manage the effects of menopause with and without hormones.
Well-Being & Survivorship
Learn how to manage the short- and long-term effects of cancer risk, diagnosis, prevention and treatment.
Close menu
Enroll in Research
Research Advocacy
Search and Enroll
Ready to enroll? Our tools will help match you to hereditary cancer detection, prevention and treatment studies.
How to Find Studies
These tips and resources will help you locate clinical trials and studies enrolling people like you.
Why Enroll in Research?
Learn why you should consider enrolling in a research study and your rights and protections as a research participant.
Help Shape Research
FORCE trains patients with no science background to use their personal experiences to help guide hereditary cancer research.
Resources for Researchers
These tips and resources were developed by research advocates to help investigators work with patient stakeholders to strengthen and accelerate their research.
Close menu
Support
Paying for Care
Public Policy & Advocacy
Personalized Guidance
Match with a Peer Navigator volunteer with similar experience as you for confidential 1:1 phone/email support and a free resource guide.
Support Meetings & Partner Events
Review our calendar to connect with others and obtain support and vital resources.
Private Facebook Group
Connect with others over social media who are affected by hereditary cancer.
Message Boards
Register for our forum where you can discuss topics online 24/7 with other people who face similar hereditary cancer concerns.
Helpline
Ask questions and receive nonjudgmental support and resources in English and Spanish. A Genetic Counselor helpline is also available.
Decision Checklists and Tip Sheets
Use our interactive tool to create personalized lists of questions to ask your doctors and tips to prepare for surgeries and procedures.
Find Healthcare Providers
Locate services or medical experts knowledgeable in cancer genetics, including genetic counselors, oncologists, surgeons, fertility experts and more.
Volunteer
Get involved by supporting others, advocating for laws and research that benefit our community and raising awareness of hereditary cancer on social media.
Insurance & Reimbursement
Learn about health insurance coverage and reimbursement for healthcare services. Get tips on insurance appeals and customizable sample appeal letters.
Financial Assistance
Find national resources and grant programs to help offset costs for genetic services, cancer screenings, surgeries, treatments and more.
Federal Laws
Learn about laws and legal protections affecting the hereditary cancer community—ACA, GINA, WHRCA—and how to file a grievance or complaint.
Federal Policy Efforts
Read about federal laws and legal protections affecting the hereditary cancer community and how to file a grievance or complaint.
Advocacy Day
Learn about Advocacy Day and how you can help educate Congress about important issues faced by people in the hereditary cancer community.
State Laws
Get information on state laws that guide coverage and costs of cancer screenings and diagnostic imaging needed by those at risk of hereditary cancers.
State Policy Efforts
Read about our engagement in key state legislative efforts, ensuring that the voice of the high-risk, hereditary cancer community is represented.
Volunteer
You can make a difference! Learn how you can help FORCE advocate for the hereditary cancer community at the state and federal levels.
Close menu
Educational Resources
Community Resources
Healthcare Provider Resources
Behind the Headlines (XRAY)
Our XRAY program takes you behind the headlines to bring you reliable information about cancer research-related news and information.
Blog
Education and personal perspectives on topics of interest to our community.
Glossary
Find definitions for commonly used terms.
Brochures
Order or download our educational materials.
Webinars
Our live and on demand webinars feature presentations by experts on topics of interest and importance to our community.
Previvors
Information and resources that address the unique needs of the previvor community.
LGBTQIA+
Information and resources for people who identify with the LGBTQIA+ community and who have an inherited mutation linked to cancer.
Health Disparity Resources
Information and resources focused on addressing cancer health disparities.
Lynch Syndrome
Learn about Lynch syndrome and find information, resources and research specifically for the Lynch syndrome community.
En Español
¿El cáncer en su familia es hereditario? Aprenda sobre la prueba genética para identificar el riego de cáncer hereditario y los pasos a seguir para proteger su salud y la de su familia
FORCE Partners
Learn about organizations we work with to advocate for greater awareness, broader access to care, and better treatment and prevention options for all those who are impacted by hereditary cancer.
For Healthcare Providers
Information and resources for members of the healthcare or research community who focus on hereditary cancers.
For Researchers
Tips and tools to help investigators work with patient stakeholders to strengthen and accelerate their research.
Get notified of page updates
Research & Clinical Trials
/
Research Search & Enroll Tool
/ Search Results
Search Results: Treatment + Breast Cancer + Stage 4 (0 results)
New Search
Additional Results on Clinicaltrials.gov Treatment + Breast Cancer + Stage 4 + HER2-Positive
41 results
Clinical Trial
Official Title
NCT06388122
DiviTum®TKa: A Biomarker Assay for Efficacy in HR+ Metastatic Breast Cancer Patients
NCT07112053
A Vaccine (STEMVAC) With Standard Endocrine-Based Therapy or Chemotherapy for the Treatment of Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer
NCT05183828
Effect of HSD3B1 (1245C) Gene Mutation on Treatment of Stage I-III Breast Cancer
NCT06590857
Trial of 225Ac-DOTATATE (RYZ101) in Subjects With ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.
NCT04143711
Study of DF1001 in Patients with Advanced Solid Tumors
NCT04550494
Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations
NCT04923542
Stereotactic Radiation & Abemaciclib in the Management of HR+/HER2- Breast Cancer Brain Metastases
NCT05150691
A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors
NCT03697577
CDK and Body Composition Study
NCT04517838
Immune Response to Anti-HER2 Therapies in Patients With HER2-Positive Stage I-IV Breast Cancer
NCT04704661
Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial
NCT05098210
Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer
NCT06878248
A Study to Assess CLBR001+ABBV-461 in Subjects With Locally Advanced or Metastatic Breast Cancer
NCT06678269
A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer
NCT05894239
A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer
NCT05564377
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
NCT04588545
Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in HER2+ Breast Leptomeningeal Disease
NCT05795101
TRUDI: TDXD+Durva in HER2+/Low IBC
NCT06993844
Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors
NCT05378464
Adoptive T Cell Therapy Following HER2-Pulsed Dendritic Cell Vaccine & Pepinemab /Trastuzumab in Patients w/ Metastatic HER2+ Breast Cancer
NCT06525766
Adaptive Therapy With Capecitabine for Treatment of Metastatic ER Positive, HER2 Negative Breast Cancer
NCT06867484
Breast Re-irradiation After Second Ipsilateral Lumpectomy
NCT04567420
DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)
NCT04899908
Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases
NCT06179303
Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer
NCT06876714
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
NCT06172127
PHESGO Maintenance After T-DXd Short Induction for HER2+ Unresectable Locally Recurrent or Metastatic Breast Cancer
NCT06686394
Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)
NCT06471673
A Study of BRIA-OTS Cellular Immunotherapy in Metastatic Recurrent Breast Cancer
NCT06247995
A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.
NCT04683679
A Study of Radiation Therapy With Pembrolizumab and Olaparib or Other Radiosensitizers in Women Who Have Triple-Negative or Hormone-Receptor Positive/Her2 Negative Breast Cancer
NCT03424005
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
NCT05826964
Levels of Circulating Tumor DNA as a Predictive Marker for Early Switch in Treatment for Patients With Metastatic (Stage IV) Breast Cancer
NCT06055881
Primary Breast Oligoprogressive Sites Treated With Radiotherapy to Obviate the Need to Change Systemic Therapy
NCT05879926
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
NCT07053085
A Study of Surgery and Radiotherapy in People With Breast Cancer
NCT04852887
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
NCT05059444
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
NCT05130840
Monitoring for Cancer Spread to the Central Nervous System (CNS) in People With Breast Cancer
NCT06833502
Phase II Study of Systemic Screening in Pathologic Node Positive Breast Cancer
NCT05417594
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
Knowledge Can Save Lives
Receive FORCE Newsletters
Stay up to date on hereditary cancer information.
First Name
*
Last Name
*
Email
*
What is your primary connection to hereditary cancer?
*
-choose-
I have or have had hereditary cancer.
I have a family history of cancer but have not had cancer (previvor).
My loved one has or has had hereditary cancer.
I am a healthcare provider.
Other
Name
Time
Sign Up
Top
Go to top
×
Knowledge Can Save Lives
Stay up to date on hereditary cancer information.
First Name
*
Last Name
*
Email
*
What is your primary connection to hereditary cancer?
*
-choose-
I have or have had hereditary cancer.
I have a family history of cancer but have not had cancer (previvor).
My loved one has or has had hereditary cancer.
I am a healthcare provider.
Other
Name
Time
Sign Up
Read our
privacy policy
.
×