https://www.facingourrisk.org/research-clinical-trials/study/330/screening-study-for-pancreatic-cancer
Prevention
Pancreatic cancer screening study for people with BRCA, ATM, or PALB2 genetic mutations
This study will look at how often routine MRI scans detect abnormal findings in people with genetic mutations linked to hereditary cancer, specifically BRCA1, BRCA2, ATM, and PALB2, who are undergoing pancreatic cancer screening. Researchers aim to determine how frequent there are abnormal MRI and endoscopic ultrasound (EUS) results, as well as the occurrence of high-grade pancreatic precancerous lesions and pancreatic cancer. The study will also review the rate of procedures like biopsies and surgeries among participants.
https://www.facingourrisk.org/research-clinical-trials/study/222/pancreatic-cancer-screening-studycaps5
Prevention
Screening study for people at high risk for pancreatic cancer
CAPS5 is a study looking at screening for early cancer in people with an elevated lifetime risk of developing pancreatic cancer. The goal is to study biomarkers derived from images and tissue samples (blood, pancreas fluid, duodenal fluid) for the early detection of pancreatic cancer and precancerous lesions.
https://www.facingourrisk.org/research-clinical-trials/study/227/pancreatic-cancer-early-detection-for-people-at-high-risk
Prevention
Registry and biobank for high risk people undergoing pancreatic cancer screening
The study will collect clinical information, family history, and samples (blood, saliva or cheek swab) from people and families at risk for pancreatic cancer. Collecting this information and samples will create a resource to drive research necessary for early detection and prevention of pancreatic ductal adenocarcinoma (PDAC).
https://www.facingourrisk.org/research-clinical-trials/study/141/blood-markers-of-early-pancreas-cancer
Prevention
Observational study for people with family history of pancreas cancer or an inherited mutation linked to pancreatic cancer risk
The purpose of this study is to try to find markers of early pancreatic cancer for individuals at higher-than-average risk, expedite the diagnosis in individuals with symptoms, and substantially improve an individual's chance of surviving the disease.
https://www.facingourrisk.org/research-clinical-trials/study/95/pancreatic-cancer-screening-study-for-high-risk-people
Prevention
Screening study to detect pancreatic cancer and precancer in people with either a strong family history of pancreatic cancer, or an inherited mutation associated with pancreatic cancer risk
The purpose of this study is to screen and detect pancreatic cancer and precancer in people with either a strong family history of pancreatic cancer, or an inherited mutation associated with pancreatic cancer risk.
Magnetic Resonance Imaging (MRI) will be used to screen for early stage pancreatic cancer. Participants will also be asked to donate a blood sample at specific intervals for the creation of a blood bank necessary for the development of a blood-based screening test for pancreatic cancer.
Additional Results on Clinicaltrials.gov Prevention, Detection & Risk + Pancreatic Cancer + Screening & Early Detection
8 results
Blood Markers of Early Pancreas Cancer
NCT ID: NCT03568630 (https://clinicaltrials.gov/study/NCT03568630)
DNA Evaluation of Fragments for Early Interception - Lung Cancer Training Study (DELFI-L101 Study)
NCT ID: NCT04825834 (https://clinicaltrials.gov/study/NCT04825834)
Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals
NCT ID: NCT06122896 (https://clinicaltrials.gov/study/NCT06122896)
Preliminary Evaluation of Screening for Pancreatic Cancer in Patients with Inherited Genetic Risk
NCT ID: NCT02478892 (https://clinicaltrials.gov/study/NCT02478892)
Pancreatic Cancer Detection Consortium
NCT ID: NCT06388967 (https://clinicaltrials.gov/study/NCT06388967)
A Prospective Registry for Patients at High-Risk for Pancreatic Cancer
NCT ID: NCT06151223 (https://clinicaltrials.gov/study/NCT06151223)
A Pancreatic Cancer Screening Study in Hereditary High Risk Individuals
NCT ID: NCT03250078 (https://clinicaltrials.gov/study/NCT03250078)
A Pancreatic Cancer Screening Study in Individuals With New-Onset or Deteriorating Diabetes Mellitus
NCT ID: NCT03937453 (https://clinicaltrials.gov/study/NCT03937453)
FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.