Search Results: Prevention, Detection & Risk + Ovarian Cancer + Risk Reduction (3 results)
Acting on Cancer Testing Together (ACT-Together)
https://www.facingourrisk.org/research-clinical-trials/study/326/acting-on-cancer-testing-together-act-together
Prevention
This is a study for women diagnosed with BRCA 1 or BRCA2 focused on increasing education on options for reducing cancer risk associated with their diagnosis
The goal of this research study is to develop a new education program, called the ACT-Together intervention, to educate and support women who test positive for the BRCA1 or BRCA2 mutation on how they can reduce their risk of cancer in an online group setting.
A Study to Compare Two Surgical Procedures in Women with BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer (SOROCk)
https://www.facingourrisk.org/research-clinical-trials/study/101/a-study-to-compare-two-surgical-procedures-in-women-with-brca1-mutations-to-assess-reduced-risk-of-ovarian-cancer-sorock
Prevention
Ovarian cancer prevention for women with a BRCA1 mutation who still have their ovaries
SOROCk [NRG-CC008] is a clinical trial studying if removal of just the fallopian tubes can reduce the risk of ovarian cancer nearly as much as removing both the ovaries and fallopian tubes among women with an inherited BRCA1 mutation. The main benefit of removing only the fallopian tubes and not the ovaries is to prevent surgically-induced menopause. The study will also examine various patient-reported quality of life outcomes. Researchers believe that most ovarian cancers first begin in the fallopian tubes, suggesting that removing the fallopian tubes only may prevent the development of ovarian cancer. This concept has never been formally testing in a clinical trial.
Risk Reducing Salpingectomy With Delayed Oophorectomy as an Alternative to Risk- Reducing Salpingo-oophorectomy in High-Risk Women (TUBA/WISP II)
https://www.facingourrisk.org/research-clinical-trials/study/205/risk-reducing-salpingectomy-with-delayed-oophorectomy-as-an-alternative-to-risk-reducing-salpingo-oophorectomy-in-high-risk-women
Prevention
Prevention study for women at high risk for ovarian cancer
This study is looking at whether removal of the fallopian tubes (salpingectomy) followed by removal of the ovaries (oophorectomy) at a later date closer to the time of natural menopause may reduce the risk of ovarian cancer nearly as much as removing both the ovaries and fallopian tubes at the same time (salpingo-oophorectomy) among women with an inherited BRCA1, BRCA2, BRIP1, RAD51C or RAD51D mutation. Removing the fallopian tubes only first and the ovaries at a later time closer to natural menopause may lessen menopausal symptoms while still lowering the risk for ovarian cancer.
Additional Results on Clinicaltrials.gov Prevention, Detection & Risk + Ovarian Cancer + Risk Reduction
3 results
TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention
NCT ID: NCT04294927 (https://clinicaltrials.gov/study/NCT04294927)
A Study of Opportunistic Salpingectomy to Prevent Ovarian Cancer
NCT ID: NCT06312124 (https://clinicaltrials.gov/study/NCT06312124)
Risk Reducing Salpingectomy With Delayed Oophorectomy as an Alternative to Risk- Reducing Salpingo-oophorectomy in High Risk-Women to Assess the Safety of Prevention - US Cohort Study
NCT ID: NCT05287451 (https://clinicaltrials.gov/study/NCT05287451)
About FORCE
FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.