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Our Featured Research Page lists cancer prevention, treatment and quality of life studies enrolling people with or at high risk for hereditary cancers. You can do a quick search to filter our featured studies by cancer type, study type or key word, or a more in-depth search through clinicaltrials.gov.

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Search Results: Prevention, Detection & Risk + Pancreatic Cancer (8 results)

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Pancreatic Cancer Early Detection for People  at High Risk

Prevention
Registry and biobank for high risk people undergoing pancreatic cancer screening

Pancreatic Cancer Early Detection for People at High Risk

The study will collect clinical information, family history, and samples (blood, saliva or cheek swab) from people and families at risk for pancreatic cancer. Collecting this information and samples will create a resource to drive research necessary for early detection and prevention of pancreatic ductal adenocarcinoma (PDAC).

Clinicaltrials.gov identifier: NCT04970056
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Testing  a Vaccine for Cancer Prevention in People with a BRCA1 or BRCA2 Mutation

Prevention
People with a BRCA1 or BRCA2 mutation

Testing a Vaccine for Cancer Prevention in People with a BRCA1 or BRCA2 Mutation

This study will look at a new vaccine known as INO-5401 used alone or combined with a second vaccine called INO-9012. The study will test if the vaccine is safe (without large side effects) and test a new way of giving vaccines. It will also test whether the vaccine activates the immune system. A goal of this research is to reduce cancer risk in people with a BRCA1 or BRCA2 mutation. Additional studies will be needed to learn if this vaccine approach lowers cancer risk in mutation carriers. 

Clinicaltrials.gov identifier: NCT04367675
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Pancreatic Cancer Screening Study (CAPS5)

Prevention
Screening study for people at high risk for pancreatic cancer

Pancreatic Cancer Screening Study (CAPS5)

CAPS5 is a study looking at screening for early cancer in people with an elevated lifetime risk of developing pancreatic cancer. The goal is to study biomarkers derived from images and tissue samples (blood, pancreas fluid, duodenal fluid) for the early detection of pancreatic cancer and precancerous lesions.

 

Clinicaltrials.gov identifier: NCT02000089
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Blood Markers of Early Pancreas Cancer

Prevention
Observational study for people with family history of pancreas cancer or an inherited mutation linked to pancreatic cancer risk.

Blood Markers of Early Pancreas Cancer

The purpose of this study is to try to find markers of early pancreatic cancer for individuals at higher-than-average risk, expedite the diagnosis in individuals with symptoms, and substantially improve an individual's chance of surviving the disease.

Clinicaltrials.gov identifier: NCT03568630
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Helping People With a Genetic Mutation in BRCA1, BRCA2 or Lynch Syndrome Talk to Their Family Members About Their Risk for Cancer and Find the Best Way to Get Family Members Tested

Prevention
People with a genetic mutation in BRCA1, BRCA2 or Lynch syndrome who have relatives who have not been tested

IGNITE-TX - Identifying Individuals for Genetic Testing for Familial Cancer

The IGNITE-TX study is all about helping people with a genetic mutation in BRCA1, BRCA2 or Lynch syndrome talk to their family members about their risk for cancer and find the best way to get family members tested.

Clinicaltrials.gov identifier: NCT05677048
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Screening for Pancreatic Cancer in Patients with an Inherited BRCA1, BRCA2, PALB2 or ATM Mutation

Prevention

Preliminary Evaluation of Screening for Pancreatic Cancer in Patients with an Inherited Genetic Risk Due to a BRCA1, BRCA2, PALB2 or ATM Mutation

Improved screening for pancreatic cancer in high-risk groups, such as people with an inherited BRCA1, BRCA2, ATM, or PALB2 mutation, may help find cancer early and improve survival rates. People enrolled in this study will undergo screening using endoscopic ultrasound or MRI of the abdomen.

Clinicaltrials.gov identifier: NCT02478892
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Pancreatic Cancer Screening Study for High Risk People

Prevention

A Pancreatic Cancer Screening Study for High Risk Individuals

The purpose of this study is to screen and detect pancreatic cancer and precancer in people with either a strong family history of pancreatic cancer, or an inherited mutation associated with pancreatic cancer risk.

Magnetic Resonance Imaging (MRI) will be used to screen for early stage pancreatic cancer. Participants will also be asked to donate a blood sample at specific intervals for the creation of a blood bank necessary for the development of a blood-based screening test for pancreatic cancer. 

Clinicaltrials.gov identifier: NCT03250078
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Pancreatic Cancer Early Detection

Prevention

Pancreatic Cancer Early Detection Program

This is a study looking at esophageal ultrasound and Magnetic Resonance Imaging (MRI) as a screening for pancreatic cancer in high risk individuals. 

Clinicaltrials.gov identifier: NCT02206360
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