Use our HBOC Research Search tool to find and participate in research focused on hereditaty cancers. Need assistance getting started?
Here are some research studies that may be enrolling patients like you. Please check with the study contact and your health care provider to confirm your eligibility and see if the study is right for you. Note, our search tool may not be comprehensive and additional research resources can be found here.
This is a study looking at esophageal ultrasound and Magnetic Resonance Imaging (MRI) as a screening for pancreatic cancer in high risk individuals.
BFOR is a research study looking at ways to make genetic testing easier. It offers BRCA testing at no cost to men and women age 25 or older, who have at least one Ashkenazi Jewish grandparent. The study is open to people who live in the Boston, New York, Los Angeles or Philadelphia metropolitan areas. For more information, visit the BFOR study website.
The goal of the GENERATE study is to increase the uptake of genetic testing among family members of pancreatic cancer patients who carry a genetic mutation.
This study involves education about genetic testing, undergoing genetic testing for cancer risk and completion of a series of 4 sets of questionnaires.
The study is not yet open but you can complete the Contact Form to be notified when the study begins enrolling.
The goal of this research study is to determine if online genetic education and testing with online telephone genetic counseling is an acceptable method of delivering genetic testing to men with metastatic prostate cancer.
This study involves undergoing genetic counseling and genetic testing for inherited cancer risk.
The goal of this research study is to test the effects of online genetic education alone or in combination with telephone genetic counseling in order to compare the two methods and the stress a person feels about their risk of cancer.
Researchers also want to learn how these strategies may improve your understanding of genetics, your ability to complete a quiz about genetics, and your quality of life.
The Genetic Education for Men or GEM study, is a clinical trial evaluating educational tools for men from families in which a BRCA1/2 gene mutation has been identified. In order to identify untested men from BRCA1/2 families, we are seeking women who have received positive BRCA1/2 test results and have at least one untested male relative.
Women interested in the study should contact the project coordinator, Mary Kate Ladd, by phone at (877) 687-2720 (toll-free) or by email.
The purpose of this research study is to test whether metformin, a drug commonly used to treat diabetes, is able to get rid of atypia (early cell changes that are thought to be a marker of breast cancer risk) in women at increased risk for breast cancer. There will be testing for the presence of atypia in the breast after metformin is given to see if it can get rid of atypia. The study will compare the effects, good and/or bad, of metformin or placebo on atypia to find out which is better.
Quality of Life:
High Risk But No Cancer
The goal of the WISP Study is to compare whether removal of fallopian tubes only, delaying removal of the ovaries can safely improve sexual functioning and menopausal symptoms compared to standard risk-reducing removal of the ovaries and fallopian tubes (also known as risk-reducing salpingo-oophorectomy or RRSO). You can visit the WISP website for more information.
In this study, researchers want to determine the optimal amount of exercise needed to change certain factors associated with breast cancer risk for post-menopausal, high-risk women.
Visit the study website for more information.
The goal of the Wisdom Study is to determine if breast cancer screening can be made better by personalizing each woman’s mammogram schedule, compared to the current one-size-fits-all, annual approach. The Wisdom Study is designed to end the confusion about when to start and how often to have a mammogram. For more information, visit the WISDOM Study website.
|Clinical Trial||Official Title|
|NCT02310698||Comparison of Whole Breast Screening Ultrasound and Contrast Enhanced Mammography for Supplemental Breast Cancer Screening|
|NCT03180086||Breast Cancer Risk Assessment in Women Aged 40-49|
|NCT03482557||Contrast Enhanced Spectral Mammography vs. MRI for Breast Cancer Screening|
|NCT03495115||Comparing Restriction Spectrum Imaging (RSI) to Conventional and Abbreviated Breast MRI for Breast Cancer Screening|
|NCT03408353||Early Detection of Breast Cancer in a Mammography Screening|
|NCT03250078||A Pancreatic Cancer Screening Study in High Risk Individuals|
|NCT02154672||Prostate Cancer Screening in Men With Germline BRCA2 Mutations|
|NCT03474913||Upright MRI for Prostate Cancer Screening|
|NCT02478892||Screening for PDAC in BRCA1/2 Patients|
|NCT03729115||A Multi-Modality Surveillance Program for Women at High Risk for Breast Cancer|
|NCT02068092||Olive Oil for High Risk Breast Cancer Prevention in Women|
|NCT03859492||Screening CEDM in Intermediate and High-Risk Patient Populations|
|NCT03069742||Study of Web-based Decision Aids for Increasing Breast Cancer Chemoprevention in the Primary Care Setting|
|NCT02511301||Circadian Thermal Sensing to Detect Breast Disease|
|NCT02470273||Diagnostic Imaging Study for the Melanoma Advanced Imaging Dermatoscope (mAID)|
|NCT03448003||Comprehensive Lifestyle Change To Prevent Breast Cancer|
|NCT03629717||RANKL Inhibition and Breast Tissue Biomarkers|
|NCT01900821||National Mammography Database|
|NCT03623945||Autoantibodies in Breast Cancer Detection|
|NCT03471650||Study of PSMA-targeted 18F-DCFPyL PET/CT for the Detection of Clinically Significant Prostate Cancer|
|NCT03654638||Soy Bread Diet in Improving Immune Function in Participants With Prostate Cancer|
|NCT03178383||Integration of Cancer Health Activities Into African American Churches|
|NCT01035112||Magnetic Resonance Imaging of Breast Cancer|
|NCT03645005||A Research Study for Latina Women After Breast Cancer Treatment|
|NCT03568630||Blood Markers of Early Pancreas Cancer|
|NCT00291096||Protocol for Women at Increased Risk of Developing Breast Cancer|
|NCT03837496||Small-group, Virtual Program for Improving Symptoms and Distress Related to Hormonal Therapy for Breast Cancer Survivors|
|NCT03313492||Modifying Young Adult Skin Cancer Risk and Protective Behaviors|
|NCT03075540||Enhancing At-risk Latina Women's Use of Genetic Counseling for Hereditary Breast and Ovarian Cancer|
|NCT02760849||The Women Choosing Surgical Prevention (WISP) Trial|
|NCT02771769||Analysis of Cell-free DNA (cfDNA) in Men With Elevated PSA Levels|
|NCT02033486||Digital Breast Tomosynthesis Guided Tomographic Optical Breast Imaging (TOBI)|
|NCT02229565||Molecular Mechanisms Underlying Prostate Cancer Disparities|
|NCT03288792||A Evaluation of 3D Functional MIRA System in Women With Mammographically Dense Breasts|
|NCT02206360||Pancreatic Cancer Early Detection Program|
|NCT03470402||Decision Support for BRCA Testing in Ethnically Diverse Women|
|NCT03060941||Promoting Activity in Cancer Survivors|
|NCT03693378||A Study of IMMray™ PanCan-d Test for Early Detection of Pancreatic Cancer in High-risk Groups|
|NCT00539162||Use of the CA 125 Algorithm for the Early Detection of Ovarian Cancer in Low Risk Women|
|NCT00579514||Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients|
|NCT00579488||Clinical Significance of Germline BRCA Mutations|
|NCT02657993||Hypnosis to Reduce Aromatase Inhibitor Pain and Improve Adherence|
|NCT03141437||Patient-Centered Decision Counseling for Women at Risk of Cancer-Related Infertility|
|NCT03851133||Florida Pancreas Collaborative Next Generation Biobank|
|NCT03426878||Cancer Health Assessments Reaching Many|
|NCT03006562||PREvention of VENous ThromboEmbolism Following Radical Prostatectomy|
|NCT02694809||The PROMISE Study: Duavee in Women With DCIS|
|NCT02928978||Ruxolitinib for Premalignant Breast Disease|
|NCT01247597||DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study|