Research Study Search Tool

Use our HBOC Research Search tool to find and participate in research focused on hereditaty cancers. Need assistance getting started?

Search Results: Prevention, Detection & Risk (11 results)

Here are some research studies that may be enrolling patients like you. Please check with the study contact and your health care provider to confirm your eligibility and see if the study is right for you. Note, our search tool may not be comprehensive and additional research resources can be found here.

BRCA Founder Outreach Study (BFOR)

Prevention:
Breast
Ovarian
Pancreatic
Prostate

BRCA Founder Outreach Study (BFOR)

BFOR is a research study looking at ways to make genetic testing easier. It offers BRCA testing at no cost to men and women age 25 or older, who have at least one Ashkenazi Jewish grandparent. The study is open to people who live in the Boston, New York, Los Angeles or Philadelphia metropolitan areas. For more information, visit the BFOR study website

The Women Choosing Surgical Prevention (WISP) Trial

Prevention:
Ovarian

Quality of Life:
High Risk But No Cancer

The Women Choosing Surgical Prevention (WISP) Trial

The goal of the WISP Study is to compare whether removal of fallopian tubes only, delaying removal of the ovaries can safely improve sexual functioning and menopausal symptoms compared to standard risk-reducing removal of the ovaries and fallopian tubes (also known as risk-reducing salpingo-oophorectomy or RRSO). You can visit the WISP website for more information.

 

Making Genetic Testing Accessible (MAGENTA)

Prevention:
Breast
Ovarian

Making Genetic Testing Accessible (MAGENTA)

The goal of this research study is to test the effects of online genetic education alone or in combination with telephone genetic counseling in order to compare the two methods and the stress a person feels about their risk of cancer.

Researchers also want to learn how these strategies may improve your understanding of genetics, your ability to complete a quiz about genetics, and your quality of life.

For more information, visit the study website

Men at High Genetic Risk for Prostate Cancer

Prevention:
Prostate

Men at High Genetic Risk for Prostate Cancer

couvilla@mail.nih.govThe National Cancer Institute recently opened a clinical trial for prostate cancer screening in men who are at high risk for prostate cancer due to an inherited mutation.

GENetic Education Risk Assessment and TEsting Study (GENERATE)

Prevention:
Pancreatic

GENetic Education Risk Assessment and TEsting Study (GENERATE)

The goal of the GENERATE study is to increase the uptake of genetic testing among family members of pancreatic cancer patients who carry a genetic mutation.

This study involves education about genetic testing, undergoing genetic testing for cancer risk and completion of a series of 4 sets of questionnaires.

For more information, visit the study website

Pancreatic Cancer Early Detection Program

Prevention:
Pancreatic

Pancreatic Cancer Early Detection Program

This is a study looking at esophageal ultrasound and Magnetic Resonance Imaging (MRI) as a screening for pancreatic cancer in high risk individuals. 

GENTleMEN Study: Genetic Testing for Men with Metastatic Prostate Cancer

GENTleMEN Study: Genetic Testing for Men with Metastatic Prostate Cancer

The goal of this research study is to determine if online genetic education and testing with online telephone genetic counseling is an acceptable method of delivering genetic testing to men with metastatic prostate cancer.

This study involves undergoing genetic counseling and genetic testing for inherited cancer risk.

 

A Study in Hereditary Breast and Ovarian  Cancer Families to Provide Men With  Up-To-Date Information About the Personal  Importance of Genetic Testing (GEM)

Prevention:
Pancreatic
Prostate

A Study in Hereditary Breast and Ovarian Cancer Families to Provide Men With Up-To-Date Information About the Personal Importance of Genetic Testing (GEM)

The Genetic Education for Men or GEM study, is a clinical trial evaluating educational tools for men from families in which a BRCA1/2 gene mutation has been identified. In order to identify untested men from BRCA1/2 families, we are seeking women who have received positive BRCA1/2 test results and have at least one untested male relative.

Women interested in the study should contact the project coordinator, Mary Kate Ladd, by phone at (877) 687-2720 (toll-free) or by email.

Metformin Hydrochloride in Patients With Atypical Hyperplasia or In Situ Breast Cancer to Placebo in Decreasing Atypical Cells in Patients With Atypical Hyperplasia or in Situ Breast Cancer

Prevention:
Breast

Metformin Hydrochloride in Patients With Atypical Hyperplasia or In Situ Breast Cancer to Placebo in Decreasing Atypical Cells in Patients With Atypical Hyperplasia or in Situ Breast Cancer

The purpose of this research study is to test whether metformin, a drug commonly used to treat diabetes, is able to get rid of atypia (early cell changes that are thought to be a marker of breast cancer risk) in women at increased risk for breast cancer. There will be testing for the presence of atypia in the breast after metformin is given to see if it can get rid of atypia. The study will compare the effects, good and/or bad, of metformin or placebo on atypia to find out which is better.

Dose-Response of Aerobic Training in Post-Menopausal Women at High-Risk for Development of Breast Cancer

Prevention:
Breast

Dose-Response of Aerobic Training in Post-Menopausal Women at High-Risk for Development of Breast Cancer

In this study, researchers want to determine the optimal amount of exercise needed to change certain factors associated with breast cancer risk for post-menopausal, high-risk women.

Visit the study website for more information.

The WISDOM Study: Women Informed to Screen Depending on Measures of risk

Prevention:
Breast

The WISDOM Study: Women Informed to Screen Depending on Measures of risk

The goal of the Wisdom Study is to determine if breast cancer screening can be made better by personalizing each woman’s mammogram schedule, compared to the current one-size-fits-all, annual approach. The Wisdom Study is designed to end the confusion about when to start and how often to have a mammogram. For more information, visit the WISDOM Study website

Additional Results on Clinicaltrials.gov: Prevention, Detection & Risk

53 Results

Clinical Trial Official Title
NCT03979729 Breast Cancer Screening for Underserved Women: Comparing Outcomes and Lowering Recall Rates With 3D- vs. 2D-mammography
NCT02310698 Comparison of Whole Breast Screening Ultrasound and Contrast Enhanced Mammography for Supplemental Breast Cancer Screening
NCT03180086 Breast Cancer Risk Assessment in Women Aged 40-49
NCT03482557 Contrast Enhanced Spectral Mammography vs. MRI for Breast Cancer Screening
NCT03495115 Comparing Restriction Spectrum Imaging (RSI) to Conventional and Abbreviated Breast MRI for Breast Cancer Screening
NCT03408353 Early Detection of Breast Cancer in a Mammography Screening
NCT03250078 A Pancreatic Cancer Screening Study in High Risk Individuals
NCT03937453 A Pancreatic Cancer Screening Study in Individuals With New-Onset Diabetes Mellitus
NCT02154672 Prostate Cancer Screening in Men With Germline BRCA2 Mutations
NCT03474913 Upright MRI for Prostate Cancer Screening
NCT02478892 Screening for PDAC in BRCA1/2 Patients
NCT03729115 A Multi-Modality Surveillance Program for Women at High Risk for Breast Cancer
NCT02068092 Olive Oil for High Risk Breast Cancer Prevention in Women
NCT03859492 Screening CEDM in Intermediate and High-Risk Patient Populations
NCT03069742 Study of Web-based Decision Aids for Increasing Breast Cancer Chemoprevention in the Primary Care Setting
NCT02511301 Circadian Thermal Sensing to Detect Breast Disease
NCT02470273 Diagnostic Imaging Study for the Melanoma Advanced Imaging Dermatoscope (mAID)
NCT01900821 National Mammography Database
NCT03623945 Autoantibodies in Breast Cancer Detection
NCT04009148 Cascade Testing in Families With Newly Diagnosed Hereditary Breast and Ovarian Cancer Syndrome
NCT03448003 Comprehensive Lifestyle Change To Prevent Breast Cancer
NCT03762590 GENetic Education Risk Assessment and TEsting Study
NCT03471650 Study of PSMA-targeted 18F-DCFPyL PET/CT for the Detection of Clinically Significant Prostate Cancer
NCT03654638 Soy Bread Diet in Improving Immune Function in Participants With Prostate Cancer
NCT03178383 Integration of Cancer Health Activities Into African American Churches
NCT03971591 Men Moving Forward: A Lifestyle Program for African-American Prostate Cancer Survivors
NCT01035112 Magnetic Resonance Imaging of Breast Cancer
NCT03645005 A Research Study for Latina Women After Breast Cancer Treatment
NCT03837496 Small-group, Virtual Program for Improving Symptoms and Distress Related to Hormonal Therapy for Breast Cancer Survivors
NCT00291096 Protocol for Women at Increased Risk of Developing Breast Cancer
NCT03568630 Blood Markers of Early Pancreas Cancer
NCT03075540 Enhancing At-risk Latina Women's Use of Genetic Counseling for Hereditary Breast and Ovarian Cancer
NCT02194387 Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members
NCT02771769 Analysis of Cell-free DNA (cfDNA) in Men With Elevated PSA Levels
NCT02033486 Digital Breast Tomosynthesis Guided Tomographic Optical Breast Imaging (TOBI)
NCT02229565 Molecular Mechanisms Underlying Prostate Cancer Disparities
NCT03953326 HeartPhone Cancer Survivors Trial 2019
NCT02760849 Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations
NCT02206360 Pancreatic Cancer Early Detection Program
NCT03470402 Decision Support for BRCA Testing in Ethnically Diverse Women
NCT03060941 Promoting Activity in Cancer Survivors
NCT03693378 A Study of IMMray™ PanCan-d Test for Early Detection of Pancreatic Cancer in High-risk Groups
NCT00539162 Use of the CA 125 Algorithm for the Early Detection of Ovarian Cancer in Low Risk Women
NCT00579514 Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients
NCT00579488 Clinical Significance of Germline BRCA Mutations
NCT02657993 Hypnosis to Reduce Aromatase Inhibitor Pain and Improve Adherence
NCT03961685 Cancer Activity and Lifestyle Measurement Study
NCT03851133 Florida Pancreas Collaborative Next Generation Biobank
NCT03426878 Cancer Health Assessments Reaching Many
NCT03006562 PREvention of VENous ThromboEmbolism Following Radical Prostatectomy
NCT02694809 The PROMISE Study: Duavee in Women With DCIS
NCT02928978 Ruxolitinib for Premalignant Breast Disease
NCT01247597 DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study

FORCE:Facing Our Risk of Cancer Empowered