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Eligibility criteria (participant must meet ALL criteria below):
*Participants must also have a working email address
People are excluded if they:
For questions about the study, contact Silpa Karipineni, UCSF Clinical Research Coordinator at (415) 885-7604 or by email.
The study offers genetic testing to women and men of Ashkenazi (Eastern European) Jewish ancestry, age 21 or older. This group is at least ten times more likely than the general population to inherit certain kinds of genetic mutations associated with cancer risk. The study is open to people who live in one of the nine Bay Area counties (Alameda, Contra Costa, Marin, Napa, San Francisco, San Mateo, Santa Clara, Solano, Sonoma). By participating in the UCSF Population Health and Cancer Testing (PHACT) study you will be provided with a saliva collection kit from Color Genomics, a genetic laboratory. Thirty genes will be analyzed, including BRCA1 and BRCA2, to identify mutations that increase the chance of cancer in both men and women of Ashkenazi (Eastern European) Jewish ancestry and genetic counseling support will be available with every test. For more information, visit the UCSF Center for BRCA Research.
Here are the steps to participate in the PHACT Study:
Register: This step includes:
Give consent: This step includes:
Get test results
NOTE: Although not required, all participants are provided with access to genetic counseling before genetic testing if they wish. National standard-of-care guidelines recommend genetic counseling before and after genetic testing.
Pamela Munster, MD
University of California, San Francisco
San Francisco, CA