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Research & Clinical Trials > Study Search Tool > PHACT Study: Population Health and Cancer Testing

PHACT Study: Population Health and Cancer Testing

This study is open to:

Eligibility criteria (participant must meet ALL criteria below):

  • You are 21 years old or older
  • You can speak and read in English
  • You have at least one grandparent of Jewish ancestry
  • You live in one of the 9 Bay Area counties (Alameda, Contra Costa, Marin, Napa, San Francisco, San Mateo, Santa Clara, Solano, Sonoma)
  • You have not had a bone marrow transplant
  • You have not had a blood transfusion in the last 7 days
  • You are not receiving treatment for a blood cancer such as leukemia, lymphoma, or multiple myeloma
  • No prior genetic testing for cancer risk
  • No known history of family genetic cancer mutation

*Participants must also have a working email address

This study is not open to:

People are excluded if they:

  • are under age 21
  • have no Ashkenazi Jewish ancestry
  • have previously had genetic testing for cancer risk
  • do not live in the Bay Area
PHACT Study: Population Health and Cancer Testing

PHACT Study

Prevention:
Breast
Melanoma
Ovarian
Pancreatic
Prostate

Study Contact Information

For questions about the study, contact Silpa Karipineni, UCSF Clinical Research Coordinator at (415) 885-7604 or by email.

About the Study

The study offers genetic testing to women and men of Ashkenazi (Eastern European) Jewish ancestry, age 21 or older. This group is at least ten times more likely than the general population to inherit certain kinds of genetic mutations associated with cancer risk. The study is open to people who live in one of the nine Bay Area counties (Alameda, Contra Costa, Marin, Napa, San Francisco, San Mateo, Santa Clara, Solano, Sonoma).  By participating in the UCSF Population Health and Cancer Testing (PHACT) study you will be provided with a saliva collection kit from Color Genomics, a genetic laboratory. Thirty genes will be analyzed, including BRCA1 and BRCA2, to identify mutations that increase the chance of cancer in both men and women of Ashkenazi (Eastern European) Jewish ancestry and genetic counseling support will be available with every test.  For more information, visit the UCSF Center for BRCA Research. 

What the Study Entails

Here are the steps to participate in the PHACT Study:

Register: This step includes:

  • Providing information to confirm your eligibility to participate
  • Answering questions about personal and family history

Give consent: This step includes:

  • Reading and signing the consent form to enroll

Genetic testing

  • Supplying a saliva sample at a UCSF recruitment event or at home through a mailed Color Genomics’ prepaid testing kit

Get test results

  • Receiving your test results from staff at the UCSF Center for BRCA Research.

Follow up

  • Follow-up genetic counseling support will be offered to every participant.

NOTE: Although not required, all participants are provided with access to genetic counseling before genetic testing if they wish. National standard-of-care guidelines recommend genetic counseling before and after genetic testing. 

Study Lead Investigator

Pamela Munster, MD
University of California, San Francisco
San Francisco, CA

Study Locations

California

  • San Francisco, CA: University of California, San Francisco:
    • Contact Silpa Karipineni, Clinical Research Coordinator at: (415) 885-7604

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