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Research & Clinical Trials > Study Search Tool > BRCA Founder Outreach Study (BFOR)

BRCA Founder Outreach Study (BFOR)

This study is open to:

Men and women can participate if:

  • they are age 25 or older

  • at least one of their four grandparents was Ashkenazi Jewish

  • they have medical insurance

  • are able to understand and read the English-language

  • their Zip code falls within the catchment areas accessible to a BFOR designated provider:

    • New York City

    • Boston

    • Philadelphia

    • Los Angeles

This study is not open to:

People are excluded if they:

  • are under age 25
  • have no Ashkenazi Jewish ancestry
  • do not have insurance
  • have previously had BRCA testing
  • do not live in the New York City, Boston, Philadelphia or Los Angeles area
BRCA Founder Outreach Study (BFOR)

BFOR-BRCA Founder Outreach Study identifier:


Study Contact Information

For questions about the study, contact Kenneth Offit, MD, MPH by phone: 646-888-4059 or by email.

About the Study

The study offers BRCA genetic testing to women and men of Ashkenazi (Eastern European) Jewish ancestry, age 25 or older. This group is at least ten times more likely than the general population to inherit certain kinds of BRCA mutations. The study is open to people who live in the Boston, New York, Los Angeles or Philadelphia metropolitan areas. For more information, visit the BFOR study website

What the Study Entails

Here are the steps to Participate in the BFOR Study:

  1. Register: This step includes:
    • Providing information to confirm your eligibility to participate
    • Completing an online education module
    • Completing personal and family history questionnaires
  2. Give consent: This step includes:
    • Reading and signing the consent form to enroll
  3. Genetic testing
    • supplying a blood sample at a Quest Diagnostics lab in your community for analysis. The study will inform you of the closest location.
  4. Get test results
    • Receiving your test results from your primary care physician or a BFOR cancer genetics specialist.
  5. Follow up
    • Follow-up genetic counseling will be provided to those who test positive for  a BRCA mutation. It will also be provided to those testing negative but with a family history of certain types of cancers.
    • All participants will be asked to complete an annual questionnaire for five years after the study.

Study Locations

The following are participating institutions:

  • Los Angeles, CA
    • Cedars-Sinai Medical Center: Contact Beth Karlan, MD at: 310-423-3302    
  • Boston, MA
    • Dana-Farber Cancer Institute: Contact Judy Garber, MD, MPH at: 617-632-5961
  • Boston, MA
    • Beth Israel Deaconess Medical Center: Contact Nadine Tung, MD at:  617-667-7081 
  • New York, NY
    • Memorial Sloan Kettering Cancer Center: Contact Ken Offitt, MD at: 646-888-4059
  • Philadelphia, PA
    • University of Pennsylvania: Contact Susan Domchek, MD at: 215-615-5858

FORCE:Facing Our Risk of Cancer Empowered