Featured Studies Results

Study of a New InvestigationaI Inhibitor to Treat People with Advanced Solid Tumors

Clinicaltrials.gov identifier:
NCT05932862

Treatment
Treatment study for people with advanced solid tumors

Research Study on the Genetics of Breast Cancer

Surveys, Registries, Interviews
This population-based research study aims to enroll at least 10,000 people aged 18 and older who live in the United States. A diagnosis of cancer is NOT required. Participants may receive information about their genetic ancestry for free.

Acting on Cancer Testing Together (ACT-Together)

Prevention
This is a study for women diagnosed with BRCA 1 or BRCA2 focused on increasing education on options for reducing cancer risk associated with their diagnosis

Olaparib with Cediranib or Ceralasertib for People with Advanced or Metastatic Breast Cancer and with a BRCA1 or BRCA2 Mutation

Clinicaltrials.gov identifier:
NCT04090567

Treatment
Treatment study for people with advanced breast cancer who have a BRCA1 or BRCA2 genetic mutation and who were previously treated with a PARP inhibitor

Sexual Health and Rehabilitation Online (SHAREonline): An Educational Intervention for Young Women after Cancer

Clinicaltrials.gov identifier:
NCT06458049

Quality of Life
An online study comparing two educational interventions for female cancer survivors experiencing sexual health changes

Immunotherapy and PARP Inhibitor for Advanced or Metastatic Breast, Ovarian or Pancreatic Cancer with a BRCA Mutation

Clinicaltrials.gov identifier:
NCT04673448

Treatment
Treatment study for people with advanced breast, ovarian or pancreatic cancer and an inherited or tumor BRCA mutation

Roadmap to Parenthood: A Study about Fertility and Family-Building After Cancer

Clinicaltrials.gov identifier:
NCT06050135

Surveys, Registries, Interviews
A survey for people aged 18-45, assigned female at birth, and history of a cancer diagnosis

New Treatment in People with Triple Negative Breast Cancer or Advanced Solid Tumors

Clinicaltrials.gov identifier:
NCT06022029

Treatment
Treatment study for people with triple negative breast cancer, advanced solid tumors or lymphomas

ShareForCures®: Susan G. Komen's People-Powered, Data-Driven Breast Cancer Research Registry

Clinicaltrials.gov identifier:
NCT05654246

Surveys, Registries, Interviews
Registry for anyone diagnosed with breast cancer

Testing a Vaccine for Treating or Preventing Triple-Negative Breast Cancer

Clinicaltrials.gov identifier:
NCT04674306

Treatment
Treatment study for people with stage 2 or 3 triple-negative breast cancer at high risk for recurrence

Testing a Vaccine for Preventing or Treating Triple-Negative Breast Cancer

Clinicaltrials.gov identifier:
NCT04674306

Prevention
Prevention study for people with a BRCA1, BRCA2 or PALB2 inherited mutation who are planning to undergo risk-reducing mastectomy

Study of the PARP inhibitor AZD9574 Alone and Combined with Other Cancer Medicines to Treat People with Advanced Solid Cancers (CERTIS1 Study)

Clinicaltrials.gov identifier:
NCT05417594

Treatment
Treatment study for people with advanced breast, ovarian, pancreatic or prostate cancer or gliomas

WISDOM Study: Women Informed to Screen Depending on Measures of Risk

Clinicaltrials.gov identifier:
NCT02620852

Prevention
Study to determine if breast cancer screening can be made better by personalizing each woman’s mammogram schedule

Observing People and Families Affected by Li-Fraumeni Syndrome (TP53 Mutation )

Clinicaltrials.gov identifier:
NCT01443468

Surveys, Registries, Interviews
Registry for people with Li-Fraumeni syndrome (LFS) or from LFS families

A Surveillance Program for Women at High Risk for Breast Cancer (CAPSBRACA)

Clinicaltrials.gov identifier:
NCT03729115

Surveys, Registries, Interviews
Screening study for women at risk for breast cancer due to an inherited mutation or other risk factor

Nipple Sparing Mastectomy With Immediate Implant-Based Reconstruction for Women With Early-Stage Breast Cancer

Clinicaltrials.gov identifier:
NCT05720039

Treatment
Nipple sparing mastectomy with reconstruction for women with early-stage breast cancer

TAPUR Study: Testing FDA Approved Drugs Targeting Tumor Biomarkers in People with Advanced Stage Cancer

Clinicaltrials.gov identifier:
NCT02693535

Treatment
Cancer treatment study for people with advanced solid tumors

Self -Perception and Intimacy After the Cancer Experience (SPICE)

Surveys, Registries, Interviews
Online survey for cancer survivors ages 18-39 years old about sexual health

Opening the Conversation

Clinicaltrials.gov identifier:
NCT04806724

Quality of Life
Online communication program for breast and gynecologic cancer survivors and their partners

Treating Metastatic Solid Tumors with an Inherited or Acquired Gene Mutation Using the PARP Inhibitor Talazoparib

Clinicaltrials.gov identifier:
NCT04550494

Treatment
Treatment study for people with advanced solid tumors

Restoring Sensation after DIEP Flap Reconstruction

Clinicaltrials.gov identifier:
NCT04533373

Prevention
Study for people undergoing DIEP flap reconstruction

Tools To Be Fit: Tools to Improve Nutrition and Physical Activity for Cancer Survivors

Clinicaltrials.gov identifier:
NCT05056077

Quality of Life
Bladder, breast, colon, endometrial, kidney (renal cell carcinoma), ovarian, prostate, or rectal cancer

Factors Influencing Disparities in Quality of Life among People of Color Affected by Cancer

Surveys, Registries, Interviews
Survey for people of color who have completed treatment for cancer

NUV-868 Alone and in Combination With PARP Inhibitors in Patients With Advanced Solid Tumors

Clinicaltrials.gov identifier:
NCT05252390

Treatment
Treatment study for people with advanced solid tumors, including triple-negative breast, ovarian, pancreatic and prostate cancer

Helping Latinas Understand Their Risk for Breast Cancer and Get Breast Cancer Care

Clinicaltrials.gov identifier:
NCT05483283

Prevention
Latinas with a high risk of breast cancer

Cancer Experience Registry

Surveys, Registries, Interviews
Online survey for patients and caregivers focusing on multiple aspects of cancer

SHARON: A Clinical Trial for Metastatic Cancer With an Inherited BRCA or PALB2 Mutation Using Chemotherapy and Patients’ Own Stem Cells

Clinicaltrials.gov identifier:
NCT04150042

Treatment
Advanced pancreatic cancer or stage 4 breast cancer in people with a BRCA1 or BRCA2 mutation

Treating Early-Stage Breast Cancer with a PARP Inhibitor (Niraparib) and Immunotherapy (Dostarlimab) in People with a BRCA or PALB2 Mutation

Clinicaltrials.gov identifier:
NCT04584255

Treatment
Treatment before surgery for people with early-stage breast cancer & a BRCA1, BRCA2 or PALB2 mutation

Investigational PARP Inhibitor AZD5305 Alone or Combined With Other Anti-cancer Agents in People With Advanced Solid Tumors (PETRA)

Clinicaltrials.gov identifier:
NCT04644068

Treatment
Advanced ovarian, breast, prostate or pancreatic cancer

Treatment with ATR Inhibitor for Advanced or Metastatic Solid Tumors

Clinicaltrials.gov identifier:
NCT04657068

Treatment
Advanced solid tumors

Blood Tests to Measure Ovarian Reserves in Women with a BRCA Mutation or Women Treated for Early-Stage Breast Cancer

Clinicaltrials.gov identifier:
NCT00823654

Prevention
Study for premenopausal women with early-stage breast cancer and high-risk women with BRCA mutations and no evidence of breast or ovarian cancer

Talazoparib for People with Metastatic Breast Cancer Who Have Acquired (Somatic) BRCA Mutations

Clinicaltrials.gov identifier:
NCT03990896

Treatment
This is a study for people with metastatic breast cancer without a known mutation in BRCA1 or BRCA2, who learn they have a BRCA1 or BRCA2 acquired tumor mutation (somatic mutation) found through liquid biopsy

A Randomized Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Metastatic Breast, Ovarian, Prostate and Pancreatic Cancer Patients (E-Reach)

Clinicaltrials.gov identifier:
NCT04353973

Treatment

Study for People with Unexpected Genetic Results

Clinicaltrials.gov identifier:
NCT02595957

Prevention
This study is recruiting people who received unexpected genetic test results about their cancer risk after having genetic testing done for some other reason

Talking to Employers and Medical Staff About Breast Cancer Treatment and Your Job

Clinicaltrials.gov identifier:
NCT03572374

Quality of Life
Study for people diagnosed with cancer to help them navigate wok-related issues

ELLIE's Project

Quality of Life
A survey to gain a better understanding of the baseline lifestyle factors related to nutrition and physical activity in people with a hereditary cancer gene mutation.