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Featured Studies Results

Comparing the Targeted Therapy Daraxonrasib With or Without Chemotherapy to Chemotherapy Alone for First-Line Treatment of Metastatic Pancreatic Cancer (RASolute 303)

https://www.facingourrisk.org/research-clinical-trials/study/407 /comparing-daraxonrasib-with-or-without-chemotherapy-to-chemotherapy-alone-for-first-line-treatment-of-metastatic-pancreatic-cancer

Clinicaltrials.gov identifier:
NCT07491445 (https://clinicaltrials.gov/show/NCT07491445)

Treatment
Phase 3 Study for First-Line Treatment of Metastatic Pancreatic Cancer

A Study to Learn About the Study Medicine Called PF-07248144 in Combination with Fulvestrant in People with HR-positive, HER2-negative Advanced or Metastatic Breast Cancer who Progressed After a Prior Line of Treatment

https://www.facingourrisk.org/research-clinical-trials/study/414 /a-study-to-learn-about-the-study-medicine-called-pf-07248144-in-combination-with-fulvestrant-in-people-with-hr-positive-her2-negative-advanced-or-metastatic-breast-cancer-who-progressed-after-a-prior-line-of-treatment

Clinicaltrials.gov identifier:
NCT07062965 (https://clinicaltrials.gov/show/NCT07062965)

Treatment
Phase 3 study for adults with advanced/metastatic HR-positive, HER2-negative breast cancer who have progressed from prior treatment

Testing COM701 Maintenance Treatment to Delay Cancer Growth After Platinum Chemotherapy for Ovarian Cancer That Has Come Back

https://www.facingourrisk.org/research-clinical-trials/study/381 /testing-com701-maintenance-treatment-to-delay-cancer-growth-after-platinum-chemotherapy-for-ovarian-cancer-that-has-come-back

Clinicaltrials.gov identifier:
NCT06888921 (https://clinicaltrials.gov/show/NCT06888921)

Treatment
Study for relapsed platinum-sensitive ovarian cancer

FIT Testing for Colorectal Cancer Screening in People with Lynch Syndrome

https://www.facingourrisk.org/research-clinical-trials/study/418 /fit-testing-for-colorectal-cancer-screening-in-people-with-lynch-syndrome

Clinicaltrials.gov identifier:
NCT06898996 (https://clinicaltrials.gov/show/NCT06898996)

Prevention
Colon cancer screening study for people with Lynch syndrome

Treating Advanced MSI-High or dMMR Cancers Using the Targeted Therapy MOMA-341 Given Alone or In Combination with Standard Therapies

https://www.facingourrisk.org/research-clinical-trials/study/356 /treating-advanced-msi-high-or-dmmr-cancers-using-the-targeted-therapy-moma-341-given-alone-or-in-combination-with-standard-therapies

Clinicaltrials.gov identifier:
NCT06974110 (https://clinicaltrials.gov/show/NCT06974110)

Treatment
Treatment study for people with advanced or metastatic cancers

Research Study on the Genetics of Breast Cancer

https://www.facingourrisk.org/research-clinical-trials/study/317 /research-study-on-the-genetics-of-breast-cancer

Clinicaltrials.gov identifier:
NCT06773897 (https://clinicaltrials.gov/show/NCT06773897)

Surveys, Registries, Interviews
A registry for anyone aged 18 and older who lives in the United States

Understanding Risk Factors for Stomach Cancer in People with Inherited Mutations

https://www.facingourrisk.org/research-clinical-trials/study/332 /understanding-risk-factors-for-stomach-cancer-in-people-with-inherited-mutations

Surveys, Registries, Interviews
Online survey on stomach cancer risk for people with an inherited mutation in genes that are linked to an increased risk of certain cancers

Multi-Cancer Detection Blood Tests in Adults Without Cancer: Vanguard Study

https://www.facingourrisk.org/research-clinical-trials/study/394 /multi-cancer-detection-blood-tests-in-adults-without-cancer-vanguard-study

Clinicaltrials.gov identifier:
NCT06995898 (https://clinicaltrials.gov/show/NCT06995898)

Prevention
A study testing two multi-cancer detection blood tests in people who do not have cancer

Please Help us Learn More About Immunotherapy Side Effects That People With Cancer Experience

https://www.facingourrisk.org/research-clinical-trials/study/421 /a-5-minute-patient-and-caregiver-survey-to-share-experiences-with-immunotherapy-and-any-short-term-or-long-term-side-effects

Surveys, Registries, Interviews
This 5-minute survey allows cancer patients on immunotherapy (currently or in the past) and their caregivers to share their experiences, including their side effects and whether they were resolved or not.

The FYI on MRI: A Decision Support Intervention for Screening Breast MRI for Black and Latina Women

https://www.facingourrisk.org/research-clinical-trials/study/406 /the-fyi-on-mri-a-decision-support-intervention-for-screening-breast-mri

Clinicaltrials.gov identifier:
NCT06892275 (https://clinicaltrials.gov/show/NCT06892275)

Surveys, Registries, Interviews
Feedback survey on materials about breast MRI

Comparing Shorter vs. Standard Radiation for High-Risk Prostate Cancer (High Five)

https://www.facingourrisk.org/research-clinical-trials/study/397 /comparing-shorter-vs-standard-radiation-for-high-risk-prostate-cancer

Clinicaltrials.gov identifier:
NCT05946213 (https://clinicaltrials.gov/show/NCT05946213)

Treatment
Phase 3 treatment study for high-risk prostate cancer

Using the Drug Daraxonrasib in Surgically Removed Pancreatic Cancer (RASolute 304)

https://www.facingourrisk.org/research-clinical-trials/study/389 /using-the-drug-daraxonrasib-in-surgically-removed-pancreatic-cancer-rasolute-304

Clinicaltrials.gov identifier:
NCT07252232 (https://clinicaltrials.gov/show/NCT07252232)

Treatment
Phase 3 study for pancreatic cancer treatment after surgery and chemotherapy

Evaluating the Safety of Nipple Sparing Mastectomy in Women With a High Risk for Breast Cancer

https://www.facingourrisk.org/research-clinical-trials/study/392 /evaluating-the-safety-of-nipple-sparing-mastectomy-in-women-with-a-high-risk-for-breast-cancer

Clinicaltrials.gov identifier:
NCT06888388 (https://clinicaltrials.gov/show/NCT06888388)

Prevention
Study for people considering double mastectomy to reduce breast cancer risk

Using a Mobile Health App to Improve Quality of Life in Black Men with Prostate Cancer

https://www.facingourrisk.org/research-clinical-trials/study/411 /using-a-mobile-health-app-to-improve-quality-of-life-in-black-men-with-prostate-cancer

Clinicaltrials.gov identifier:
NCT06651359 (https://clinicaltrials.gov/show/NCT06651359)

Quality of Life
Quality of life study for Black men with prostate cancer

Study of a New Oral Medication, Daraxonrasib After Surgery to Help Prevent Pancreatic Cancer from Returning

https://www.facingourrisk.org/research-clinical-trials/study/378 /study-of-a-new-oral-medication-daraxonrasib-after-surgery-to-help-prevent-pancreatic-cancer-from-returning

Clinicaltrials.gov identifier:
NCT07252232 (https://clinicaltrials.gov/show/NCT07252232)

Treatment
Phase 3 treatment trial for pancreatic cancer that was removed by surgery

ENGAGE: Surveys to Assess Decision-Making on Genetic Counseling and Testing for Lynch Syndrome

https://www.facingourrisk.org/research-clinical-trials/study/416 /engage-surveys-to-assess-decision-making-on-genetic-counseling-and-testing-for-lynch-syndrome

Clinicaltrials.gov identifier:
NCT07106359 (https://clinicaltrials.gov/show/NCT07106359)

Surveys, Registries, Interviews
Clinical trial for untested individuals at risk for Lynch syndrome

Share Your Child's Genetic Diagnostic Journey

https://www.facingourrisk.org/research-clinical-trials/study/417 /share-your-childs-genetic-diagnostic-journey

Surveys, Registries, Interviews
Interview with Latino/a parents about their child's genetic care

Experiences with Genetic Counseling Among Individuals with a BRCA1 or BRCA2 Genetic Mutation

https://www.facingourrisk.org/research-clinical-trials/study/415 /experiences-with-genetic-counseling-among-individuals-with-a-brca1-or-brca2-genetic-mutation

Surveys, Registries, Interviews
Survey for people with a positive BRCA1 and/or BRCA2 mutation.

About FORCE

FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.