Colorectal Cancer Treatment
Learn about national guidelines and colorectal cancer treatment options for people with inherited mutations.Stay up to date on research and information
Sign Up for FORCE NewslettersColorectal Cancer Treatment
Treatment for colorectal cancer depends on the stage and type of the disease based on pathology results. Tumor biomarker testing and genetic testing can provide additional clues about which treatments may work best against your cancer. Additional tests are usually recommended for people with metastatic or advanced cancer..
Standard treatment may include a combination of surgery, chemotherapy and radiation. Some people may also benefit from treatment with immunotherapies or targeted therapies. Clinical trials may be available for any stage of cancer.
About 17 percent of people diagnosed with colorectal cancer will test positive for an inherited mutation. People with an inherited mutation in the genes below may have different treatment recommendations or options depending on their gene mutation.
Make sure that you receive a copy of your cancer test results, including your pathology report and your stage. Ask your doctor to explain your diagnosis, test results and treatment options in terms that you can understand. This will allow you to work with your doctor to choose a treatment plan that is right for you.
See below for more information on each of these colorectal cancer treatment topics.
More Information on Colorectal Cancer Treatment Options
Stages & Subtypes
Treatment for colorectal cancer depends on the stage and type based on pathology results. Learn about how doctors determine the stage and subtype of colorectal cancers.
Standard Therapies
Treatment for colorectal cancer often includes a combination of surgery, chemotherapy and radiation. Learn more about these types of treatments.
Genetic & Biomarker Testing
Tumor biomarker testing and genetic testing can provide additional clues about which treatments may work best against your cancer.
Targeted & Immunotherapies
Targeted therapies are designed to attack or kill cancer cells, while sparing normal cells as much as possible. Immunotherapies are cancer treatments that help the body’s immune system detect and attack cancer cells.
Participate in Colorectal Cancer Treatment Research
Below are some of our featured research studies looking at new treatments for colorectal cancer treatment. To search for more studies, visit our Search and Enroll Tool.
Clinicaltrials.gov identifier:
NCT05572684
A Study of the Drug REC-4881 For Treating People with Advanced Cancers with an APC or AXIN1 Mutation
Clinicaltrials.gov identifier:
NCT06005974
Clinicaltrials.gov identifier:
NCT05217446
Clinicaltrials.gov identifier:
NCT03803553
Treatment of HER2-positive Colorectal Cancer as First Line Treatment in the Metastatic Setting
Clinicaltrials.gov identifier:
NCT05253651
