Read about different genes that are linked to hereditary cancer, their associated risks and guidelines for screening, preventing and treating cancers in people with inherited mutations in these genes.
General information for people with inherited mutations
Both men and women can carry a mutation in the gene.
People with an inherited mutation in have increased risk for certain cancers. See our Cancer Risk section for more information. There are guidelines for screening and prevention for certain cancers in people with a mutation. Clinical trials may also be available for people who test positive for a mutation. See our Risk Management section for more information about screening options in people with mutations.
People with a mutation who have been diagnosed with cancer may qualify for specific treatments or clinical trials. Visit our Cancer Treatment section for more information about treatment clinical trials for people with a mutation.
Inheriting two mutations in —one from each parent—causes a rare disease known as Fanconi anemia. See our Other Considerations section for more information about this disease.
mutations can be found in people of every race and ethnicity. However, people of Eastern European (Ashkenazi) Jewish ancestry are more likely to have an inherited mutation than people who are not of Jewish descent.
The name stands for "Breast Cancer 2." The gene is located on chromosome 13. helps to repair damaged .
FORCE offers many peer support programs for people with inherited mutations.
- Our Message Boards allow people to connect with others who share their situation. Once registered, you can post on the Diagnosed With Cancer board to connect with other people who have been diagnosed.
- Our Peer Navigation Program will match you with a volunteer who shares your mutation and situation.
- Our moderated, private Facebook group allows you to connect with other community members 24/7.
- Check out our virtual and in-person support meeting calendar.
- Join one of our Zoom community group meetings:
- Meetings in American Sign Language
- Meetings in Spanish
- People of Color
- Young Previvors
- Young Survivors